Journals / MN Kardiyoloji / 2009 / Cilt: 16 - Sayı: 2

Acute miyocardial infarction in a young man receiving combined chemotherapy for testicular cancer: Case report

Testiküler kanser tedavisi için kombine kemoterapi alan genç bir erkekte gelişen akut miyokard infarktüsü: Olgu sunumu

Pages
118–122
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present 35 year-old man whom miyocardial infarction developed two days after the first course of chemotherapy protocol including cisplatin, etoposide, bleomycin for testicular cancer and discuss this relationship in the light of the previously reported cases in the litareture.

📌 3 Key Takeaways

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Objective & Hypothesis:It is well known for a long time that chemotherapeutic agents can cause cardiotoxicity and some cardiovascular complications.
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Key Findings & Data:Cardiac events may include mild blood pressure changes, trombosis, arrhythmias, electrocardiographic changes, miyocarditis, pericarditis, cardiomyopathy, heart failure and miyocardial infarction.
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Conclusion & Impact:We present 35 year-old man whom miyocardial infarction developed two days after the first course of chemotherapy protocol including cisplatin, etoposide, bleomycin for testicular cancer and discuss this relationship in the light of the previously reported cases in the litareture.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Erişkin · Erkek · Miyokard enfarktüsü

Abstract

It is well known for a long time that chemotherapeutic agents can cause cardiotoxicity and some cardiovascular complications. Cardiac events may include mild blood pressure changes, trombosis, arrhythmias, electrocardiographic changes, miyocarditis, pericarditis, cardiomyopathy, heart failure and miyocardial infarction. We present 35 year-old man whom miyocardial infarction developed two days after the first course of chemotherapy protocol including cisplatin, etoposide, bleomycin for testicular cancer and discuss this relationship in the light of the previously reported cases in the litareture.

Özet

Kemoterapötik ajanların kardiyak toksisiteye ve bazı kardiyovaküler komplikasyonlara yol açtığı uzun yıllardır iyi bilinmektedir. Kardiyak olaylar, hafif-orta derecede tansiyon değişiklikleri, tromboz, aritmiler, elektrokardiyografik değişiklikler, miyokardit, perikardit, kardiyomiyopati, kalp yetmezliği ve miyokard infarktüsünü (Mİ) içerir. Bu vaka sunumunda, testiküler kanser nedeniyle sisplatin, etoposit ve bleomisinden oluşan kombine kemoterapi protokolünü 2 gün önce tamamladıktan sonra, akut miyokard infarktüsü geçiren 35 yaşında erkek hasta sunularak, bu birlikteliğin daha önce yayınlanmış literatür bilgileri ışığında tartışılması amaçlanmıştır.

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Cite This Article

BAYRAM, N. A., SARI, C., DURMAZ, T., KELEŞ, T., BAŞTUĞ, S., BOZKURT, E. (2009). Acute miyocardial infarction in a young man receiving combined chemotherapy for testicular cancer: Case report. MN Kardiyoloji, Cilt: 16 - Sayı: 2, 118–122. https://ajindex.com/articles/297483

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References (1)

  1. Pai V B: Nahata, M C Cardiotoxicity of chemotherapeutic agents: incidence, treatment and prevention Drug Saf 2000;2:263-302 2. Steffenelli Y, Kutzmits R, Ulrich W, Glogar D. Acute vascular toxicity ofter combination chemtherapy with cis-platin, vinblastine, ve bleomycin for testicular cancer Eur Heart J 1988;9:552-6 3.Swerdlow AJ, Higgins CD, Smith P, Cunningham D, Hancock BW, Horwich A et al. Miyocardial infarction mortality risk after treatment for Hodgin disease: a collaborative British cohort study. J Natl Cancerlnst 2007;99: 206-14 4.Janine N, Andries J, Jan van der M et al. Acute chemotherapy induced cardiovascular changes in patients with testicular cancer. J Clin. Oncol 2005:9130-7 5.Stoter G. Kopman A. Vendrik C.P et al: Ten year survival and late sequelae in testicular cancer patients treated with cisplatin, vinblastine, and bleomycin. J.Clin.Oncol.7 1989;7:1099-104 6.Hannun Y, Vugrin D: Long term survival in patients treated for testicular seminoma. J. Surg.Oncol. 1990; 43: 177-80 7.Bachmeyer C, Joly H, Jorest R. Early myocardial infarction during chemotherapy for testicular cancer. Tumori, 2000;86:428-30 8.Shoji S, Miyakita H, Shima M, Usui Y et al. Acute myocardial infarction during combined chemotherapy with belomycin,etoposide and cisplatin for testicular cancer. Hinyokika Kiyo, 2006;52:723-6 9.Iclı f, Karaoğuz H, Dincol D, et al. Severe vascular toxicity associated with cisplatin-based chemotherapy Cancer 1993;72:587-93 10.Licciardelo Jt, Moake Jl, Rudy CK et al.Elavetad plasma von Willwbrand factor levels and arterial occusive complications associated with cisplatin-basedchemotherapy. Oncology 1985;42:296-300 11.Schwarzer S, Eber B, Greinix H et al. llon Q wave myocardial infarction associated with bleomycin and etoposide chemotherapy. Eur Heart J 1991,12:748-50 12.Schecter JP, Jones SE, Jackson RA. Myocardial infarction in a 27 year old woman.-possible complication of treatment with VP-16-213(IISC 141540), mediastinal irradiation, or both (Letter). Cancer Chemther Rep 1975;59: 887-8 13.Om A, Ellahham S, Vetrovec GW. Radiation-induced coronary artery disease. Am Hearth J 1992;124:1598-602. 14.Viles-Gonzales JF, Anand SX, Valdiviezo C, Zafar MU, Hutter R, Sanz J, et al. Up date in atherothrombotic disease. MT Sinai J Med 2004;71:197-208