Journals / Retina-Vitreus / 2015 / Cilt: 23 - Sayı: 0

Fundus Autofluorescence To Whom? Why is that? Which Wavelength?

Fundus Otoflöresans Kime? Neden? Hangi Dalga Boyu?

Pages
1–7
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review summarizes various diseases that FAF imaging has an important role in the differential diagnosis

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Fundus autofluorescence (FAF) imaging has been shown to be useful with regard to understanding of pathophysiologic mechanisms, diagnostics, phenotype-genotype correlation, identification of predictive markers for disease progression, and monitoring of novel therapies in various dseases.
📊
Key Findings & Data:FAF imaging gives adjunctive information that obtained by fundus photography, fluorescein angiography, and optical coherence tomography.
💡
Conclusion & Impact:This review summarizes various diseases that FAF imaging has an important role in the differential diagnosis
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Fundus autofluorescence (FAF) imaging has been shown to be useful with regard to understanding of pathophysiologic mechanisms, diagnostics, phenotype-genotype correlation, identification of predictive markers for disease progression, and monitoring of novel therapies in various dseases. FAF imaging gives adjunctive information that obtained by fundus photography, fluorescein angiography, and optical coherence tomography. This review summarizes various diseases that FAF imaging has an important role in the differential diagnosis

Özet

Fundus otoflöresans (FOF) görüntüleme, çeşitli hastalıklarda patofizyolojik mekanizmaların anlaşılması, tanı, fenotip-genotip korelasyonu, hastalık progresyonunu etkileyen faktörlerin belirlenmesi ve tedavi monitörizasyonunda yararlı bir görüntüleme yöntemidir. Fundus fotoğrafı, flöresein anjiografi ve optik koherens tomografiye ilave bilgiler verir. Bu derlemede FOF'un ayırıcı tanıda önemli rol oynadığı hastalıklar özetlenmiştir

🔖

Cite This Article

ŞERMET, F. (2015). Fundus Autofluorescence To Whom? Why is that? Which Wavelength?. Retina-Vitreus, Cilt: 23 - Sayı: 0, 1–7. https://ajindex.com/articles/304985

References (14)

  1. Von Rückmann A, Fitzke FW, Bird AC. Distrubution of fundus auto- fluorescencewith a scanning laser ophthalmoscope. Br J Ophthalmol 1995;79:407-12.
  2. Delori FC, Dorey CK, Staurenghi G, et al. In vivo fluorescence of the ocu- lar fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophthalmol and Visual Sci 1995;36:718-29.
  3. Delori FC, Goger DG, Dorey CK. Age-related accumulation and spatial distribution of lipofuscin in RPE of normal subjects. Invest Ophthalmol Vis Sci 2001;42:1855-66.
  4. Davies S, Elliot MH, Floor E, et al. Photocytotoxicity of lipofuscin in hu- man retinal pigment epithelial cells. Free Radic Biol Med 2001;31:256-65.
  5. Eldred GE, Katz ML. Fluorophores of the human retinal pigment epitheli- um: separation and spectral characterization. Exp Eye Res 1988;47:71-86.
  6. Lamb LE, Simon JD. A2E:A component of lipofuscin. Photochem Photo- biol 2004;79:127-36.
  7. Kitagawa K, Nishida S, Ogura Y. In vivo quantitation of autofluorescence in human retinal pigment epithelium. Ophthalmologica 1989;199:116-21.
  8. Delori FC, Dorey CK, Staurenghi G, et al. In vivo fluorescence of the ocu- lar fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophthalmol Vis Sci 1995;36:718-729.
  9. Von Rückmann A, Fitzke FW, Bird AC. Distrubution of fundus auto- fluorescence with a scanning laser ophthalmoscope. Br J Ophthalmol 1995;79:407-12.
  10. Keilhauer CN, Delori FC. Near-infrared autofluorescence imaging of the fundus visualization of oclar melanin. Invest Ophthalmol Vis Sci 2006;47:3556-64.
  11. Neetens A, Burvenich H. Autofluorescence of optic disc drusen. Bull Soc Belge Ophthalmol1077;179:103-10.
  12. Bakall B, Radu RA, Stanton JB, et al. Enhanced accumulation of A2E in individuals homozygous or heterozygous for mutations in BEST1 (VMD2). Exp Eye Res 2007;85:34-43.
  13. Zhuk SA, Edwards AO. Peripherin/RDS and VMD2 mutations in macular dystrophies with adult-onset vitelliform lesion. Mol Vis 2006;12:811-5.
  14. Sodi A, Bini A, Passerini I, et al. Different patterns of fundus autofluores- cence related to ABCA4 gene mutations in Stargardt disease. Ophthalmic Surg Lasers Imaging 2010;41:48-53.