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Dergiler / Journal of Experimental and Clinical Medicine / 2025 / Volume: 42 Issue: 4

EBV infection as a rare cause of acute cholestatic hepatitis: A case report

Furkan Çakmak(ONDOKUZ MAYIS ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-0990-7640
Handan Doğan Çakmak(ONDOKUZ MAYIS UNIVERSITY, INTERNAL MEDICINE (DR))0009-0000-9254-3835
Sayfa
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Yayın Tarihi
2025-12-31
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Timely recognition may prevent unnecessary invasive procedures and ensure appropriate management.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Epstein-Barr virus (EBV) is a common herpesvirus, often presenting as infectious mononucleosis.
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Temel Bulgular & Veri:While mild hepatic enzyme elevations are common in EBV infection, cholestatic hepatitis with significant hyperbilirubinemia is rare, occurring in less than 5% of cases.
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Sonuç & Katkı:Timely recognition may prevent unnecessary invasive procedures and ensure appropriate management.
🔬Tür:Case Report
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:ebstein-barr virus · cholestatic hepatitis · infectious mononucleosis

Abstract

Epstein-Barr virus (EBV) is a common herpesvirus, often presenting as infectious mononucleosis. While mild hepatic enzyme elevations are common in EBV infection, cholestatic hepatitis with significant hyperbilirubinemia is rare, occurring in less than 5% of cases. A 21-year-old female presented with epigastric pain and elevated liver enzymes with cholestatic pattern. Imaging excluded biliary obstruction. Serologic testing confirmed acute EBV infection. Other viral and autoimmune causes were ruled out. The patient improved with supportive care and was discharged. Although uncommon, EBV should be considered in the differential diagnosis of cholestatic hepatitis, particularly in young adults. Timely recognition may prevent unnecessary invasive procedures and ensure appropriate management.

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Bu Makaleye Atıf Yap

Çakmak, F., Çakmak, H. D. (2025). EBV infection as a rare cause of acute cholestatic hepatitis: A case report. Journal of Experimental and Clinical Medicine, Volume: 42 Issue: 4. https://ajindex.com/articles/1422560

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Kaynakça (8)

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