Dergiler / Turkish Journal of Chemistry / 2017 / Cilt: 41 - Sayı: 3

Stereoselective and regioselective synthesis of $N$-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates

Sayfa
323–334
Yayın Tarihi
2017-06-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The targeted $N$-substituted azole acrylates were efficiently obtained in good yields (39%-89%).

📌 3 Maddede Bu Makale

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Amaç & Hipotez:$N$-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis--Hillman acetates and a suitable acylazole in the presence of K$_{2}$CO$_{3}$ as a base catalyst.
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Temel Bulgular & Veri:$N$-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis--Hillman acetates and a suitable acylazole in the presence of K$_{2}$CO$_{3}$ as a base catalyst.
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Sonuç & Katkı:The targeted $N$-substituted azole acrylates were efficiently obtained in good yields (39%-89%).
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Imidazole · benzimidazole · benzotriazole

Abstract

$N$-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis--Hillman acetates and a suitable acylazole in the presence of K$_{2}$CO$_{3}$ as a base catalyst. The targeted $N$-substituted azole acrylates were efficiently obtained in good yields (39%-89%).

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Bu Makaleye Atıf Yap

ÖZENÇ, A. K., ÇELİK, İ., KÖKTEN, Ş. (2017). Stereoselective and regioselective synthesis of $N$-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates. Turkish Journal of Chemistry, Cilt: 41 - Sayı: 3, 323–334. https://ajindex.com/articles/184353

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