AI Summary & Key Takeaways
AI InsightTo achieve the best results in clinical practice, en face flow maps should be evaluated together with B-scan SD-OCT images.
📌 3 Key Takeaways
Abstract
Objectives: To evaluate the vascular changes of idiopathic macular telangiectasia type 2 (MacTel 2) patients with optical coherencetomography angiography (OCTA) and correlate these changes with the findings of spectral domain optical coherence tomography (SD-OCT).Materials and Methods: Simultaneous SD-OCT and OCTA images of 10 eyes of 6 patients who were diagnosed as MacTel 2 inAnkara University Faculty of Medicine, Department of Ophthalmology were obtained and graded according to the OCTA grading systemfor MacTel 2.Results: Ten eyes of 6 patients were included. Four (66%) patients were female and 2 (34%) were male. The disease was grade 0 in 2 eyes,grade 1 in 2 eyes, grade 2 in 3 eyes, grade 3 in 1 eye, grade 4 in 1 eye, and grade 5 in 1 eye. The most common findings in grade 1, 2, and 3non-proliferative disease were thinning of the outer retinal layers, presence of intraretinal hyporeflective layers and inner limiting membranedraping. In cases with subretinal choroidal neovascularisation (CNV) in OCTA, CNV or CNV scar was present in the B-scan SD-OCT images.In a case in which OCT was within normal limits, vascular changes consistent with grade 1 disease were observed in OCTA. On the contrary,2 patients with significant foveal atrophy and macular hole in B-scan showed changes of early disease in OCTA. In some of the eyes, OCTArevealed an intact superficial vascular layer despite visible changes in the deep layer and the presence of neovascularisation.Conclusion: OCTA yields findings which are important for understanding the pathogenesis of the disease and providing better follow-up.Contrary to fundus fluorescein angiography, changes in the deep arterial plexus in the early disease and CNV can be clearly observed withOCTA. To achieve the best results in clinical practice, en face flow maps should be evaluated together with B-scan SD-OCT images.