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AI InsightBu çalışmada, ilk olarak başlangıç maddesi olan etil 1-(4-bromofenil)-2-(1,3,5-trifenil-1H-pirazol-4-(5H)-
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Özet
Bu çalışmada, ilk olarak başlangıç maddesi olan etil 1-(4-bromofenil)-2-(1,3,5-trifenil-1H-pirazol-4-(5H)-
Abstract
In this study, firstly, ethyl 1-(4-bromophenyl)-2-(1,3,5-triphenyl-1H-pyrazol-4-(5H)-ylidene) hydrazine (1), which has starting material, was synthesized. A series of new 1H-pyrazol-4-yl diazene (2a-h) derivatives were synthesized from reaction the obtained starting material and various hydrazines. The synthesized compounds were confirmed by spectral methods such as elemental analysis, IR and NMR. Antibacterial activity of the compounds were investigated by disc diffusion method against to Gram (+) and Gram (-) bacteria. Gentamicin and Cefotaxime antibiotics were used as the control group. None of the doses showed any antibacterial activity compared to the control.