Journals / Anadolu Kardiyoloji Dergisi / 2012 / Cilt: 12 - Sayı: 7

Hipertansiyonlu hastalarda aortik akımın ilerleme hızı ile bilek-brakiyal indeksin ilişkisi: Gözlemsel bir çalışma

Association of aortic flow propagation velocity with ankle-brachial blood pressure index in patients with hypertension: an observational study

Pages
568–573
Publication Date
2022-10-10
DOI
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Compared to control group E deceleration time of early diastolic flow velocity (184.0±32.2 vs. 217.1±38.6, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Endothelial dysfunction is considered the first stage in the development of atherosclerosis and assessed by flow-mediated dilatation (FMD) and aortic flow velocity propagation (AVP).
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Key Findings & Data:Methods: Sixty-eight patients with newly diagnosed hypertension and 34 healthy subjects were enrolled in the crosssectional observational study.
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Conclusion & Impact:Compared to control group E deceleration time of early diastolic flow velocity (184.0±32.2 vs. 217.1±38.6, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Endothelial dysfunction is considered the first stage in the development of atherosclerosis and assessed by flow-mediated dilatation (FMD) and aortic flow velocity propagation (AVP). Ankle-brachial index (ABI) is used to assess peripheral arterial disease and is associated with FMD but the relationship between ABI and AVP is unknown. In this study, we aimed to search the association between AVP, and ABI in patients with newly diagnosed hypertension. Methods: Sixty-eight patients with newly diagnosed hypertension and 34 healthy subjects were enrolled in the crosssectional observational study. The maximum ankle arterial pressures were divided by the maximum of the brachial arterial pressures to calculate the ABI. AVP was calculated from dividing the distance between points corresponding to the beginning and end of the propagation slope, to the duration between corresponding time points proximally descending aorta. Statistical analysis was performed using Student t-test, Chi-square test, Pearson correlation and linear regression analyses. Results: Age and gender of both groups were similar. Compared to control group E deceleration time of early diastolic flow velocity (184.0±32.2 vs. 217.1±38.6, p

Özet

Amaç: Endotel disfonksiyonu ateroskleroz gelişiminin ilk basamağı olarak kabul edilir ve akım aracılı dilatasyon (FMD) ve aortik yayılım hızı (AVP) ile değerlendirilebilir. Ankle-brakiyal indeks (ABİ) periferik arter hastalığı varlığını değerlendirmek için kullanılır. ABİnin FMD ile ilişkili olduğu bilinmektedir, ancak AVP ile ilişkisi bilinmemektedir. Bu çalışmada, yeni tanı konmuş hipertansif hastalarda AVP ile ABİ arasındaki ilişkiyi araştırmayı hedefledik. Yöntemler: Yeni tanı konmuş 68 hipertansiyonlu hasta ve 34 sağlıklı birey bu enine-kesitli gözlemsel çalışmaya alındı. ABİ maksimum ayak bileği kan basıncının brakiyal kan basıncına bölünmesi ile elde edildi. AVP inen aortanın başlangıcına konan renkli M-mod eğimi olarak kabul edildi.İstatistiksel analizde Student t-testi, Ki-kare testi, Pearson korelasyon ve lineer regresyon analizleri kullanıldı. Bulgular: Yaş, cinsiyet ve vücut kitle indeksi (VKİ) her iki grupta benzer bulundu. Kontrol grubuyla karşılaştırıldığında erken diyastolik hızının deselerasyon zamanı (184.0±32.2 ve 217.1±38.6, p

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Cite This Article

GÜNTEKİN, Ü., DEMİRBAĞ, R., GÜNEŞ, A., SEZEN, Y., YILDIZ, S., DEVECİ, E., YEŞİLAY, A. B., KAYA, Z., KAYA, B. C. (2022). Hipertansiyonlu hastalarda aortik akımın ilerleme hızı ile bilek-brakiyal indeksin ilişkisi: Gözlemsel bir çalışma. Anadolu Kardiyoloji Dergisi, Cilt: 12 - Sayı: 7, 568–573. https://ajindex.com/articles/436660

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