Journals / Geriatrik Bilimler Dergisi / 2021 / Cilt: 4 - Sayı: 2

Safety of Levofloxacin in Older Adults

Yaşlılarda Levofloksasin Kullanımının Güvenliliği

Pages
45–51
Publication Date
2021-08-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, we aimed to investigate the safety of levofloxacin, which provides many advantages in older patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Levofloxacin is one of the most prescribed antibacterial agents.
📊
Key Findings & Data:They are used for the treatment of many infections, which are of paramount importance for geriatric practice.
💡
Conclusion & Impact:In this study, we aimed to investigate the safety of levofloxacin, which provides many advantages in older patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Apati · Deliryum · Levofloksasin

Abstract

Aim: Levofloxacin is one of the most prescribed antibacterial agents. They are used for the treatment of many infections, which are of paramount importance for geriatric practice. In this study, we aimed to investigate the safety of levofloxacin, which provides many advantages in older patients.

Özet

Amaç: Levofloksasin en sık reçete edilen antibakteriyel ajanlardan biridir. Geriatri pratiğinde önemli olan birçok enfeksiyonun tedavisinde kullanılmaktadır. Bu çalışmada yaşlı hastalarda birçok avantaj sağlayan levofloksasinin güvenilirliğini araştırmayı amaçladık.

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Cite This Article

SAKAR, K., AYDIN, A. E., DOKUZLAR, Ö., KOCYIGIT, S. E. (2021). Safety of Levofloxacin in Older Adults. Geriatrik Bilimler Dergisi, Cilt: 4 - Sayı: 2, 45–51. https://ajindex.com/articles/761387

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References (17)

  1. Liu X, Ma J, Huang L, et al. Fluoroquinolones increase the risk of serious arrhythmias: A systematic review and meta-analysis. Medicine (Baltimore). 2017; 96(44):e8273
  2. Bidell MR, Lodise TP. Fluoroquinolone-Associated Tendinopathy: Does Levofloxacin Pose the Greatest Risk? Pharmacotherapy. 2016; 36(6):679–93
  3. Yoshikawa TT, Livesley NJ, Chow AW. Infected Pressure Ulcers in Elderly Individuals. Clin Infect Dis. 2002; 35(11):1390–6
  4. Ates Bulut E, Soysal P, Isik AT. Frequency and coincidence of geriatric syndromes according to age groups: Single-center experience in Turkey between 2013 and 2017. Clin Interv Aging. 2018;13:1899–905
  5. Gao CH, Yu LS, Zeng S, et al. Personalized therapeutics for levofloxacin: A focus on pharmacokinetic concerns. Ther Clin Risk Manag. 2014; 10:217–27
  6. Noreddin AM, Elkhatib WF. Levofloxacin in the treatment of community-acquired pneumonia. Expert Rev Anti Infect Ther. 2010; 8(5):505–14
  7. Kuula LSM, Viljemaa KM, Backman JT, et al. Fluoroquinolone-related adverse events resulting in health service use and costs: A systematic review. PLoS One. 2019; 14(4):e0216029
  8. Liu HH. Safety profile of the fluoroquinolones: Focus on levofloxacin. Drug Saf. 2010; 33(5):353–69
  9. Shi S, Klotz U. Age-related changes in pharmacokinetics. Curr Drug Metab. 2011; 12(7):601–10
  10. Hooper,DC. Fluoroquinolones. https://www.uptodate.com/contents/fluoroquinolones?search=levofloxacin%20drug%20information&source=search_result&selectedTitle=1~145&usage_type=default&display_rank=1#H2783446913. Accessed June 3, 2019
  11. Bazett HC. An analysis of the time-relations of electrocardiograms. Heart. 1920; 7:353–70
  12. Straus SMJM, Kors JA, De Bruin ML, et al. Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol. 2006; 47(2):362–7
  13. Vandael E, Vandenberk B, Vandenberghe J, et al. Risk factors for QTc-prolongation: systematic review of the evidence. Int J Clin Pharm. 2017; 39(1):16–25
  14. Marin RS, Biedrzycki RC, Firinciogullari S. Reliability and validity of the apathy evaluation scale. Psychiatry Res. 1991; 38(2):143–62
  15. Gulseren S, Atun C, Erol A, et al. Apati değerlendirme ölçeği Türkçe formunun geçerlilik ve güvenilirlik çalışması. Nöropsikiatri Arşivi. 2001; 38(3):142–50
  16. Inouye SK, Van Dyck CH, Alessi CA, et al. Clarifying confusion: The confusion assessment method: A new method for detection of delirium. Ann Intern Med. 1990; 113(12):941–8
  17. Tsai WC, Yang YM. Fluoroquino