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Journals / Journal of advances in vetbio science and techniques / 2018 / Cilt: 3 - Sayı: 3

The Effectiveness of Echinocandin Group Antimycotics in the Treatment of Systemic Aspegillosis and Candidiasis, and Its Role in Veterinary Medicine

Sistemik Aspergillosis ve Kandidiyazisin Tedavisinde Ekinokandin Grubu Antimikotiklerin Etkinliği ve Veteriner Hekimliğindeki Yeri

Belgi NASİBOĞLU
Banu DOKUZEYLÜL
Fatma ALKAN
Ümit BARUTÇU
Mehmet OR
Pages
84–89
Publication Date
2018-12-31
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, it is aimed to increase the echinocandin use and their awareness in veterinary medicine.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Fungal diseases are major problems of human and animal health.
📊
Key Findings & Data:For this reason, many antifungals have been produced over the last forty years and they have started to use in the health field.
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Conclusion & Impact:In this review, it is aimed to increase the echinocandin use and their awareness in veterinary medicine.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:antifungal · ekinokandin · veteriner hekimliği

Abstract

Fungal diseases are major problems of human and animal health. For this reason, many antifungals have been produced over the last forty years and they have started to use in the health field. Usage of antifungal drugs induce resistant fungal agents that’s why these condition necessitates alternative drugs. In this review, it is aimed to increase the echinocandin use and their awareness in veterinary medicine.

Özet

İnsan ve hayvan sağlığı açısından fungal hastalıklar büyük sorun yaratmaktadır. Bu nedenle son kırk yılda pek çok antifungal üretilmiş ve sağlık alanında kullanıma başlanmıştır. İlaçların kullanımı ile birlikte dirençli mantar etkenlerinin ortaya çıkması sık kullanılan antimikotiklerin yerine alternatif ilaçların üretilmesini zorunlu kılmıştır. Bu derlemede, sistemik mikozlardan Candida spp. ve Aspergillus spp. tedavisinde uzun süredir kullanılan, polien ve azol grubu antifungallere alternatif olarak; veteriner hekimlikte ekinokandin grubu ilaçların kullanımının arttırılması yönünde bilinç uyandırmak amaçlanmıştır.

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Cite This Article

NASİBOĞLU, B., DOKUZEYLÜL, B., ALKAN, F., BARUTÇU, Ü., OR, M. (2018). The Effectiveness of Echinocandin Group Antimycotics in the Treatment of Systemic Aspegillosis and Candidiasis, and Its Role in Veterinary Medicine. Journal of advances in vetbio science and techniques, Cilt: 3 - Sayı: 3, 84–89. https://ajindex.com/articles/676919

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References (10)

  1. Bachmann, S. P., VandeWalle, K., Ramage, G., Patterson, T. F., Wickes, B. L., Graybill, J. R., & Lopez-Ribot, J. L. (2002). In vitro activity of caspofungin against Candida albicans biofilms. Antimicrob Agents Chemother 46 (11):3591-3596.
  2. Balashov, S. V., Park, S. & Perlin, D. S. (2006). Assessing resistance to th echinocandin antifungal drug caspofungin in Candida albicans by profiling mutations in FKS1. Antimicrob Agents Chemother 50 (6):2058-2063.
  3. Barrs, V. R., Halliday, C., Martin, P., Wilson, B., Krockenberger, M., Gunew, M.,. & Hocking, A. (2012). Sinonasal and sino-orbital aspergillosis in 23 cats: aetiology, clinicopathological features and treatment outcomes. The Veterinary Journal, 191(1), 58-64.
  4. Barrs, V. R., van Doorn, T. M., Houbraken, J., Kidd, S. E., Martin, P., Pinheiro, M. D.,. & Samson, R. A. (2013). Aspergillus felis sp. nov., an emerging agent of invasive aspergillosis in humans, cats, and dogs. PLoS One, 8(6), e64871. Barrs, V. R., Ujvari, B., Dhand, N. K., Peters, I. R., Talbot, J., Johnson, L. R.,. & Belov, K. (2015). Detection of Aspergillus-specific antibodies by agar gel double immunodiffusion and IgG ELISA in feline upper respiratory tract aspergillosis. The Veterinary Journal, 203(3), 285-289.
  5. Bowman, J. C., Hicks, P. S., Kurtz, M. B., Rosen, H., Schmatz, D. M., Liberator, P. A., & Douglas, C. M. (2002). The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro. Antimicrobial agents and chemotherapy, 46(9), 3001-3012.
  6. Bowman, J. C., Abruzzo, G. K., Flattery, A. M., Gill, C. J., Hickey, E. J., Hsu, M. J.,. & Wang, T. C. (2006). Efficacy of caspofungin against Aspergillus flavus, Aspergillus terreus, and Aspergillus nidulans. Antimicrobial agents and chemotherapy, 50(12), 4202-4205.
  7. Brown, G. D., Denning, D. W., Gow, N. A., Levitz, S. M., Netea, M. G., & White, T. C. (2012). Hidden killers: human fungal infections. Science translational medicine, 4(165), 165rv13-165rv13. Calvo, E., Pastor, F. J., Salas, V., Mayayo, E., & Guarro, J. (2012). Combined therapy of voriconazole and anidulafungin in murine infections by Aspergillus flavus. Mycopathologia, 173(4), 251-257.
  8. Chandrasekar, P. H., & Sobel, J. D. (2006). Micafungin: a new echinocandin. Clinical infectious diseases, 42(8), 1171-1178.
  9. Chen, S. C. A., Slavin, M. A., & Sorrell, T. C. (2011). Echinocandin antifungal drugs in fungal infections. Drugs, 71(1), 11-41.
  10. Cleveland, A. A., Farley, M. M., Harrison, L. H., Stein, B., Ho