Journals / Güncel Retina Dergisi / 2017 / Cilt: 1 - Sayı: 1

Fundus Autofluorescence

Fundus Otoflöresans

Pages
46–56
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review summarizes fundus autofluorescence imaging of retinal diseases with supported by photographs of clinical cases in which differential diagnosis plays an important role

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Fundus autofluorescence imaging has been shown to be useful with regard to understanding of pathophysiologic mechanisms, diagnostics, phenotype-genotype correlation, identification of predictive markers for disease progression, and monitoring of novel therapies in retinal diseases.
📊
Key Findings & Data:Fundus autofluorescence imaging can be used in diagnosis and follow-up of many diseases.
💡
Conclusion & Impact:This review summarizes fundus autofluorescence imaging of retinal diseases with supported by photographs of clinical cases in which differential diagnosis plays an important role
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Fundus autofluorescence imaging has been shown to be useful with regard to understanding of pathophysiologic mechanisms, diagnostics, phenotype-genotype correlation, identification of predictive markers for disease progression, and monitoring of novel therapies in retinal diseases. Fundus autofluorescence imaging can be used in diagnosis and follow-up of many diseases. This review summarizes fundus autofluorescence imaging of retinal diseases with supported by photographs of clinical cases in which differential diagnosis plays an important role

Özet

Fundus otoflöresans görüntüleme, retina hastalıklarında patofizyolojik mekanizmaların anlaşılması, tanı, fenotipgenotip korelasyonu, hastalık progresyonunu etkileyen faktörlerin belirlenmesi ve tedavi monitörizasyonunda yararlı bir görüntüleme yöntemidir. Fundus otoflöresans görüntüleme birçok hastalığın tanı ve takibinde kullanılabilir. Bu derlemede fundus otoflöresans görüntülemenin retina hastalıkları ve ayırıcı tanısında önemli rol oynadığı hastalıklar klinik olgu fotoğraflarıyla da desteklenerek özetlenmiştir

🔖

Cite This Article

ŞERMET, F. (2017). Fundus Autofluorescence. Güncel Retina Dergisi, Cilt: 1 - Sayı: 1, 46–56. https://ajindex.com/articles/196210

References (13)

  1. von Rückmann A, Fitzke FW, Bird AC. Distribution of fundus autofluorescence with a scanning laser ophthalmoscope. Br J Ophthalmol 1995;79:407- 412
  2. Radu RA, Han Y, Bui TV, et al. Reductions in serum vitamin a arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases. Invest Ophthalmol Vis Sci 2005:46:4393-4401
  3. Lorenz B, Wabbels B, Wegscheider E, Hamel CP, Drexler W, Preising MN. Lack of fundus autofluorescence to 488 nanometers from childhood on in patients with early-onset severe retinal dystrophy associated with mutations in RPE65. Ophthalmology 2004;111:1585-1594
  4. Katz ML, Drea CM, Eldred GE, Hess HH, Robison WG. Influence of early photoreceptor degeneration on lipofuscin in the retinal pigment epithelium. Exp Eye Res 1986; 43:561-573
  5. Sparrow JR, Nakanishi K, Parish CA. The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. Invest Ophthalmol Vis Sci 2000;41(7):1981-9
  6. Sparrow JR, Cai B, Jang YP, Zhou J, Nakanishi K. A2E, a fluorophore of RPE lipofuscin, can destabilize membrane. Adv Exp Med Biol 2006;572:63-8
  7. Eldred GE, Katz ML. Fluorophores of the human retinal pigment epithelium: separation and spectral characterization. Exp Eye Res 1988;47:71–86
  8. Kitagawa K, Nishida S, Ogura Y. In vivo quantitation of autofluorescence in human retinal pigment epithelium. Ophthalmologica 1989;199:116–121
  9. Delori FC, Dorey CK, Staurenghi G, et al. In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophthalmol Vis Sci 1995;36:718–729
  10. Wabbels B, Demmler A, Paunescu K, et al. Fundus autofluorescence in children and teenagers with hereditary retinal diseases. Graefes Arch Clin Exp Ophthalmol 2006;244:36–45
  11. Bressler NM, Bressler SB. Preventative Ophthalmology. Age-related macular degeneration. Ophthalmology 1995;102:1206-1211
  12. International ARM Epidemiology Study Group. An international classification and grading system for age-related maculopathy and age-related macular degeneration. Surv Ophthalmol 1995;39:365-374
  13. Lois N, Owens SL, Coco R, et al. Fundus autofluorescence in patients with age-related macular degeneration and high risk of visual loss. Am J Ophthalmol. 2002;133(3):341-349, 14. von Ruckmann A, Fitzke FW, Bird AC. Fundus autofluorescence in age-related macular disease imaged with a laser scanning ophthalmoscope. Invest Ophthalmol Vis Sci.19