Sacroiliitis in patients with multiple sclerosis

Key Findings & Data:Study design: Retrospective study Materials & methods: Forty-three patients (15 male and 28 female) with multiple sclerosis included in this study.

💡

Conclusion & Impact:Conclusion:! he results of these study showed that sacroiliilis could be seen in multiple sclerosis patients.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Objective: A possible association between ankylosing spondylilis and multiple sclerosis has been suggested. The aim of this study was to evaluate the sacroiliitis in multiple sclerosis patients. Study design: Retrospective study Materials & methods: Forty-three patients (15 male and 28 female) with multiple sclerosis included in this study. Results: The mean age was 38.9 ± 10.1 years. The mean duration of disease was 7.5 ±6.2 years. All the patients who were followed up by multiple sclerosis diagnosis were evaluated by magnetic resonance imaging. Eight (18.6 %) of multiple sclerosis patients had bilateral sacroiliitis. One of the patients was female and she had ankylosing spondylilis. Sacroiliitis was determined in three patients with plain radiography. Sacroiliilis was diagnosed in 5 (17.9 %) of the female patients (20%) and 3 of male patients (p= 0.1). There were no statistically significant difference between the ages of multiple sclerosis onset, durations of the disease ami the Hxpanded Disability Status Scale scores of patients with sacroiliitis and patients whose sacroiliac joint findings were normal. Conclusion:! he results of these study showed that sacroiliilis could be seen in multiple sclerosis patients.

Özet

Amaç: Ankilozan spondilit ile multipl skleroz anısında olası bir bağlantı olduğu düşünülmüştür. Bu çalışmanın amacı multipl skleroz hastalarında sakroileiti değerlendirmektir. Çalışma düzeni: Retrospeklif çalışma Gereç ve yöntem: Multipl sklerozu olan 43 hasta (15 erkek ve 28 kadın) bu çalışmaya dahil edilmiştir. Bulgular: Ortalama yaş 38.91±10.1 yıldır. Ortalama hastalık süresi 7.5±6.2 yıldır. Multipl skleroz tanısıyla takip edilen bütün hastalar manyetik rezonans görüntülenmesiyle değerlendirilmiştir. Sekiz (% 18.6) mullipl skleroz hastasında bilateral sakroileit vardır. Muştalardan biri kadın ve bu hastanın ankilozan spondiliti mevcut idi. Sakroiliitis üç hastada düz radyografiyle belirlenmiştir. Kadın hastaların 5'inde (%17.9) ve erkek hastaların 3'ünde (%20) sakroileit tanısı konulmuştur (p=0.1). Sakroilciti olan hastalar ve sakroiliyak eklem bulguları normal olan hastalar arasında multipl sklerozun başlama yaşı. hastalık süresi ve Genişletilmiş İşgöremczlik Durumu Ölçeği skorları yönünden istatistiksel olarak anlamlı bir fark yoktur. Sonuç: Bu çalışmanın sonuçları sakroileitin multipl sklerozlu hastalarda görülebileceğini göstermiştir.

🔖

Cite This Article

ÇİDEM, M., SARIYILDIZ, M. A., GÜNAYDIN, Ş., KARACAN, İ., AYDIN, T. (2022). Sacroiliitis in patients with multiple sclerosis. Bezm-i Alem Valide Sultan SSK Vakıf Gureba Eğitim Hastanesi Derg., Cilt: 3 - Sayı: 1, 31–33. https://ajindex.com/articles/464181

References (9)

Zhang Z., Duvefelt K., Svensson R, et al. Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis. Genes Immun. 2005; 27 [Epub ahead of print] Ragonese P., Salemi G., D'Amelio M., Gammino M., Aridon P., Savettieri G. Multiple sclerosis in southern Europe: Monreale City, Italy. A twenty-year follow-up incidence and prevalence study. Neuroepidemiology. 2004;23:306-9.
Gran JT., Husby G. Epidemiology of ankylosing spondylitis. In Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman WH editors Rheumatology third edition Edinburg Mosby 2003:1153-60
A.Whitman GJ., Khan MA. Unusual occurrence of ankylosing spondylitis and MS in a black patient. Cleve Clin J Med. 1989;56:819-22.
Hanrahan PS., Russell AS., McLean DR. Ankylosing spondylitis and MS: an apparent association? J Rheumatol. 1988;15:1512-4. Calin A. Is there an association between ankylosing spondylitis and MS? Ann Rheum Dis. 1989;48:971-2. 7.Khan MA., Kushner I. Ankylosing spondylitis and MS: a possible association. Arthritis Rheum. 1979;22:784-6.
Cellerini M., Gabbrielli S., Bongi SM. Cerebral magnetic resonance imaging in a patient with ankylosing spondylitis and MS-like syndrome. Neuroradiology. 2001;43:1067-9.
Pillay N., Hunter T. Delayed evoked potentials in patients with ankylosing spondylitis. J Rheumatol. 1986;13:137-41. lO.Libbrecht N., De Bleecker J. Ankylosing spondylitis and MS. Acta Clin Belg. 1999;54:30-2.
Dolan AL., Gibson T. Intrinsic spinal cord lesions in 2 patients with ankylosing spondylitis. J Rheumatol. 1994;21:1160-1. Khan MA. Clinical features of ankylosing spondylitis In Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman WH eds Rheumatology third edition Edinburg Mosby 2003:1173-4
Inane N., Atagunduz P., Sen R, et al. The investigation of sacroiliitis with different imaging techniques in spondy-loarthropathies. Rheumatol Int. 2004; 12 [Epub ahead of print] Puhakka KB., Jurik AG., Schiottz-Christensen B., et al. Magnetic resonance imaging of sacroiliitis in early seronegative spondylarthropathy. Abnormalities correlated to clinical and laboratory findings. Rheumatology (Oxford). 2004;43:234-7. Kurtzke J. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983; 33: 1444-52.
Resnick D., Niwayama G. Ankylosing Spondylitis. Differential Diagnosis In Resnick D, Niwayama G eds Diagnosis of Bone and Joint Disorders second edition Philadelphia WB Saunders co 1988:1161-2