Journals / Ulusal Romatoloji Dergisi / 2022 / Cilt: 14 - Sayı: 2

CPPD-related pseudoneuroarthropathy in a patient with myelodysplastic syndrome

Miyelodisplastik sendromlu bir olguda CPPD ilişkili psödonöroartropati

Pages
106–109
Publication Date
2022-11-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we report an interesting CPPD case presenting as pseudo-CA in a patient with myelodysplastic syndrome.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The calcium pyrophosphate deposition (CPPD) disease is a common form of crystal arthropathy.
📊
Key Findings & Data:It usually affects elderly patients.
💡
Conclusion & Impact:Here, we report an interesting CPPD case presenting as pseudo-CA in a patient with myelodysplastic syndrome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The calcium pyrophosphate deposition (CPPD) disease is a common form of crystal arthropathy. It usually affects elderly patients. The clinical and radiological features of CPPD vary widely, so CPPD is a great mimicker of other musculoskeletal conditions. Asymptomatic and destructive forms can present at the same time in the same patients. Several diseases have been proposed to be related to CPPD, but hematologic disorders have not been reported to occur concurrently. Charcot arthropathy (CA) is associated with neuropathy and is characterized by erosive joint disease. Here, we report an interesting CPPD case presenting as pseudo-CA in a patient with myelodysplastic syndrome.

Özet

Kalsiyum pirofosfat depozisyon (CPPD) hastalığı kristal artropatilerin yaygın bir formudur. Genellikle yaşlı bireyleri etkiler. CPPD’nin radyolojik ve klinik özellikleri değişken olup bu yüzden kas-iskelet sistemi hastalıklarının iyi bir taklitçisidir. Asemptomatik ve destrüktif formları aynı hastada aynı anda bulunabilir. CPPD ilişkili birçok hastalık tanımlanmış olup hematolojik hastalıklarla ilişkisine dair kanıt yoktur. Charcot artropatisi (CA) nöropatik hastalıklarla ilişkisi olup eklem erozyonları ile karakterizedir. Makalemizde miyelodisplastik sendromlu bir hastada psödo-CA ile prezente olan enteresan bir CPPD olgusunu sunuyoruz.

🔖

Cite This Article

PEKDİKER, M., KİMYON, G. (2022). CPPD-related pseudoneuroarthropathy in a patient with myelodysplastic syndrome. Ulusal Romatoloji Dergisi, Cilt: 14 - Sayı: 2, 106–109. https://ajindex.com/articles/655398

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Dieppe PA, Alexander GJM, Jones HE, et al. Pyrophosphate arthropathy: a clinical and radiological study of 105 cases. Ann Rheum Dis 1982;41:371-6
  2. Neame RL, Carr AJ, Muir K, Doherty M. UK community prevalence of knee chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte. Ann Rheum Dis 2003;62:513-8
  3. Hollander JL, Jessar RA, McCarty DJ. Synovianalysis:an aid in arthritis diagnosis. Bull Rheum Dis 1961;12:263-4
  4. McCarty DJ. Calcium pyrophosphate dihydrate crystal deposition disease-1975. Arthritis Rheum 1976;19 Suppl 3:275-85
  5. Zhang W, Doherty M, Bardin T, et al. European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis 2011;70:563-70
  6. Steinbach LS. Calcium pyrophosphate dihydrate and calcium hydroxyapatite crystal deposition diseases: imaging perspectives. Radiol Clin N Am 2004;42:185-205, vii
  7. Rosenthal AK, Ryan LM. Calcium Pyrophosphate Deposition Disease. N Eng J Med 2016;374:2575-84
  8. Johnson JT. Neuropathic fractures and joint injuries. Pathogenesis and rationale of prevention and treatment. J Bone Joint Surg Am 1967;49:1-30
  9. Menkes CJ, Simon F, Delrieu F, Forest M, Delbarre F. Destructive arthropathy in chondrocalcinosis articularis. Arthritis Rheum 1976;19 Suppl 3:329-48
  10. Resnick D, Niwayama G, Goergen TG, et al. Clinical, radiographic and pathologic abnormalities in calcium pyrophosphate dihydrate deposition disease (CPPD): pseudogout. Radiology 1977;122:1-15
  11. Lomax A, Ferrero A, Cullen N, Goldberg A, Singh D. Destructive pseudo-neuroarthropathy associated with calcium pyrophosphate deposition. Foot Ankle Int 2015;36:383-90
  12. Iqbal SM, Aslam HM, Faizee F, Qadir S, Waheed S. Pseudogout: An Autoimmune Paraneoplastic Manifestation of Myelodysplastic Syndrome. Cureus 2018;10:e3372
  13. Tedeschi SK, Stone RM, Helfgott SM. Calcium Pyrophosphate Crystal Inflammatory Arthritis (Pseudogout) with Myelodysplastic Syndrome: A New Paraneoplastic Syndrome? J Rheumatol 2017;44:1101-2
  14. Zhang W, Doherty M, Pascual E, et al. EULAR recommendations for calcium pyrophosphate deposition. Part II: management. Ann Rheum Dis 2011;70:571-5
  15. Wolach O, Stone R. Autoimmunity and Inflammation in Myelodysplastic Syndromes. Acta Haematol 2016;136:108-17.