Journals / Türk Oftalmoloji Dergisi / 2003 / Cilt: 33 - Sayı: 1-1

Risk factors effecting visual acuity in non-insulin-dependent diabetic subjects with diabetic retinopathy

İnsüline bağımlı olmayan diyabetik retinopatili hastalarda görme keskinliği üzerine etkili risk faktörleri

Pages
134–141
Publication Date
2022-11-05
DOI
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Conclusion: In diabetic patients with diabetic retinopathy, it is important to know the risk factors effecting the visual acuity in determining the subjects who are under the risk for severe visual loss.

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Objective & Hypothesis:Purpose: To determine the risk factors effecting visual acuity in non-insulin-dependent diabetic subjects with diabetic'retinopathy.
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Key Findings & Data:Methods: 1504 eyes of 752 non-insulin-dependent diabetic patients attending to our clinic due to diabetic retinopathy were retrospectively analyzed.
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Conclusion & Impact:Conclusion: In diabetic patients with diabetic retinopathy, it is important to know the risk factors effecting the visual acuity in determining the subjects who are under the risk for severe visual loss.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To determine the risk factors effecting visual acuity in non-insulin-dependent diabetic subjects with diabetic'retinopathy. Methods: 1504 eyes of 752 non-insulin-dependent diabetic patients attending to our clinic due to diabetic retinopathy were retrospectively analyzed. Medical story and detailed ocular findings were collected from patients' cards and records in diabetes clinic. Age, gender, age at the onset of diabetes, duration of diabetes, type of diabetes treatment, hemodialysis, hemoglobin Ale (HbAlc) level, and presence of hypertension (HT), age related macular degeneration (ARMD), glaucoma, cataract, neovascularisation of iris (NVI), clinically significant macular edema (CSME), cystoid macular edema (CME), intraocular hemorrhage (IOH), traction retinal detachment (TRD), preretinal hemorrhage, diabetic retinopathy (DR), branch retinal vein occlu-sion (BRVO) and neovascular glaucoma (NVG) were the factors, which were evaluated for the-ir effects on visual acuity. The multivariate-adjusted association between these factors and severe visual loss was evaluated with logistic regression analysis. On the other hand, Chi-square and Anova tests were used to investigate the independent effects of these factors on visual acuity. Results: As analyzed by multiple logistic regression model, HbAlc level, and presence of CME, NVG, IOH, TRD, ARMD, CSME, cataract, BRVO, preretinal hemorrhage and DR were found to be the statistically significant factors for severe visual loss (p0,05). On the other hand, when the factors were investigated independently, high HbAlc level, advanced age, and presence of cataract, NVI, NVG, CSME, CME, IOH, TRD, preretinal hemorrhage and proliferative DR were the statistically significant factors for visual loss (p0,05). Conclusion: In diabetic patients with diabetic retinopathy, it is important to know the risk factors effecting the visual acuity in determining the subjects who are under the risk for severe visual loss.

Özet

Amaç: İnsüline bağımlı olmayan diyabetik retinopatili hastalarda, görme keskinliği üzerinde etkili olan risk faktörlerini belirlemek Yöntem: Diyabetik retinopati nedeniyle kliniğimize başvuran 752 İnsüline bağımlı olmayan diyabetik hastanın 1504 gözü retrospektif olarak incelendi. Hastaların dosyalarından ve diyabet polikliniğindeki kayıtlarından, tıbbi hikayeleri ve ayrıntılı oküler muayene bulguları elde edildi. Görme keskinliği üzerine etkileri araştırılan faktörler yaş, cins, diyabetin başlangıç yaşı, diyabet süresi, diyabetin tedavi şekli, hemodiyaliz, hipertansiyon (HT), glikolize hemoglobin (HbAlc) seviyesi, yaşa bağlı maküla dejenerasyonu (YBMD), glokom, katarakt, iris neovaskülarizasyonu (İN), klinik anlamlı maküla ödemi (KAMÖ), kistoid maküla ödemi (KMÖ), intraoküler hemoraji (İOH), traksiyonel retina dekolmam (TRD), preretinal hemoraji, diyabetik reti-nopati (DR), retina ven dal tıkanıklığı (RVDT) ve neovasküler glokom (NVG) idi. Ciddi görme kaybı ve bu faktörler arasındaki çok değişkenli ilişki lojistik regresyon analizi ile değerlendirildi. Öte yandan, faktörlerin birbirinden bağımsız olarak görme keskinliği üzerine etkilerinin in-celenmesinde Ki-kare ve Anova testleri kullanıldı. Bulgular: Lojistik regresyon analizinde, istatistiksel olarak anlamlı ciddi görme kaybına yol açan faktörlerin HgAlc seviyesi, KMÖ, NVG, İOH, TRD, YBMD, KAMÖ, katarakt, RVDT, preretinal hemoraji ve DR olduğu bulunurken (p0,05). Faktörler birbirinden bağımsız incelendiğinde ise, yüksek HgAlc seviyesi, ileri yaş, katarakt, İN, NVG, KAMÖ, KMÖ, İOH, TRD, preretinal hemoraji ve proliferatif DR'li olgularda görme keskinliğinin istatistiksel olarak anlamlı düzeyde düşük olduğu görülürken (p0,05). Tartışma: Diyabetik retinopatili hastalarda görme keskinliği üzerine etkili olan risk faktörlerinin bilinmesi, ciddi görme kaybı açısından risk altında olan hastaların belirlenmesinde önemlidir.

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Cite This Article

YANYALI, A., ÖZMEN, D., KARAAĞAÇ, H., BAYRAK, Y., Nohutçu, A. F. (2022). Risk factors effecting visual acuity in non-insulin-dependent diabetic subjects with diabetic retinopathy. Türk Oftalmoloji Dergisi, Cilt: 33 - Sayı: 1-1, 134–141. https://ajindex.com/articles/638943

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