Journals / Türk Anestezi ve Reanimasyon Dergisi / 2008 / Cilt: 36 - Sayı: 3

Surveillance for vancomycin resistant enterococci colonization among high risk hospitalized patients

Hastanede yatan riskli hasta gruplarında vankomisine dirençli enterokok kolonizasyonunun sürveyansı

Pages
168–173
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

For this reason we suggest that the screening tests should be done periodically to reveal resistant strains earlier.

📌 3 Key Takeaways

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Objective & Hypothesis:Enterococci have been recognized as clinically important pathogens in high risk populations of hospitalized patients.
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Key Findings & Data:Rectal swabs were obtained from patients between 23 May 2003 and 27 August 2004 in Ankara University Hospitals.
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Conclusion & Impact:For this reason we suggest that the screening tests should be done periodically to reveal resistant strains earlier.
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Domain Parameters

Abstract

Enterococci have been recognized as clinically important pathogens in high risk populations of hospitalized patients. The role of enteroccocci in nosocomial infections is being recognized with increasing frequency. The main source of these infections is usually fecal carriage of the microorganisms. In this study, we investigated gastrointestinal colonization with vancomycin resistant enterococci (VRE) among high risk hospitalized patients prospectively. Rectal swabs were obtained from patients between 23 May 2003 and 27 August 2004 in Ankara University Hospitals. Nine of 467 patients (1.9 %) were found to be colonized with VRE. All strains were identified as Enterococcus faecium with high level resistance to vancomycin and teicoplanin. All nine strains defined as VRE had Van A gene which was detected by polymerase chain reaction (PCR) analysis. All the patients were hospitalized in intensive care units and were using wide spectrum antibiotics. Infection control precautions and prudent use of antibiotics are essential in limiting the emergence and spread of nosocomial VRE infections. The patients’ gastrointestinal tract is a possible reservoir for VRE and early detection is important for preventing its spread among hospitalized patients. For this reason we suggest that the screening tests should be done periodically to reveal resistant strains earlier.

Özet

Enterokoklar, hastanede yatan riskli hasta gruplarında klinik açıdan oldukça önemli patojendir. Nozokomiyal enfeksiyonlar arasındaki yeri ve önemi giderek artmıştır. Enterokokal enfeksiyonlarda temel kaynak mikroorganizmanın fekal taşıyıcılığıdır. Bu çalışma; 23 Mayıs 2003 ile 27 Ağustos 2004 tarihleri arasında; Ankara Üniversitesi hastanelerinde yatan riskli hasta gruplarının rektal sürüntü örneklerinde, vankomisine dirençli enterokok (VRE) kolonizasyonunu araştırmak amacıyla prospektif olarak yapıldı. Taranan 467 hastanın 9 (% 1.9)’unda VRE kolonizasyonu tespit edildi. Tüm suşlar vankomisin ve teikoplanine karşı yüksek dirençli Enterococcus faecium olarak belirlendi. Yapılan polimeraz zincir reaksiyonu (PCR) analizi ile de tüm suşlarda Van A direnç geni saptandı. VRE kolonizasyonu tespit edilen hastaların tümünde uzun süreli yoğun bakımda yatış öyküsü ve yoğun antibiyotik kullanımı mevcuttu. Enfeksiyon kontrol önlemleri ve akılcı antibiyotik kullanımı nozokomiyal VRE enfeksiyonlarının önlenmesinde esastır. Gastrointestinal sistem VRE’lar için önemli bir rezervuardır ve hospitalize hastalar arasında yayılımının önlenmesinde VRE’ların erken tespiti önemlidir. Bu nedenle düzenli aralıklarla hastane genelinde kolonizasyon taramalarının yapılmasını öneriyoruz.

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Cite This Article

AZAP, A., TEKELİ, A., AYGÜN, H., MEMİKOĞLU, O. K., YÖRÜK, F. (2022). Surveillance for vancomycin resistant enterococci colonization among high risk hospitalized patients. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 36 - Sayı: 3, 168–173. https://ajindex.com/articles/619965

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