Journals / Anadolu Kardiyoloji Dergisi / 2013 / Cilt: 13 - Sayı: 8

Polikistik over sendromu olan genç kadınlarda QT dispersiyonu ile gonadal hormonlar ve insülin arasındaki ilişki: Gözlemsel bir çalışma

Relationship of QT dispersion with sex hormones and insulin in young women with polycystic ovary syndrome: An observational study

Pages
772–777
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results were evaluated at the p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Polycystic ovary syndrome (PCOS) is a common endocrinopathy in reproductive women.
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Key Findings & Data:A total of 47 women, 25 patients with PCOS and 22 healthy, were included.
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Conclusion & Impact:The results were evaluated at the p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Polycystic ovary syndrome (PCOS) is a common endocrinopathy in reproductive women. Cardiovascular disease risk factors are more frequent in this population. We aimed in this study to investigate presence of QT dispersion and effects of sex hormones and insulin on QT duration in young PCOS patients. Methods: This present study was cross-sectional observational study. A total of 47 women, 25 patients with PCOS and 22 healthy, were included. Serum testosterone, estradiol and insulin levels were studied and electrocardiography was performed at 2nd or 3th days of menstrual cycle. The study population was divided into groups according to serum testosterone and estradiol levels. Sub-groups and pairwise groups were compared by Mann-Whitney U or student t-test. The associations of QTc durations with hormone levels were calculated using Spearman rank correlation analysis. The results were evaluated at the p

Özet

Amaç: Polikistik over sendromu (PKOS) reprodüktif dönemdeki kadınlarda sık karşılaşılan bir endokrinopatidir. PCOS hastalarında kardiyovas- küler hastalık risk faktörleri sık görülür. Bu çalışmada PCOS tanısı alan genç kadınlarda QT dispersiyonu varlığını ve gonadal hormonlar ve insülinin QT süresi üzerine etkilerini araştırmayı amaçladık. Yöntemler: Gözlemsel ve enine kesitli bu çalışmaya PKOS tanısı alan 25 hasta ve kontrol grubu olarak 22 sağlıklı olmak üzere toplam 47 kadın dahil edildi. Serum testosteron, östrojen ve insülin düzeyleri, elektrokardiyografik ölçümler menstrürasyon döngüsünün 2. veya 3. gününde yapıldı. HOMA-IR hesaplandı. Çalışma olguları östrojen ve testosteron düzeylerine göre gruplara ayrıldı. İkili grupların karşılaştırılmasında student-t veya Mann-Whitney U testi kullanıldı. Testosterone, östrojen, insülin ve HOMA-IR düzeyleri ile QT süreleri arasındaki ilişkinin değer- lendirilmesinde Spearman rank korelasyon analizi kullanıldı. P değeri

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Cite This Article

GAZİ, E., HANCI, V., KIRILMAZ, B., TEMİZ, A., ÖZTÜRK, U., GENCER, M., ÇAKIR, A. N. G., ALTUN, B. (2022). Polikistik over sendromu olan genç kadınlarda QT dispersiyonu ile gonadal hormonlar ve insülin arasındaki ilişki: Gözlemsel bir çalışma. Anadolu Kardiyoloji Dergisi, Cilt: 13 - Sayı: 8, 772–777. https://ajindex.com/articles/436206

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