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Dergiler / Turkish Journal of Chemistry / 2005 / Cilt: 29 - Sayı: 6

A new approach towards $(pm)$-4-ipomeanol and its 2-furyl regioisomer

Jürgen KRAUSS
Franz BRACHER
Doris UNTERREITMEIER
Sayfa
635–639
Yayın Tarihi
2022-11-05
DOI
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The resulting compounds were tested in an agar diffusion assay against several bacteria and fungi, but did not show significant activity.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The cytotoxic furan derivative $(pm)$-4-ipomeanol (1) and its regioisomer (8) were prepared in a new and efficient way starting from commercially available furan derivatives.
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Temel Bulgular & Veri:In both cases the key step was a regioselective solvolysis of the terminal double bond with trifluoroacetic anhydride and boron trifluoride.
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Sonuç & Katkı:The resulting compounds were tested in an agar diffusion assay against several bacteria and fungi, but did not show significant activity.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

The cytotoxic furan derivative $(pm)$-4-ipomeanol (1) and its regioisomer (8) were prepared in a new and efficient way starting from commercially available furan derivatives. In both cases the key step was a regioselective solvolysis of the terminal double bond with trifluoroacetic anhydride and boron trifluoride. The resulting compounds were tested in an agar diffusion assay against several bacteria and fungi, but did not show significant activity.

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Bu Makaleye Atıf Yap

KRAUSS, J., BRACHER, F., UNTERREITMEIER, D. (2022). A new approach towards $(pm)$-4-ipomeanol and its 2-furyl regioisomer. Turkish Journal of Chemistry, Cilt: 29 - Sayı: 6, 635–639. https://ajindex.com/articles/602224

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