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Dergiler / Turkish Journal of Chemistry / 2018 / Cilt: 42 - Sayı: 6

Recent synthetic methodologies for pyrimidine and its derivatives

Matloob AHMAD
Farhat IBRAHEEM
Furqan Ahmad SADDIQUE
Asim MANSHA
Sana ASLAM
Tahir FAROOQ
Sayfa
1421–1458
Yayın Tarihi
2022-11-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In this context, the present reviewillustrates a variety of novel and efficient synthetic approaches towards the synthesis of pyrimidine and its derivativesthat were reported recently.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Pyrimidine derivatives are well known due to their remarkable pharmacological potential in various fields ofscience, and they are also present in some natural substances like DNA and RNA.
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Temel Bulgular & Veri:These scaffolds manifest diversifiedbiological activities such as antimicrobial, antiinflammatory, anti-HIV, antitubercular, antitumor, antineoplastic, andantimalarial.
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Sonuç & Katkı:In this context, the present reviewillustrates a variety of novel and efficient synthetic approaches towards the synthesis of pyrimidine and its derivativesthat were reported recently.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Pyrimidine derivatives are well known due to their remarkable pharmacological potential in various fields ofscience, and they are also present in some natural substances like DNA and RNA. These scaffolds manifest diversifiedbiological activities such as antimicrobial, antiinflammatory, anti-HIV, antitubercular, antitumor, antineoplastic, andantimalarial. A pyrimidine ring is constructed when chalcones, amidines, guanidine, nitriles, isocyanates, urea, thiourea,and aminopyrazoles undergo condensation, coupling, or cyclization reactions. In this context, the present reviewillustrates a variety of novel and efficient synthetic approaches towards the synthesis of pyrimidine and its derivativesthat were reported recently.

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Bu Makaleye Atıf Yap

AHMAD, M., IBRAHEEM, F., SADDIQUE, F. A., MANSHA, A., ASLAM, S., FAROOQ, T. (2022). Recent synthetic methodologies for pyrimidine and its derivatives. Turkish Journal of Chemistry, Cilt: 42 - Sayı: 6, 1421–1458. https://ajindex.com/articles/601821

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