Journals / Türk Oftalmoloji Dergisi / 2005 / Cilt: 35 - Sayı: 5

Ocular findings in patients with multiple sclerosis

Multipl skleroz olgularında göz bulguları

Pages
460–466
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Patients with multiple sclerosis should undergo regular ocular examination for early detection of frequently associated ocular manifestations.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate ocular findings of patients with definite multiple sclerosis (MS).
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Key Findings & Data:Those with adequate visual acuity performed 24-2 full threshold standard achromatic perimetry (Humphrey Field Analyzer II).
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Conclusion & Impact:Conclusion: Patients with multiple sclerosis should undergo regular ocular examination for early detection of frequently associated ocular manifestations.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate ocular findings of patients with definite multiple sclerosis (MS). Methods: Consecutive patients with definite MS underwent complete ocular examination. Those with adequate visual acuity performed 24-2 full threshold standard achromatic perimetry (Humphrey Field Analyzer II). Visual evoked potentials (VEP) were obtained. Correlation between VEP latencies and visual fields parameters was investigated. Results: Average age of 42 females (62%) and 26 males (38%) was 31.7 ± 8.9 years (range, 15-56 years). Optic neuritis in 36 cases (53%), vitreous opacity in 18 cases (26%), nystagmus in 7 cases (10%), abducens nerve palsy in 3 cases (4%), sensory exotropia in 3 cases (4%), punctate lenticular opacities in 3 cases (4%) and internuclear ophthalmoplegia in 2 cases (3%) were noted. VEP latencies of 28 eyes with prior optic neuritis (138.9 ± 19.6 msn) were longer than eyes without optic neuritis (117.1 ± 13.2 msn) (p=0.000). Mean defect values of 16 eyes with prior optic neuritis were lower than of 34 eyes without optic neuritis (p=000); number of test points below 5% probability in eyes with prior*optic neuritis was higher than those without (p=0.014). Significant correlation was found between VEP latencies and short fluctuation in the eyes with prior optic neuritis (r=0.703, p=0.023); no correlation was found with the other visual field parameters. Conclusion: Patients with multiple sclerosis should undergo regular ocular examination for early detection of frequently associated ocular manifestations.

Özet

Amaç: Kesin multipl skleroz (MS) olgularında göz bulgularım değerlendirmek.Yöntem: Kesin MS'li ardışık olgulara tam bir göz muayenesi yapıldı. Görme keskinliği yeterli düzeyde olanlara 24-2 tam eşik testi ile standart akromatik perimetri (Humphrey Field Analyzer II) uygulandı. Görsel uyaranlı potansiyel cevapları (VEP) elde edildi. VEP latansları ile görme alanı parametreleri arasında korelasyon araştırıldı. Bulgular: Toplam 42 erkek (%62) ve 26 kadın (%38) olgunun yaş ortalaması 31.7 ± 8.9 yıl (sınırlar, 15-56 yıl) idi. Optik nörit 36 olguda (%53), vitreus opasitesi 18 olguda (%26), nistagmus 7 olguda (%10), abdusens sinir felci 3 olguda (%4), sensorial ekzotropya 3 olguda (%4), punktat lens opasitesi 3 olguda (%4) ve internükleer oftalmopleji 2 olguda (%3) saptandı. Optik nörit geçiren 28 gözün VEP latansları (138.9 ± 19.6 msn) optik nörit geçirmeyen 68 gözün VEP latanslarından (117.1 ± 13.2 msn) uzundu (p=0.000). Optik nörit geçiren 16 gözün ortalama defekt (MD) değeri optik nörit geçirmeyen 34 gözden düşük (p=000); olasılık değerleri %5'in altındaki test nokta sayısı optik nörit geçiren gözlerde geçirmeyenlerden fazla saptandı (p=0.014). Optik nörit geçiren gözlerde VEP latansları ile kısa fluktuasyon (SF) arasında anlamlı korelasyon bulundu (r=0.703, p=0.023); diğer görme alanı parametreleri ile korelasyon bulunmadı. Sonuç: MS olgularında, sıklıkla eşlik eden göz bulgularının erken saptanması için aralıklı olarak göz muayenesi gereklidir.

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Cite This Article

MADEN, A., YURDAKUL, N. Ş., AKIN, B., UĞURLU, K. Ş., YETİMALAR, Y. (2022). Ocular findings in patients with multiple sclerosis. Türk Oftalmoloji Dergisi, Cilt: 35 - Sayı: 5, 460–466. https://ajindex.com/articles/638861

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