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Journals / KONURALP TIP DERGİSİ / 2021 / Cilt: 13 - Sayı: S1

Thiol-Disulphide Homoeostasis in COVID-19: Evaluation of its Relationship with Complete Blood Count Parameters

COVID-19'da Tiyol-Disülfid Dengesi: Tam Kan Sayımı Parametreleri ile İlişkisinin Değerlendirilmesi

Mehmet Ramazan ŞEKEROĞLU
Erdem ÇOKLUK
Selcuk YAYLACI
Ali Fuat ERDEM
Fatıma Betül TUNCER
Hamad DHEİR
Ertuğrul GÜÇLÜ
Aziz ÖĞÜTLÜ
Deniz ÇEKİÇ
Abdülkadir AYDIN
Fatma Behice SERİNKAN CİNEMRE
Pages
460–467
Publication Date
2021-08-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

TT, NT, DD and lymphocyte levels of COVID-19 patients treated in medical floor were higher than those treated in intensive care unit; WBC, neutrophil and NLR were low(P

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, we aimed to evaluate the relationship between thiol-disulfide homoeostasis and hemogram parameters in COVID-19 patients.
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Key Findings & Data:Methods: Total thiol(TT), Native thiol(NT), dynamic disulfide status(DDS), DDS/NT, DDS/TT, NT/TT ratio and CBC parameters were analyzed in 68 patients with positive COVID-19 and 31 healthy individuals.
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Conclusion & Impact:TT, NT, DD and lymphocyte levels of COVID-19 patients treated in medical floor were higher than those treated in intensive care unit; WBC, neutrophil and NLR were low(P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:COVID-19 · toplam tiyol · doğal tiyol

Abstract

Objective: In this study, we aimed to evaluate the relationship between thiol-disulfide homoeostasis and hemogram parameters in COVID-19 patients. Methods: Total thiol(TT), Native thiol(NT), dynamic disulfide status(DDS), DDS/NT, DDS/TT, NT/TT ratio and CBC parameters were analyzed in 68 patients with positive COVID-19 and 31 healthy individuals. Results: TT, NT, DD, hemoglobin and hematocrit levels were higher in the control group than in patient groups. TT, NT, DD and lymphocyte levels of COVID-19 patients treated in medical floor were higher than those treated in intensive care unit; WBC, neutrophil and NLR were low(P

Özet

Amaç: Bu çalışmada, COVID-19 hastalarında tiyol-disülfid homoeostazı ile hemogram parametreleri arasındaki ilişkiyi değerlendirmeyi amaçladık. Gereç Yöntem: Total tiyol (TT), Native tiyol (NT), dinamik disülfid durumu (DDS), DDS / NT, DDS / TT, NT / TT oranı ve CBC parametreleri COVID-19 pozitif 68 hasta ve 31 sağlıklı bireyde analiz edildi. Bulgular: Kontrol grubunda TT, NT, DD, hemoglobin ve hematokrit düzeyleri hasta gruplarına göre daha yüksekti. Serviste tedavi gören COVID-19 hastalarının TT, NT, DD ve lenfosit seviyeleri yoğun bakım ünitesinde tedavi edilenlere göre daha yüksekti; WBC, nötrofil ve NLO düşüktü (P

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Cite This Article

ŞEKEROĞLU, M. R., ÇOKLUK, E., YAYLACI, S., ERDEM, A. F., TUNCER, F. B., DHEİR, H., GÜÇLÜ, E., ÖĞÜTLÜ, A., ÇEKİÇ, D., AYDIN, A., CİNEMRE, F. B. S. (2021). Thiol-Disulphide Homoeostasis in COVID-19: Evaluation of its Relationship with Complete Blood Count Parameters. KONURALP TIP DERGİSİ, Cilt: 13 - Sayı: S1, 460–467. https://ajindex.com/articles/686671

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