Journals / Dicle Tıp Dergisi / 2016 / Cilt: 43 - Sayı: 1

Intestinal Perforation after Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case

Metastatik Kolon Kanseri Tedavisinde Bevacizumab Sonrası İnce Barsak Perforasyonu: Nadir Bir Olgu

Pages
168–170
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case report, we aimed to represent a 45 years old man who was diagnosed with intestinal per- foration after bevacizumab treatment ten months after a metastatic colon cancer surgery

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Bevacizumab is a monoclonal antibody which is targeting to vascular endothelial growth factor.
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Key Findings & Data:One should be aware of serious complications even though bevacizumab is a well-tolerated drug.
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Conclusion & Impact:In this case report, we aimed to represent a 45 years old man who was diagnosed with intestinal per- foration after bevacizumab treatment ten months after a metastatic colon cancer surgery
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Bevacizumab is a monoclonal antibody which is targeting to vascular endothelial growth factor. It has been shown to be a promising drug on metastatic colorectal cancer and is combined with chemotherapeutic agents. One should be aware of serious complications even though bevacizumab is a well-tolerated drug. There are a few in- testinal perforation cases that have been reported in the oncologic surgery literature related to the bevacizumab treatment. In this case report, we aimed to represent a 45 years old man who was diagnosed with intestinal per- foration after bevacizumab treatment ten months after a metastatic colon cancer surgery

Özet

Bevacizumab, vasküler endotelyal büyüme faktör mole- külünü hedef alan bir monoklonal antikordur. Metasta- tik kolorektal kanserlerde klinik ajan olarak umut verici olduğu gösterilmiştir. Metastatik kolorektal kanserlerde kemoterapötik ajanlar ile kombine kullanılmaktadır. Beva- cizumab iyi tolere edilebilen tedavi ajanlarından olmasına rağmen ciddi komplikasyonları açısından dikkatli olunma- lıdır. Literatürde olgu sunumları ile sınırlı az sayıda ince barsak perforasyonu bildirilmiştir. 45 yaşında metastatik kolon kanseri nedeniyle opere edilen ve bevacizumab te- davisi sonrası ince barsak perforasyonu gelişen olgumu- zu literatür eşliğinde sunmayı amaçladık

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Cite This Article

ÇETİN, D. A., GÜNDEŞ, E., ADAY, U., ÇİYİLTEPE, H., CUMHUR, K. D., DUMAN, M. (2016). Intestinal Perforation after Bevacizumab Treatment in Metastatic Colon Cancer: A Rare Case. Dicle Tıp Dergisi, Cilt: 43 - Sayı: 1, 168–170. https://ajindex.com/articles/349489

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