Journals / Journal of advances in vetbio science and techniques / 2018 / Cilt: 3 - Sayı: 2

May clinoptilolite be an alternative and natural solution for the treatment of giardiasis in lambs?

Klinoptilolit kuzularda giardiazis sağaltımına yönelik alternatif ve doğal bir çözüm olabilir mi?

Pages
16–20
Publication Date
2018-08-31
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therapeutic efficacy of clinoptilolite wasdetermined by microscopical examination of faecal samples collected rectally on days 0 and 10.Results: Comparison of control and treatment intragroups revealed 97,2% reduction (p 0˂0,05)for cyst excretion in clinoptilolite treated group.Conclusion: In conclusion, it may be safey suggested that oral clinoptilolite administration for10 days effectively reduct cyst excretion with antiparasitic efficacy among lambs with giardiasis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective The aim of this field study was to detect the therapeutic efficacy of oral clinoptilolitein lambs with giardiasis.Methods: A total of fourteen lambs naturally infected with G. duodenalis at the age of 23 to 56days, of both sexes were enrolled into the study from a lamb farm located in Aydin province.Diagnosis was based on rapid diagnositc test kits with ELISA principle.
📊
Key Findings & Data:Lambs with giardiasiswere randomly assigned into two groups (n=7), group I [1 g/kg clinoptilolite for 10 days or groupII [were left as control without receiving any drug].
💡
Conclusion & Impact:Therapeutic efficacy of clinoptilolite wasdetermined by microscopical examination of faecal samples collected rectally on days 0 and 10.Results: Comparison of control and treatment intragroups revealed 97,2% reduction (p 0˂0,05)for cyst excretion in clinoptilolite treated group.Conclusion: In conclusion, it may be safey suggested that oral clinoptilolite administration for10 days effectively reduct cyst excretion with antiparasitic efficacy among lambs with giardiasis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kuzu · giardiazis · klinoptilolit

Abstract

Objective The aim of this field study was to detect the therapeutic efficacy of oral clinoptilolitein lambs with giardiasis.Methods: A total of fourteen lambs naturally infected with G. duodenalis at the age of 23 to 56days, of both sexes were enrolled into the study from a lamb farm located in Aydin province.Diagnosis was based on rapid diagnositc test kits with ELISA principle. Lambs with giardiasiswere randomly assigned into two groups (n=7), group I [1 g/kg clinoptilolite for 10 days or groupII [were left as control without receiving any drug]. Therapeutic efficacy of clinoptilolite wasdetermined by microscopical examination of faecal samples collected rectally on days 0 and 10.Results: Comparison of control and treatment intragroups revealed 97,2% reduction (p 0˂0,05)for cyst excretion in clinoptilolite treated group.Conclusion: In conclusion, it may be safey suggested that oral clinoptilolite administration for10 days effectively reduct cyst excretion with antiparasitic efficacy among lambs with giardiasis.

Özet

Amaç: Bu saha çalışması giardiasisli kuzularda oral yolla uygulanan klinoptilolitin etkinliğininbelirlenmesi amacıyla gerçekleştirildi.Yöntemler: Aydın ili sınırlarında yer alan özel bir işletmede ishal mevcut ve G. duodenalis iledoğal enfekte her iki cinsiyetten ve 23-56 günlük yaştaki 14 kuzu değerlendirildi. Tanı amacıylaELISA prensibi ile çalışan hızlı tanısal test kitleri yapıldı. Giardiazisli kuzular her grupta n=7olarak rastgele I. gruba [1 g/kg dozda 10 gün oral yolla klinoptilolit uygulanırken] ya da II. gruba[ilaç uygulaması yapılmaksızın kontrol grubu] ayırıldı. Klinoptilolitin sağaltım etkinliği 0. ve 10.günlerde rektal yolla elde edilen dışkı örneklerinin mikroskobik muayenesiyle değerlendirildi.Bulgular: Kontrol ve sağaltım grupları arasında karşılaştırmalarda 10. günde klinoptilolit ilesağaltılan grupta kist atılımında % 97,2’lik azalma belirgindi (p 0˂0,05).Sonuç: Giardiazisli kuzularda oral yolla 10 gün uygulanan klinoptilolitin kist atılımını etkinşekilde azalttığı ve antiparaziter etkinlik sağladığı görüldü.

