Journals / Anadolu Kardiyoloji Dergisi / 2007 / Cilt: 7 - Sayı: 3

Yeni tanı almış erişkin arteryel hipertansif hastalarda aortun elastik özellikleri ile QT dispersiyonu arasında ilişki

Relationship between the elastic properties of aorta and QT dispersion in newly diagnosed arterial adult hypertensives

Pages
275–280
Publication Date
2022-11-05
DOI
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Thus, we investigated whether QT dispersion (QTd), which is a reflection of ventricular repolarization inhomogeneity, is related to aortic elastic properties in patients with hypertension.Methods: Overall 113 patients with newly diagnosed hypertension and 25 normal control subjects were included in this cross-sectional case-controlled study.

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Objective & Hypothesis:Objective: Afterload is increased in hypertensive patients and increased afterload associated with both ventricular repolarization inhomogeneity and impaired elastic properties of aorta.
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Key Findings & Data:Thus, we investigated whether QT dispersion (QTd), which is a reflection of ventricular repolarization inhomogeneity, is related to aortic elastic properties in patients with hypertension.Methods: Overall 113 patients with newly diagnosed hypertension and 25 normal control subjects were included in this cross-sectional case-controlled study.
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Conclusion & Impact:Electrocardiograms were recorded in all subjects, and QTd and corrected QTd (cQTd) were then calculated.Results: Patients as compared with control subjects had lower mean AS and AD (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Afterload is increased in hypertensive patients and increased afterload associated with both ventricular repolarization inhomogeneity and impaired elastic properties of aorta. Thus, we investigated whether QT dispersion (QTd), which is a reflection of ventricular repolarization inhomogeneity, is related to aortic elastic properties in patients with hypertension.Methods: Overall 113 patients with newly diagnosed hypertension and 25 normal control subjects were included in this cross-sectional case-controlled study. Aortic strain (AS) and aortic distensibility (AD) were calculated echocardiographically from the derived ascending aorta diameters. Electrocardiograms were recorded in all subjects, and QTd and corrected QTd (cQTd) were then calculated.Results: Patients as compared with control subjects had lower mean AS and AD (p

Özet

Amaç: Hipertansif hastalarda art yük artmıştır ve artmış art yük hem ventriküler repolarizasyon eşitsizliğiyle (inhomogeneity); hem de aortanın bozulmuş elastik özellikleriyle ilişkilidir. Bu yüzden ventriküler repolarizasyon eşitsizliğini yansıtan QT dispersiyonunun (QTd) hipertansif hastalarda aortanın elastik özellikleriyle ilişkili olup olmadığını araştırmayı amaçladık. Yöntemler: Bu kros-seksiyonel vaka kontrollü çalışmaya hipertansiyon tanısını yeni almış 113 hastayla birlikte 25 sağlıklı kontrol grubu alındı. Aortanın esnekliği ve gerilimi çıkan aorta çaplarından ekokardiyografik olarak hesaplandı. Ekokardiyografi çalışmaya alınan tüm bireylere yapıldı. Ayrıca tüm bireylerin maksimum QT süreleri, minimum QT süreleri, QTd ve düzeltilmiş QTd (cQTd) hesaplandı.Bulgular: Kontrol grubuyla karşılaştırıldığında; hasta grubunun maksimum QT süresi, minimum QT süresi, QTd ve cQTd artmış olarak bulundu. Hasta grubuna çok değişkenli analiz yapıldığında; cQTd yaş, sol ventrikül kütle indeksi, aortanın gerilimi ve aortanın esnekliğiyle bağımsız olarak ilişkili bulundu (Sırasıyla; b=0.204, p=0.030, b=0.219, p=0.026, b=-0.238, p=0.021 ve b=-0.208, p=0.03). Ayrıca QTd da yaş (p=0.003) ve sol ventrikül kütle indeksi (p=0.008) yanında aortanın gerilimi (p=0.043) ve esnekliğiyle (p=0.037) bağımsız olarak ilişkili bulundu. Sonuç: Hipertansif hastalarda QTd ve cQTd artmıştır. Aortanın elastik özellikleri QTd ve cQTd üzerinde bir rol oynayabilir. (Anadolu Kardiyol Derg 2007; 7: 275-80)

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Cite This Article

YILDIZ, A., DEMİRBAĞ, R., YILMAZ, R., AKYOL, S., BAŞ, M., GÜR, M., POLAT, M. (2022). Yeni tanı almış erişkin arteryel hipertansif hastalarda aortun elastik özellikleri ile QT dispersiyonu arasında ilişki. Anadolu Kardiyoloji Dergisi, Cilt: 7 - Sayı: 3, 275–280. https://ajindex.com/articles/648472

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