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AI Summary & Key Takeaways
AI Insight⚡ TL;DR(Too Long; Didn't Read)
The targeted $N$-substituted azole acrylates were efficiently obtained in good yields (39%-89%).
📌 3 Key Takeaways
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Objective & Hypothesis:$N$-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis--Hillman acetates and a suitable acylazole in the presence of K$_{2}$CO$_{3}$ as a base catalyst.
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Key Findings & Data:$N$-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis--Hillman acetates and a suitable acylazole in the presence of K$_{2}$CO$_{3}$ as a base catalyst.
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Conclusion & Impact:The targeted $N$-substituted azole acrylates were efficiently obtained in good yields (39%-89%).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Imidazole · benzimidazole · benzotriazole
Abstract
$N$-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis--Hillman acetates and a suitable acylazole in the presence of K$_{2}$CO$_{3}$ as a base catalyst. The targeted $N$-substituted azole acrylates were efficiently obtained in good yields (39%-89%).
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Cite This Article
ÖZENÇ, A. K., ÇELİK, İ., KÖKTEN, Ş. (2017). Stereoselective and regioselective synthesis of $N$-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates. Turkish Journal of Chemistry, Cilt: 41 - Sayı: 3, 323–334. https://ajindex.com/articles/184353