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Yapay Zeka Hızlı Bakış & Çıkarımlar
AI Insight⚡ TL;DR(1 Cümlede Hızlı Çıkarım)
The resulting thiophene was tested in the MTT assay for its cytotoxic activity against HL 60 cells.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:The thiophene analogue of (\pm)-4-ipomeanol (1) was prepared in 2 steps starting from 3-iodothiophene and pent-4-yn-2-ol.
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Temel Bulgular & Veri:The key steps were a Sonogashira reaction, followed by HgO catalysed hydratisation of the triple bond.
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Sonuç & Katkı:The resulting thiophene was tested in the MTT assay for its cytotoxic activity against HL 60 cells.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Sonogashira reaction · 4-ipomeanol · cytotoxic activity
Özet
The thiophene analogue of (\pm)-4-ipomeanol (1) was prepared in 2 steps starting from 3-iodothiophene and pent-4-yn-2-ol. The key steps were a Sonogashira reaction, followed by HgO catalysed hydratisation of the triple bond. The resulting thiophene was tested in the MTT assay for its cytotoxic activity against HL 60 cells.
Abstract
The thiophene analogue of (\pm)-4-ipomeanol (1) was prepared in 2 steps starting from 3-iodothiophene and pent-4-yn-2-ol. The key steps were a Sonogashira reaction, followed by HgO catalysed hydratisation of the triple bond. The resulting thiophene was tested in the MTT assay for its cytotoxic activity against HL 60 cells.
Anahtar kelimeler
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Bu Makaleye Atıf Yap
KRAUSS, J., UNTERREITMEIER, D., BRACHER, F. (2006). Short and Effective Synthesis of a Thiophene Analogue of (\pm)-4-Ipomeanol and Its Biological Evaluation. Turkish Journal of Chemistry, Cilt: 30 - Sayı: 4, 451–454. https://ajindex.com/articles/184894