Journals / Bezm-i Alem Valide Sultan SSK Vakıf Gureba Eğitim Hastanesi Derg. / 2005 / Cilt: 3 - Sayı: 3

Frequency and etiological factors of thrombocytosis inpatient population at the Bezm-i Alem Valide Sultan Vakif Gureba Training Hospital Internal Medicine Clinic

Bezm-i Alem Valide Sultan Vakıf Gureba Eğitim Hastanesi İç Hastalıkları Kliniğinde yatan hastalarda trombositoz sıklığı ve etyolojik faktörler

Pages
138–143
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

All hospitalized patients should be searched for thrombocytosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The goal of this study was to search the fre- quency and etiological factors of thrombocytosis in our inpatient population.
📊
Key Findings & Data:Materials & Medhods: The inpatient population of Bezm-i Alem Valide Sultan Vakif Gureba Training Hospital's (VGH) Internal Medicine Clinic was searched over a-4 years period for thrombocytosis.
💡
Conclusion & Impact:All hospitalized patients should be searched for thrombocytosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The goal of this study was to search the fre- quency and etiological factors of thrombocytosis in our inpatient population. Study design: Cross sectional study. Materials & Medhods: The inpatient population of Bezm-i Alem Valide Sultan Vakif Gureba Training Hospital's (VGH) Internal Medicine Clinic was searched over a-4 years period for thrombocytosis. Results: Throughout the evaluation period, 2.065 patients were hospitalized and 151 of them had an elevated platelet count. Eighty-three of 957 females (8.7%) and 67 of 1108 (6%) males had an elevated platelet count. Platelet counts in 63.3% (95 patients) of the cases were between 401.000 and 500.000/mm³ in 30.7% (46 patients) of the cases, counts were between 501.000 and 750.000/mm³; and in 6% (9 patients) of the cases, counts were more than 750.000/mm³. Infections were the most common causative disease group for thrombocytosis. Other common disease groups in order of frequency were anemias, collagen diseases, surgical cases, malign neoplasias and myeloproliferative disorders. Common individual causes of high platelet count in order of frequency were iron deficiency anemia, chronic obstructive pulmonary disease, pneumonia, tuberculosis, cancer, acute hemorrhage, and acute rheumatic fever. Thrombocytosis was more frequent among females, as were malign neoplasms as an etiological factor. There was no relationship between etiological factors and platelet levels. Possible etiology of high platelet count was not found for 39 patients (25.8%): 20 males and 19 females. For most of our cases, no platelet lowering treatment was required. Conclusion:Thrombocytosis is a relatively frequent finding in hospitalized patients. In certain conditions spesific therapies may require. All hospitalized patients should be searched for thrombocytosis.

Özet

Amaç: Bu çalışmanın amacı klinikte yatan hastalarımızda trombositoz sıklığı ve etyolojisinin araştırılması idi. Çalışma düzeni: Kesitsel çalışma Gereç ve Yöntem: Bezm-i Alem Valide Sultan Vakıf Gureba Eğitim Hastanesi İç Hastalıkları Kliniğinde 4 yıl boyunca yatırılarak tedavi edilen 2065 hastalar trombositoz varlığı ve etyolojisi açısından geriye dönük olarak araştırıldı. Bulgular: Değerlendirilen toplam 2065 hastadan 150'sinde (%7.3) trombosit sayısının normalden fazla olduğu tesbit edildi. Vakaların %63.3'ünü teşkil eden 95 hastada trombosit sayısı 401.000 - 500.000/mm³ arası, %30.7'sini teþkil eden 46 hastada 501.000 - 750.000/mm³ arası, %6'sını teşkil eden 9 vakada ise 750.000/mm³'den fazla idi. Dokuzyüzelliyedi kadın hastanın 83'ünde (%8.7), ve 1108 erkek hastanın 67'inde (%6) trombositoz vardı. Kadınlarda trombositoz erkeklere göre anlamlı derecede daha sık idi. Trombositozlara en fazla sebep olan hastalık grubu infeksiyonlar idi. Daha sonra, demir eksikliği anemisi, kollagen doku hastalıkları, cerrahi tablolar, habis neoplaziler ve miyeloproliferatif hastalıklar gelmekteydi. Kadınlarda habis neoplaziler erkeklerden anlamlı derecede daha sıktı. Diğer hastalık gruplarında ise iki cins arasında fark yoktu. Hastalıklar tek tek değerlendirildiğinde ise, demir eksikliği anemisi, kronik obstrüktif akciğer hastalığı alevlenmesi, pnömöni, tüberküloz, karsinomlar, akut hemoraji ve akut romatizmal ateş en sık rastlanan trombositoz sebepleri idi. Trombositozun etyolojisi ile ağırlık derecesi arasında bir ilişki yoktu. Vakalardan 9'u kadın 16'sı erkek olmak üzere 25'inde (%16.7) trombositozun muhtemel etyolojisi tesbit edilemedi. Hastaların çoğunda, trombositozu düzeltmeye yönelik bir tedavi uygulanmasına gerek duyulmamıştır. Sonuç: Yatan hastalarda trombositoza oldukça sık rastlanır. Bazı hallerde spesifik tedavi gerekebilir. Tüm yatan hastalar trombositoz yönünden araştırılmalıdır.

