Journals / Ulusal Romatoloji Dergisi / 2022 / Cilt: 14 - Sayı: 2

Sleep quality and its association with disease activity, depression and quality of life in Behçet’s disease patients

Behçet hastalarında uyku kalitesinin hastalık aktivitesi, depresyon ve hayat kalitesi ile ilişkisinin değerlendirilmesi

Pages
81–86
Publication Date
2022-11-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The disease activity was not associated with sleep quality but correlated with fatigue, depression, anxiety, QoL scales (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Quality of sleep is one of the main predictors of quality of life (QoL).
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Key Findings & Data:Methods: A cross-sectional study of 105 BD and 85 healthy controls was conducted.
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Conclusion & Impact:The disease activity was not associated with sleep quality but correlated with fatigue, depression, anxiety, QoL scales (p
🔬Design:Survey & Empirical Study
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Quality of sleep is one of the main predictors of quality of life (QoL). Data on sleep quality and associated factors are limited in Behçet’s disease (BD), a systemic inflammatory disorder with different organ manifestations. In this study, we assesed depression, anxiety and sleep disorders and their associations with disease activity of Turkish patients with BD to establish the relationship between sleep quality, BD activity and QoL scales. Methods: A cross-sectional study of 105 BD and 85 healthy controls was conducted. All subjects completed short form (SF-36), health assessment questionnaire, hospital anxiety and depression scale, multidimensional assessment of fatigue scale (MAF), American College of Rheumatology 2010 fibromyalgia criteria and sleep quality assessed with the Pittsburgh sleep quality index (PSQI). Behçet’s syndrome activity score was used to determine the disease activity of BD. Results: PSQI scores of patients with BD were significantly higher compared to the control group (p=0.001). Among patients BD patients, groups with poor or good sleep quality had similar patient characteristics in terms of gender, education level, smoking, depression level, major organ involvement and presence of fibromyalgia. Among the clinical features, only genital ulcers were associated with poor sleep quality (p=0.036). After regression analysis, mean PSQI score of patients with BD was associated with age, mental component score of SF-36 and MAF score. The disease activity was not associated with sleep quality but correlated with fatigue, depression, anxiety, QoL scales (p

Özet

Amaç: Uyku kalitesi, hayat kalitesinin en önemli belirleyicilerinden biridir. Farklı organ tutulumları ile seyreden sistemik enflamatuvar bir hastalık olan Behçet hastalığında hastaların uyku kalitesi ve bunu etkileyen faktörlerle ilgili yayınlanmış çalışmalar sınırlıdır. Bu çalışmada Behçet hastalarında depresyon, anksiyete ve uyku bozukluklarının belirlenmesi ve uyku kalitesi ile hastalık aktivitesi ve yaşam kalite indeksleri arasındaki ilişkisinin değerlendirilmesi amaçlanmıştır. Yöntem: Kesitsel çalışmamızda 105 Behçet hastası ve 85 sağlıklı kontrol değerlendirilmiştir. Tüm katılımcılara kısa form (KF-36), sağlık değerlendirme anketi, hastane anksiyete ve depresyon anketi, yorgunluk çok boyutlu değerlendirme anketi, Amerikan Romatoloji Derneği 2010 fibromiyalji kriterleri, uyku kalitesi değerlendirilmesi için Pittsburg uyku kalite indeksi (PUKI), hastalık aktivite değerlendirilmesi için Behçet sendrom aktivite skoru uygulandı. Bulgular: Behçet hastalarının PUKI skorları sağlıklı kontrole göre anlamlı olarak daha yüksekti (p=0,001). İyi ve kötü uyku kalitesine sahip Behçet hastaları değerlendirildiğinde cinsiyet, eğitim düzeyi, sigara içiciliği, depresyon seviyesi, fibromiyalji ve majör organ tutulumu benzerdir. Klinik özellikler arasında ise sadece aktif genital ülserin varlığı kötü uyku kalitesi ile ilişkili bulunmuştur (p=0,036). Regresyon analizinde Behçet hastalarının ortalama PUKI skoru yaşla, KF-36’nın mental bileşen özeti ve yorgunlukla ilişkili bulunmuştur. Hastalık aktivitesinin uyku kalitesi ile ilişkisi bulunmamakla birlikte yorgunluk, depresyon ve anksiyete ve yaşam kalite ölçütleri ile korelasyonu saptanmıştır (p

