Journals / Journal of advances in vetbio science and techniques / 2023 / Cilt: 8 Sayı: 1

A study of lipid and protein profiles and liver enzyme levels in neonatal diarrhea calves based on clinical severity of the disease

Pages
1–8
Publication Date
2023-04-30
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The current study concluded that there was no change in the protein profile in calves with neonatal diarrhea, but the lipid profile was negatively affected and liver function was impaired, and the impairment in liver function increased as the clinical severity of the disease increased.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The purpose of this study was to investigate the serum lipid and protein profile as well as liver enzyme levels in neonatal calves with diarrhea.
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Key Findings & Data:The study included 40 calves, 30 with diarrhea and 10 healthy (control).
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Conclusion & Impact:The current study concluded that there was no change in the protein profile in calves with neonatal diarrhea, but the lipid profile was negatively affected and liver function was impaired, and the impairment in liver function increased as the clinical severity of the disease increased.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Calf diarrhea · liver enzymes · lipid profile

Abstract

The purpose of this study was to investigate the serum lipid and protein profile as well as liver enzyme levels in neonatal calves with diarrhea. The study included 40 calves, 30 with diarrhea and 10 healthy (control). Calves with diarrhea were divided into three groups based on clinical findings: mild, moderate, and severe. Blood samples were taken from the vena jugularis after routine clinical examinations of the calves to determine the lipid profile, protein profile, liver enzyme levels, and glucose levels. Serum total cholesterol (TC) (P<0.01), HDL (P<0.01), and LDL (P<0.05) levels were all found to be lower in the calves in the mild, moderate, and severe groups compared to the control group. No significant difference in TP and ALB values was found between the groups. Additionally, serum aspartate aminotransferase (AST) (P<0.01), alkaline phosphatase (ALP), and glucose (P<0.05) levels were also greater in calves with diarrhea compared to the control group. The current study concluded that there was no change in the protein profile in calves with neonatal diarrhea, but the lipid profile was negatively affected and liver function was impaired, and the impairment in liver function increased as the clinical severity of the disease increased.

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Cite This Article

DEĞİRMENÇAY, Ş., AKTAŞ, M. S., HANEDAN, B., KIRBAŞ, A., ULAŞ, N., YANAR, E., AYDIN, Ö., EREN, E., EROĞLU, M. S. (2023). A study of lipid and protein profiles and liver enzyme levels in neonatal diarrhea calves based on clinical severity of the disease. Journal of advances in vetbio science and techniques, Cilt: 8 Sayı: 1, 1–8. https://ajindex.com/articles/930108

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References (9)

  1. Akgün, S., Ertel, N. H., Mosenthal, A., & Oser, W. (1998). Postsurgical reduction of serum lipoproteins: Interleukin-6 and the acute-phase response. Journal of Laboratory and Clinical Medicine, 131: 103-108. DOI: 10.1016/s0022-2143(98)90083-x Al-Alo, K. Z. K., Nikbakht Brujeni, G., Lotfollahzadeh, S., Moosakhani, F., & Gharabaghi, A. (2018). Correlation between neonatal calf diarrhea and the level of maternally derived antibodies. Iranian Journal of Veterinary Research, 19(1), 3-8
  2. Albayrak, H., & Kabu, M. (2016). Determining serum haptoglobin and cytokine concentrations in diarrheic calves. Fırat University Veterinary Journal of Health Sciences, 30 (2), 113-117.
  3. Alvarez, C., & Ramos, A. (1986). Lipids, lipoproteins, and apoproteins in serum during infection. Clinical Chemistry, 32 (1 Pt 1): 142-145.
  4. Anderson, N. L., & Anderson, N. G. (2002). The human plasma proteome. Molecular and Cellular Proteomics, 1(11), 845-867. DOI: 10.1074/mcp.r200007-mcp200 Arfuso, F., Fazio, F., Panzera, M., Giannetto, C., di Pietro, S., Giudice, E., & Piccione, G. (2017). Lipid and lipoprotein profile changes in newborn calves in response to the perinatal period. Acta Veterinaria Beograd, 67 (1), 25-32. https://doi.org/10.1515/acve-2017-0003
  5. Athanasiou, L. V., Katsoulos, P. D., Ziogas, C., Kassab, A., & Polizopoulou, Z. (2019). Serum protein electrophoretic profile in diarrheic neonatal calves. Comparative Clinical Pathology, 28 (3), 685-688. https://doi.org/10.1007/s00580-019-02935-w
  6. Aydogdu, U., Coskun, A., Yildiz, R., Guzelbektes, H., & Sen, I. (2018). Clinical importance of lipid profile in neonatal calves with sepsis. The Journal of the Hellenic Veterinary Medical Society, 69 (4), 1189-1194. https://doi.org/10.12681/jhvms.15926
  7. Ballou, M. A., Cobb, C. J., Hulbert, L. E., & Carroll, J. A. (2011). Effects of intravenous Escherichia coli dose on the pathophysiological response of colostrum-fed Jersey calves. Veterinary Immunology and Immunopathology, 141 (1–2), 76–83. DOI: 10.1016/j.vetimm.2011.02.008. Barati, M., Nazari, M. Z., Taher, M.T., & Farhadi, N. (2011). Comparison of lipid profile in septic and non-septic patients. Iranian Journal of Clinical Infectious Diseases, 6 (4), 144-147.
  8. Bartosz, J., & Katarzyna, A. (2016). Application of native agarose gel electrophoresis of serum proteins in veterinary diagnostics. Journal of Veterinary Research, 60: 501–508. DOI: 10.1515/jvetres-2016-0074
  9. Başer, D. F., & Civelek, T. (2013). Correlations between venous acid-base status and