Dergiler / Journal of Experimental and Clinical Medicine / 2013 / Cilt: 30 - Sayı: 4

Levels of serum trace elements in ischemic stroke patients

Sayfa
301–304
Yayın Tarihi
2014-02-04
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The results of our study show that an increase in the levels of Cd, Pb, Co and Cu may be important in the occurrence of IS.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:The mortality and morbidity of ischemic stroke (IS) can be decreased by early diagnosis and proper treatment of these patients in the emergency department.
📊
Temel Bulgular & Veri:In this prospective study, serum copper (Cu), lead (Pb), cadmium (Cd), zinc (Zn), cobalt (Co), manganese (Mn), and magnesium (Mg) levels were investigated in 25 healthy participants (control group) and 24 IS patients.
💡
Sonuç & Katkı:The results of our study show that an increase in the levels of Cd, Pb, Co and Cu may be important in the occurrence of IS.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Emergency department · Heavy metal · Ischemic stroke

Abstract

The mortality and morbidity of ischemic stroke (IS) can be decreased by early diagnosis and proper treatment of these patients in the emergency department. The levels of trace elements in the human body are important in maintaining the balance in the various biological components. In this study, we examined the impact of imbalance in levels of trace elements in patients with acute IS. In this prospective study, serum copper (Cu), lead (Pb), cadmium (Cd), zinc (Zn), cobalt (Co), manganese (Mn), and magnesium (Mg) levels were investigated in 25 healthy participants (control group) and 24 IS patients. The Cd, Pb, Co, and Cu levels were significantly higher in the patients compared to control groups (P<0.05), while the levels of Zn, Mg, Mn were lower. The results of our study show that an increase in the levels of Cd, Pb, Co and Cu may be important in the occurrence of IS.

🔖

Bu Makaleye Atıf Yap

GÖNÜLLÜ, H., KARADAŞ, S., MİLANLİOĞLU, A., GÖNÜLLÜ, E., KATI, C., DEMİR, H. (2014). Levels of serum trace elements in ischemic stroke patients. Journal of Experimental and Clinical Medicine, Cilt: 30 - Sayı: 4, 301–304. https://ajindex.com/articles/678491

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (15)

  1. Akarachkova, E.S., Vershinina, S.V., Kotova, O.V., 2012. Magnesium in the treatment and prevention of cerebrovascular disease. Kardiologiia. 52, 80-86.
  2. Altamura, C., Squitti, R., Pasqualetti, P., Gaudino, C., Palazzo, P., Tibuzzi, F., Lupoi, D., Cortesi, M., Rossini, P.M., Vernieri, F., 2009. Ceruloplasmin/Transferrin system is related to clinical status in acute stroke. Stroke. 40, 1282-1288.
  3. Atasoy, N., Mercan, U., Alacabey, İ., Kul, A.R., 2011. Levels of heavy metals and certain macro elements in potable and tap water at Van city center. Hacettepe J. Biol. & Chem. 39, 391-396.
  4. Bradbury, M.W., 1992. An approach to study of transport of trace metals at the blood-brain barrier. Prog. Brain Res. 91, 133-138.
  5. Burnet, F.M., 1981. A possible role of zinc in the pathology of dementia. Lancet. 24, 186-188.
  6. Cebi, A., Kaya, Y., Gungor, H., Demir, H., Yoruk, I.H., Soylemez, N., Gunes, Y., Tuncer, M., 2011. Trace elements, heavy metals and vitamin levels in patients with coronary artery disease. Int. J. Med. Sci. 8, 456-460.
  7. Cocco, P., Dosemeci, M., Heineman, E.F., 1988. Brain cancer and occupational exposure to lead. J. Occup. Environ. Med. 40, 937-942.
  8. Dexter, D.T., Wells, F.R., Lees, A.J., Agid, F., Agid, Y., Jenner, P., Marsden, C.D., 1989. Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson’s disease. J. Neurochem. 52, 1830-1836.
  9. Donma, O., Donma, M.M., 2002. Association of headaches and the metals. Biol. Trace. Elem. Res. 90, 1-14.
  10. Emre, U., Durukan, A., Tatlısumak, T., 2007. Emergency management of acute ischemıc stroke. Turkiye Klinikleri, J. Surg. Med. Sci. 3, 6-12.
  11. Goldman, R.S., Finkbeiner, S.M., 1988. Therapeutic use of magnesium sulfate in selected cases of cerebral ischemia and seizure. N. Engl. J. Med. 319, 1224-1225.
  12. Hankey, G.J., 2006. Potential new risk factors for ischemic stroke: What is their potential?. Stroke. 37, 2181-2188.
  13. Herrmann, M., Vos, P., Wunderlich, M.T., de Bruijn, C.H., Lamers, K.J., 2000. Release of glial tissue-specific proteins after acute stroke: A comparative analysis of serum concentrations of protein S-100b and glial fibrillary acidic protein. Stroke. 31, 2670-2677.
  14. Imai, N., Okabe, T., 2011. Kinetics differ between copper-zinc and manganese superoxide dismutase activity with acute ischemic stroke. J. Stroke Cerebrovasc. Dis. 20, 75-78.
  15. Larsen, N.A., Pakkenberg, H., Damsgard, E., Deydorm, K., Wold, S., 1981. Distribution of arsenic, manganese, and selenium in the human brain in c