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Cite This Article

KORKMAZ, Ö. P., AKSOY, A., İLHAN, B., ÖNER, F. A., DİRESKENELİ, H. (2022). Sleep quality and its association with disease activity, depression and quality of life in Behçet’s disease patients. Ulusal Romatoloji Dergisi, Cilt: 14 - Sayı: 2, 81–86. https://ajindex.com/articles/655401

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References (15)

  1. Sakane T, Takeno M, Suzuki N, Inaba G. Behcet’s disease. N Engl J Med 1999;341:1284-91
  2. Ohno S, Ohguchi M, Hirose S, Matsuda H, Wakisaka A, Aizawa M. Close Association of HLA-Bw51 With Behçet’s Disease. Arch Ophthalmol 1982;100:1455-58
  3. Stojanovich L. Stress and autoimmunity. Autoimmun Rev 2010;9:A271-6
  4. Kaneko F, Togachi A, Nomura E, et al. Role of Heat Shock Protein Derived from Streptococcus sanguinis in Behcet?s Disease. J Medical Microbiol Diagnosis 2012;03
  5. Masoumi M, Tabaraii R, Shakiba S, Shakeri M, Smiley A. Association of lifestyle elements with self-rated wellness and health status in patients with Behcet’s disease. BMC Rheumatol 2020;4:49
  6. Tascilar NF, Tekin NS, Ankarali H, et al. Sleep disorders in Behcet’s disease, and their relationship with fatigue and quality of life. J Sleep Res 2012;21:281-8
  7. Taner E, Coşar B, Burhanoğlu S, Calikoğlu E, Onder M, Arikan Z. Depression and anxiety in patients with Behçet’s disease compared with that in patients with psoriasis. Int J Dermatol 2007;46:1118-24
  8. Lee J, Kim SS, Jeong HJ, et al. Association of sleep quality in Behcet disease with disease activity, depression, and quality of life in Korean population. Korean J Intern Med 2017;32:352-9
  9. Criteria for diagnosis of Behçet’s disease. International Study Group for Behçet’s Disease. Lancet 19905;335:1078-80
  10. Yilmaz S, Simsek I, Cinar M, et al. Patient-driven assessment of disease activity in Behçet’s syndrome: cross-cultural adaptation, reliability and validity of the Turkish version of the Behçet’s Syndrome Activity Score. Clin Exp Rheumatol 2013;31(3 Suppl 77):77-83
  11. Koçyigit H, Aydemir O, Fisek G. Kısa Form-36 (KF-36)’nın Türkçe versiyonunun güvenilirliği ve geçerliliği. İlaç ve Tedavi Dergisi 1999;12:102-6
  12. Küçükdeveci AA, Sahin H, Ataman S, Griffiths B, Tennant A. Issues in cross-cultural validity: example from the adaptation, reliability, and validity testing of a Turkish version of the Stanford Health Assessment Questionnaire. Arthritis Rheum 2004;51:14-9
  13. Ware JE Jr, Kosinski M, Bayliss MS, McHorney CA, Rogers WH, Raczek A. Comparison of methods for the scoring and statistical analysis of SF-36 health profile and summary measures: summary of results from the Medical Outcomes Study. Med Care 1995;33(4 Suppl):AS264-79
  14. Bruce B, Fries JF. The Health Assessment Questionnaire (HAQ). Clin Exp Rheumatol 2005;23(Suppl 39):S14-8
  15. Multidimensional Assessment of Fatigue (MAF) User’s Guide. University of W