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Journals / Journal of advances in vetbio science and techniques / 2026 / Volume: 9 Issue: 2

The effect of ginger essential oil (Zingiber officinale) on catalase in rat kidney tissue

Yağmur Yıldız Asker(KAFKAS ÜNİVERSİTESİ)0000-0003-0635-0098
Şükran Aras(KAFKAS ÜNİVERSİTESİ)0000-0002-3267-5251
Mükremin Ölmez(KAFKAS ÜNİVERSİTESİ)0000-0002-5003-3383
Hasan Asker(UŞAK ÜNİVERSİTESİ)0000-0002-5703-2164
Mustafa Makav(KAFKAS ÜNİVERSİTESİ)0000-0003-1879-8180
Arzu Gezer(ATATÜRK ÜNİVERSİTESİ)0000-0002-1658-2098
Tarkan Şahin(KAFKAS ÜNİVERSİTESİ)0000-0003-0155-2707
Pages
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Publication Date
2024-08-22
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We think that ginger essential oil can be used in appropriate doses and times to reduce kidney damage caused by oxidative stress in the kidney.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:We were aimed to investigate the effect of ginger essential oil (Zingiber officinale) on catalase release in rat kidney tissue by histopathological and immunohistochemically method.
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Key Findings & Data:This study, 21 male Wistar albino rats were used.
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Conclusion & Impact:We think that ginger essential oil can be used in appropriate doses and times to reduce kidney damage caused by oxidative stress in the kidney.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Catalase · ginger essential oil · kidney

Abstract

We were aimed to investigate the effect of ginger essential oil (Zingiber officinale) on catalase release in rat kidney tissue by histopathological and immunohistochemically method. This study, 21 male Wistar albino rats were used. Rats were divided into three groups: control, 100 mg/kg ginger essential oil (G100), and 500 mg/kg ginger essential oil (G500). Hematoxylin-eosin staining method was used for histopathological evaluations. Immunohistochemically localization of catalase in kidney tissue was determined by streptavidin-biotin peroxidase method. As a result of histopathological evaluations, an increase in glomerulus diameter was observed in kidney tissues of G100 and G500 groups. In addition, vacuolar degeneration was observed in the proximal and distal tubule epithelial cells in the renal cortex of the G100 group. The immunoreactivity of catalase in the renal cortex region; In the control group, it is strong in the proximal tubules and weak in the mesangial cells. While moderate severity in the proximal tubules and weak in the mesangial cells in the G100 group, very weak catalase immunoreactivity was observed in the G500 group. Strong catalase immunoreactivity was detected in the proximal and collecting ducts of the kidney medulla regions of the rats in all groups. We think that ginger essential oil can be used in appropriate doses and times to reduce kidney damage caused by oxidative stress in the kidney.

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Cite This Article

Asker, Y. Y., Aras, Ş., Ölmez, M., Asker, H., Makav, M., Gezer, A., Şahin, T. (2024). The effect of ginger essential oil (Zingiber officinale) on catalase in rat kidney tissue. Journal of advances in vetbio science and techniques, Volume: 9 Issue: 2. https://doi.org/10.31797/vetbio.1415244

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