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Journals / KONURALP TIP DERGİSİ / 2026 / Volume: 18 Issue: 2

Pleomorphic Lipoma of the Left Buccal Mucosa: Report of a Case with an Emphasis on its Differential Diagnoses

Manas Bajpai(Rural Dental College, Department of Oral Pathology and Microbiology)0000-0001-6168-3069
Shubhangi Mani(Rural Dental College, Department of Oral Pathology and Microbiology)0009-0008-4160-6857
Saurabh L Sabnis(Rural Dental College, Department of Oral Pathology and Microbiology)0000-0001-7646-3499
Pages
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Publication Date
2026-06-26
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case highlights the rare occurrence of pleomorphic lipoma in the buccal mucosa, emphasizing the importance of thorough histopathological evaluation for accurate diagnosis and differentiation from malignant lesions.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Lipomas are common benign mesenchymal tumors composed of mature adipocytes, typically found in subcutaneous tissues.
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Key Findings & Data:Its clinical significance lies in its potential to mimic a well-differentiated liposarcoma, necessitating accurate histopathological diagnosis.
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Conclusion & Impact:This case highlights the rare occurrence of pleomorphic lipoma in the buccal mucosa, emphasizing the importance of thorough histopathological evaluation for accurate diagnosis and differentiation from malignant lesions.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Pleomorphic lipoma · buccal mucosa · oral cavity

Abstract

Lipomas are common benign mesenchymal tumors composed of mature adipocytes, typically found in subcutaneous tissues. While common in the head and neck region, their occurrence in the oral cavity, especially variants like pleomorphic lipoma, is exceedingly rare. Pleomorphic lipoma (PL) is a distinct histological subtype characterized by a mixture of mature adipocytes, spindle cells, rope-like collagen bundles, and classic "floret-like" multinucleated giant cells. Its clinical significance lies in its potential to mimic a well-differentiated liposarcoma, necessitating accurate histopathological diagnosis. We report a case of pleomorphic lipoma in a 33-year-old male who presented with a slowly growing, painless mass in his left buccal mucosa. This case highlights the rare occurrence of pleomorphic lipoma in the buccal mucosa, emphasizing the importance of thorough histopathological evaluation for accurate diagnosis and differentiation from malignant lesions.

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Cite This Article

Bajpai, M., Mani, S., Sabnis, S. L. (2026). Pleomorphic Lipoma of the Left Buccal Mucosa: Report of a Case with an Emphasis on its Differential Diagnoses. KONURALP TIP DERGİSİ, Volume: 18 Issue: 2. https://doi.org/10.18521/ktd.1798809

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