🔖

Cite This Article

AYAN, A., URAL, D. A., PAŞA, S., ERDOĞAN, S., ERDOĞAN, H. (2018). May clinoptilolite be an alternative and natural solution for the treatment of giardiasis in lambs?. Journal of advances in vetbio science and techniques, Cilt: 3 - Sayı: 2, 16–20. https://ajindex.com/articles/676923

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (2)

  1. Alıç Ural, D., Aysul, N., Gultekin, M. (2016). The Efficacy of Oral Administration of Clinoptilolite Against Naturally Occuring Giardiasis in Calves. Kocatepe Vet J, 9(4), 288-293. DOI: 10.5578/kvj.28122Alıç Ural, D., Erdoğan, H., Toplu, S., Ayan, A. (2017). Oğlaklarda Giardiazis Kontrolüne Yönelik Oral Klinoptilolit Uygulaması. Kocatepe Vet J, 10(3), 158-163. DOI:10.5578/kvj.57512Aloisio, F., Filippini, G., Antenucci, P., Lepri, E., Pezzotti, G., Cacciò, SM. (2006). Severe weight loss in lambs infected with Giardia duodenalis assemblage B. Vet Parasitol, 142(1-2), 154-158. DOI:10.1016/j.vetpar.2006.06.023Ayan, A., Ural, K., Aysul, N., Gültekin, M., Erdoğan, H., Balıkçı, C., Toplu, S., Toros, G. (2016). Natural Cyst Shedding in Calves Infected with Giardia duodenalis. JAVST, 1(1), 14-19.Caccio, S.M. (2015). Giardiasis: a zoonotic infection or not? In: Sing A (ed’s), Zoonoses-ınfections affecting humans and animals. New-York (NY), Springer, 821-848.Cacció, S.M., de Giacomo, M., Pozio, E. (2002). Sequence analysis of the β giardin gene and development of a PCR-RFLP assay to genotype Giardia duodenalis cysts from human faecal samples. Int J Parasitol, 32(8), 1023-1030. DOI:10.1016/S0020-7519(02)00068-1Ey, PL., Mansouri, M., Kulda, J., Nohynkova, E., Monis, P.T., Andrews, R.H., Mayrhofer, G. (1997). Genetic analysis of Giardia from hoofed farm animals reveals artiodactyls-specific and potentially zoonotic genotypes. J Eukaryot Microbiol, 44(6), 625-635.
  2. Geurden, T., Thomas, P., Casaert, S., Vercruysse, J., Claerebout, E. (2008). Prevalence and molecular characterization of Cryptosporidium and Giardia in lambs and goat kids in Belgium. Vet Parasitol, 155(1-2), 142-145. DOI:10.1016/j.vetpar.2008.05.002Geurden, T., Vercruysse, J., Claerebout, E. (2010). Is Giardia a signifcant pathogen in production animals? Exp Parasitol, 124(1), 98-106. DOI:10.1016/j.exppara.2009.03.001 Geurden, T., Pohleb, H., Sarrea, C., Dreesena, L., Vercruyssea, J., Claerebouta, E. (2011). The effcacy of a treatment with fenbendazole against an experimental Giardia duodenalis infection in lambs. Small Rum Res, 96(2-3), 211-215. DOI:10.1016/j.smallrumres.2010.12.004Giangaspero, A., Paoletti, B., Iorio, R., Traversa, D. (2005). Prevalence and molecular characterization of Giardia duodenalis from sheep in central Italy. J Parasitol Res, 96(1), 32-37. DOI:10.1007/s00436-005-1317-7Gultekin, M., Ural, K., Aysul, N., Ayan, A., Balikci, C., Akyildiz, G. (2016). The efficacy of chloroquine treatment