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Journals / Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi / 2020 / Cilt: 34 - Sayı: 2

The Effect of Propolis on Oxidative Damage Induced by Whole Body Irradiation in Rat

Tüm Vücut Radyasyonu Uygulanan Ratlarda Oksidatif Hasar Üzerine Propolisin Etkisi

Mine ERİŞİR
Mehtap ÖZÇELİK
Osman GÜLER
Murat BAYKARA
Pages
75–80
Publication Date
2022-10-18
DOI
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⚡ TL;DR(Too Long; Didn't Read)

As a result of irradiation, a significant increase was determined inmalondialdehyde (MDA) levels of liver, kidney, and brain tissues of the rats (P

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Objective & Hypothesis:The antioxidant and radioprotective effects of propolis against ionizing radiation induced oxidativedamage were investigated.
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Key Findings & Data:Twenty one rats were divided in to 3 groups; 1 st group was the controlgroup; 2nd group was the irradiation group, physiological saline (i.p.)/ 3 days + 9 Gy gammairradiation; 3rd group was irradiation + Propolis group, propolis (i.p. 100 mg / kg BW) / 3 days + 9Gy gamma irradiation.
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Conclusion & Impact:As a result of irradiation, a significant increase was determined inmalondialdehyde (MDA) levels of liver, kidney, and brain tissues of the rats (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The antioxidant and radioprotective effects of propolis against ionizing radiation induced oxidativedamage were investigated. Twenty one rats were divided in to 3 groups; 1 st group was the controlgroup; 2nd group was the irradiation group, physiological saline (i.p.)/ 3 days + 9 Gy gammairradiation; 3rd group was irradiation + Propolis group, propolis (i.p. 100 mg / kg BW) / 3 days + 9Gy gamma irradiation. As a result of irradiation, a significant increase was determined inmalondialdehyde (MDA) levels of liver, kidney, and brain tissues of the rats (P

Özet

Radyasyona bağlı oksidatif hasara karşı propolisin antioksidan ve radyoprotektif etkileri araştırıldı. Yirmi bir rat 3 gruba bölündü; 1. grup kontrol grubu; 2. grup radyasyon grubu; serum fizyolojik (i.p.)/3 gün + 9 Gy gamma radyasyon; 3. grup radyasyon + propolis grubu; propolis (i.p. 100 mg/kg CA)/3 gün + 9 Gy gamma radyasyon uygulandı. Radyasyon sonucu, ratların karaciğer, böbrek ve beyin dokularının malondialdehit (MDA) düzeylerinde anlamlı bir artış tespit edildi (P

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Cite This Article

ERİŞİR, M., ÖZÇELİK, M., GÜLER, O., BAYKARA, M. (2022). The Effect of Propolis on Oxidative Damage Induced by Whole Body Irradiation in Rat. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi, Cilt: 34 - Sayı: 2, 75–80. https://ajindex.com/articles/507722

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