Journals / The Turkish Journal of Ear Nose and Throat / 2006 / Cilt: 16 - Sayı: 2

Prognostic factors and survival rates in oral cavity cancers

Oral kavile kanserlerinde prognostik faktörler ve sağkalım oranları

Pages
64–71
Publication Date
2006-03-20
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Age, sex, tumor differentiation, and the total radiotherapy dose were not found to affect survival p>0.05 , whereas tumor size, positive lymph nodes, stage, and treat­ ment modality were found as significant prognostic factors p=0.01 .Conclusion: Our data show that tumor size, lymph node involvement, stage, and postoperative adju­ vant radiotherapy are significant parameters that affect survival in oral cavity cancers.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: We evaluated the treatment results and prognostic factors that might affect local control and survival in patients receiving radiotherapy for oral cavity cancers.Patients and Methods: The study included 32 patients 16 men, 16 women; mean age 62 years; range 26 to 90 years who received radiotherapy for oral cavity can­ cers.
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Key Findings & Data:AH the patients had squamous celi carcinoma, which involved the tongue in 15 patients 46.9% and the lower lip in 13 patients 40.6% .
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Conclusion & Impact:Age, sex, tumor differentiation, and the total radiotherapy dose were not found to affect survival p>0.05 , whereas tumor size, positive lymph nodes, stage, and treat­ ment modality were found as significant prognostic factors p=0.01 .Conclusion: Our data show that tumor size, lymph node involvement, stage, and postoperative adju­ vant radiotherapy are significant parameters that affect survival in oral cavity cancers.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Karsinom · skuamöz hücreli/radyoterapi/cerrahi · ağız neoplazileri/radyoterapi/cerrahi

Abstract

Objectives: We evaluated the treatment results and prognostic factors that might affect local control and survival in patients receiving radiotherapy for oral cavity cancers.Patients and Methods: The study included 32 patients 16 men, 16 women; mean age 62 years; range 26 to 90 years who received radiotherapy for oral cavity can­ cers. AH the patients had squamous celi carcinoma, which involved the tongue in 15 patients 46.9% and the lower lip in 13 patients 40.6% . Most of the patients n=21,65.7% had or T2 tumors. Neck lymph nodes were positive in 11 patients 34.4% . Fifteen patients had early stage stage I, II , 17 patients had advanced stage stage III, IV tumors. Sixteen patients received primary radiotherapy and 16 patients received postop- erative adjuvant radiotherapy, with doses ranging from 5000 cGy to 7000 cGy. The mean follow-up period was 68 months range 5 to 147 months .Results: Two-year and five-year survival rates were 53% and 39%, respectively. Age, sex, tumor differentiation, and the total radiotherapy dose were not found to affect survival p>0.05 , whereas tumor size, positive lymph nodes, stage, and treat­ ment modality were found as significant prognostic factors p=0.01 .Conclusion: Our data show that tumor size, lymph node involvement, stage, and postoperative adju­ vant radiotherapy are significant parameters that affect survival in oral cavity cancers.

Özet

Amaç: Oral kavite kanseri tanısıyla radyoterapi uygulanan hastalarda tedavi sonuçları, lokal kontrol vesağkalımı etkileyebilecek prognostik faktörler değerlendirildi.Hastalar ve Yöntemler: Oral kavite kanseri nedeniyle radyoterapi uygulanan 32 hasta çalışmaya alındı.Tüm hastalarda tümör yassı hücreli karsinomdu.On beş hastada %46.9 dil, 13 hastada %40.6 altdudak kanseri vardı. Hastaların çoğu T1, T2tümörle 21 hasta, %65.7 başvurmuştu; 11’inde %34.4 boyun lenf nodları pozitifti. On beş hasta erken evre evre I, II , 17 hasta ileri evredeydi evre III, IV .On altı hasta primer radyoterapi, 16 hasta ameliyatsonrası adjuvan radyoterapi ile tedavi görmüştü.Radyoterapi dozu 5000-7000 cGy arasında değişiyordu. Hastaların ortalama takip süresi 68 ay dağılım 5-147 ay idi.Bulgular: İki yıllık ve beş yıllık sağkalım oranları sırasıyla %53 ve %39 olarak hesaplandı. Yaş, cinsiyet, tümör diferansiasyonu ve toplam radyoterapidozunun sağkalımı anlamlı olarak etkilemediği görüldü p>0.05 . Tümör büyüklüğü, boyun lenf nodututulumu, evre ve tedavi yönteminin sağkalımı anlamlı etkilediği görüldü p=0.01 . Sonuç: Çalışmamızda tümör büyüklüğü, lenf nodututulumu, evre ve ameliyat sonrası adjuvan radyoterapi, oral kavite kanserlerinde sağkalımı anlamlı olarak etkileyen faktörler olarak bulundu

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Cite This Article

ÖZYURT, S. C., UĞURLUER, G., AKSARAY, F., ASLAN, N., HABİBOĞLU, R., TÜMÖZ, M. (2006). Prognostic factors and survival rates in oral cavity cancers. The Turkish Journal of Ear Nose and Throat, Cilt: 16 - Sayı: 2, 64–71. https://ajindex.com/articles/727204

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