🔖

Cite This Article

UYANIKOĞLU, A., ERHAN, N., YILMAZ, D., CANBAZ, B., GÜNEY, M., DOĞAN, A. N., SARAÇOĞLU, A. S. (2022). Frequency and etiological factors of thrombocytosis inpatient population at the Bezm-i Alem Valide Sultan Vakif Gureba Training Hospital Internal Medicine Clinic. Bezm-i Alem Valide Sultan SSK Vakıf Gureba Eğitim Hastanesi Derg., Cilt: 3 - Sayı: 3, 138–143. https://ajindex.com/articles/464174

References (12)

  1. Williams WJ. Thrombocytosis. In: Williams WJ, Beutler E, Erslev AJ, Lichtman MA (Eds). Hematology. McGrawHill, 1991. p1403 -1406 2. Bouvenot G, Bartolin R, Heim M, et al. Thrombocytosis: general frequency and etiological circumstances (author's transl). Sem Hop. 1979 8-15
  2. 55(13-14):681 3. Buss DH, Cashell AW, O’Connor ML, et al. Occurrence, etiology, and clinical significance of extreme thrombocytosis: a study of 280 cases. Am J Med. 1994, 96: 247-53 4. Gurung AM, Carr B, Smith I. Thrombocytosis in intensive care. Br J Anaesth. 2001
  3. Randi ML, Fabris F, Girolami A. Thrombocytosis in young people: evaluation of 57 cases diagnosed before the age of 40. Blut. 1990, 60: 233-7 6. Santhosh-Kumar CR, Yohannan MD, Higgy KE, et al. Thrombocytosis in adults: analysis of 777 patients. J Intern Med. 1991
  4. 5 7. Sutor AH. Thrombocytosis in childhood. Semin Thromb Hemost. 1995
  5. 9 8. Vora AJ, Lilleyman JS. Secondary thrombocytosis. Arch Dis Child. 1993
  6. 90 9. Yohannan MD, Higgy KE, al Mashhadani SA, et al. Thrombocytosis. Etiologic analysis of 663 patients. Clin Pediatr (Phila). 1994
  7. 3 10. Fairbanks VF, Beutler E. Iron deficiency. Williams WJ, Beutler E, Erslev AJ, Lichtman MA (Eds). Hematology, McGraw-Hill. 1991
  8. 505 11. Dahlqvist SR, Nilsson TK, Norberg B. Thrombocytosis in active rheumatoid arthritis. Relation to other parameters of inflammatory activity and confounding effect of automated cell counting. Clin Rheumatol. 1988
  9. 41 12. Hutchinson RM, Davis P, Jayson MI. Thrombocytosis in rheumatoid arthritis. Ann Rheum Dis. 1976
  10. 42 13.Valade N, Decailliot F, Rebufat Y, et al. Thrombocytosis after trauma: incidence, aetiology, and clinical significance. Br J Anaesth. 2005
  11. 23 14. Bouvenot G, Escande M, Xeridat B, et al. Thrombocytosis and cancer. Apropos of a chronological series of 100 patients. Sem Hop. 1977, 53:1921-5 15. Aoe K, Hiraki A, Ueoka H, et al. Thrombocytosis as a useful prognostic indicator in patients with lung cancer. Respiration. 2004
  12. Pedersen LM, Milman N. The prognostic value of thrombocytosis in patients with primary lung cancer. Ugeskr Laeger. 1998, 160: 3917-20 17. Randi ML, Rossi C, Barbone E, et al. Incidence of thrombocytosis in lymphomas. Leuk Lymphoma. 1992, 7:139-41 18. Blatt J, Penchansky L, Horn M. Thrombocytosis as a presenting feature of acute lymphoblastic leukemia in childhood. Am J Hematol. 1989, 31: 46-9