SavedAdd your journal

Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2006 / Cilt: 12 - Sayı: 1

Deneysel olarak doku dejenerasyonu oluşturulmuş kazlarda karaciğer ve böbrek arginaz aktivitesi değişimleri

Changes in liver and kidney arginase activities of geese after experimental tissue damage

AYSEL GÜVEN
İNAN KAYA
HACİ AHMET DEVECİ
MİNE ERİŞİR
NADİDE NABİL KAMİLOĞLU
Alpaslan Kadir DEVRİM
Pages
53–56
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These results show that arginase activity in the liver and kidney of geese is affected by cell damage.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The changes in arginase activity in the liver and kidney of geese were investigated through long-term treatment with carbon tetrachloride (CCU) and ethanol (C2H5OH).
📊
Key Findings & Data:Compared to the control group, arginase activity in the kidneys and liver of the CCU treatment groups was found to be significantly decreased.
💡
Conclusion & Impact:These results show that arginase activity in the liver and kidney of geese is affected by cell damage.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:böbrekler · kümes hayvanları · zehirlenme

Abstract

The changes in arginase activity in the liver and kidney of geese were investigated through long-term treatment with carbon tetrachloride (CCU) and ethanol (C2H5OH). Compared to the control group, arginase activity in the kidneys and liver of the CCU treatment groups was found to be significantly decreased. Arginase activity in the kidney of the ethanol treated group was found to be significantly increased, whereas no significant differences were found in the hepatic arginase activity. These results show that arginase activity in the liver and kidney of geese is affected by cell damage. The kidney arginase is more sensitive than the liver arginase to cell damage.

Özet

Uzun süre karbon tetraklorür (CCk) ve etanol (C2H5OH) verilen kazlarda karaciğer ve böbrek arginaz aktiviteleri incelendi. CCU verilen gruptaki böbrek ve karaciğer arginaz aktiviteleri kontrol grubu ile karşılaş­tırıldığında önemli derecede düşük bulundu. Etanol verilen grupta ise böbrek arginaz aktivitesi önemli derecede yüksek bulunurken karaciğerde önemli derecede değişiklik gözlenmemiştir. Sonuçta, karaciğer ve böbrek hücrelerinin zarar gördüğü, arginaz aktivitesİnde de değişim olduğu ve bu değişimde böbreklerin karaciğere göre daha fazla etkilendiği görülmüştür.

🔖

Cite This Article

GÜVEN, A., KAYA, İ., DEVECİ, H. A., ERİŞİR, M., KAMİLOĞLU, N. N., DEVRİM, A. K. (2006). Deneysel olarak doku dejenerasyonu oluşturulmuş kazlarda karaciğer ve böbrek arginaz aktivitesi değişimleri. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 12 - Sayı: 1, 53–56. https://ajindex.com/articles/273917

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Weber LW, Boll M, Stampfl A: Hepatotoxicity and mechanism öf action of haloalkans: Carbon 1tetrachloride as a toxicological model. Crit Rev Toxicol, 33, 105-136,2003.
  2. Güven A, Güven A, Gülmez M: The effect of kefir on the activities of 'GSH-Px, GST, CAT, GSH and LPO levels in carbon tetrachloride-Induced Mice Tissues. J Ve. Med B, 50, 412-416,2003. ' ' Güven A, Maraşlı N, Kaya N: Changes in the lipid peroxide status of geese in chronic carbon tetrachloride poisoning, Indian Vet J, 80,508-510,2003.
  3. Güven A, Kaya N: Determination of reduced glutathione, glutathione -S-transferase and selenium levels in goose liver cells with damage induced by carbon tetrachloride and ethanol. Turk J Vet Anim Scı, 29, 1233-1238, 2005.
  4. Beytut E, Güven A, Kamiloğlu NN: Alterations in erthrocyte antioxidant System after chronic administration of high dose of ethanol to mice. Kafkas Üniv Vet Fak Derg, 9(2): 137-140, 2003.
  5. Kadowaki H, Israel HW, Nesheim MC: Intracellular localization of arginase in chick kidney Biochimica et Biophysica Acta (BBA).-General Subjects, 437(1): 158-165, 1976. Kadowaki H^ Nesheim MC: Purification and properties of chick kidney arginase. International Journal of Biochemistry, 10(4): 303-310, 1979.
  6. Vecchio DA, Kalman SM: Ornithine transaminase in the liver of the chick embryo and in the young chick Archives of Biochemistry and Biophysics, 127,376-383, 1968.
  7. Gürsu MF, Doğrol M, Temizer Ozan S: Çeşitli türlerde plazma üre düzeyleri ile eritrosit arginazlan arasındaki ilişki. Fırat Üniv Sağlık Bilimleri Dergisi, 11(1): 91-98, 1997.
  8. Tamir S, Ratner S: Enzymes in arginine metabolism in chick. Arch. Biochem and Biophys, 102-209, 1963.
  9. Thurman RG, Bradford BU, Iimuro Y, Frankenberg MV, Knecht KI, Connor HD, Adachi Y, Wall C, Arteel GE, Raieigh JA, Forman DT, Mason RP: Mechanism of alchol- induced hepatotoxicity: studies in rats. Forntiers in Bioscience 4,42-46, 1999.
  10. Brzoska MM, Kami_ski M, Supernak-Bobko D, Zwierz K, Moniuszko-Jakoniuk J: Changes in the structure and function of the kidney of rats chronically exposed to cadmium. I. Biochemical and histopathological studies. Archives of Toxicology, 77, 344-352, 2003.
  11. Güven A, Kaya N: Determination of Reducte Glutathione (GSH), Glutathione S-Transferase (GST) and Selenium (Se) Levels in Goose Liver Cells with Damage Induced by Carbon Tetrachloride and Ethanol. Turkish Journal of Veterinary and Animal Science, 29, 1233-1238, 2005.
  12. Erişir M, Beytıt E, Ozan S, Aksakal M: Effects of dietary vitamine E and selenium on