Journals / Türk Oftalmoloji Dergisi / 2010 / Cilt: 40 - Sayı: 4

A comparison of optic disc topographic parameters in primary open-angle glaucoma cases with or without family history of glaucoma

Aile hikayesi olan ve olmayan primer açık açılı glokom olgularının optik disk topografilerinin karşılaştırılması

Pages
205–208
Publication Date
2022-11-05
DOI
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Discussion: No differences were detected between the optic disc topographic parameters of the POAG cases with and without family history, whereas it was observed that the POAG cases with positive family history were younger at the time of glaucoma diagnosis.

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Objective & Hypothesis:Purpose: To compare the optic disc topographic parameters of primary open-angle glaucoma (POAG) cases with or without family history of the disease.
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Key Findings & Data:Materia and Method: Cases of POAG, with (26 cases, 52 eyes) or without (28 cases, 56 eyes) family history of glaucoma, were investigated retrospectively.
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Conclusion & Impact:Discussion: No differences were detected between the optic disc topographic parameters of the POAG cases with and without family history, whereas it was observed that the POAG cases with positive family history were younger at the time of glaucoma diagnosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To compare the optic disc topographic parameters of primary open-angle glaucoma (POAG) cases with or without family history of the disease. Materia and Method: Cases of POAG, with (26 cases, 52 eyes) or without (28 cases, 56 eyes) family history of glaucoma, were investigated retrospectively. The following results were recorded: best-corrected visual acuity, slit-lamp, fundus, gonioscopic and perimetric examinations, intraocular pressure (IOP) measured by Goldmann applanation tonometer, analysis of optic disc topography by Heidelberg Retina Tomograph (HRT III), and central corneal thickness (CCT) using ultrasonic pachymeter. Mann-Whitney U, chi-square and t-tests were used for statistical analysis. Results: No statistically significant differences in terms of sex, CCT, IOP, and HRT III parameters were observed between the patients with or without family history of glaucoma. The mean age at the time of glaucoma diagnosis was 48.1±8.6 in the subjects with family history of glaucoma and, 56.4±10.9 in those without family history of the disease. The cases with family history were significantly younger at the time of glaucoma diagnosis than those without family history (p: 0.003). Discussion: No differences were detected between the optic disc topographic parameters of the POAG cases with and without family history, whereas it was observed that the POAG cases with positive family history were younger at the time of glaucoma diagnosis.

Özet

Amaç: Aile hikayesi olan ve olmayan primer açık açılı glokom (PAAG) olgularının tanı esnasındaki optik disk topografik değerlerinin kıyaslanması. Gereç ve Yöntem: Aile hikayesi olan (26 hasta, 52 göz) ve olmayan (28 hasta, 56 göz) PAAG olguları, geriye dönük olarak incelendi. Tüm hastaların düzeltilmiş görme keskinliği, biyomikroskopik, fundus ve gonyoskopik muayeneleri, Goldmann aplanasyon tonometresi ile göziçi basıncı (GİB) değerleri, Heidelberg Retinal Tomografi (HRT) III ile optik disk topografi analizleri, Humphrey otomatize perimetri ile görme alanı incelemeleri ve ultrasonik pakimetri ile merkezi kornea kalınlık (MKK) değerleri kaydedildi. İstatistiksel yöntem olarak Mann-Whitney U testi, ki kare ve t test kullanıldı.Sonuçlar: Ailesinde glokom hikayesi pozitif olan grup ile olmayan grup arasında; yaş, cinsiyet, MKK, GİB, HRT III parametreleri açısından fark saptanmadı. Tanı esnasındaki yaş ortalaması aile hikayesi pozitif olan grupta 48,1±8,6, olmayan grupta ise 56,4±10,9 idi. Aile hikayesi olan olgularda yaş anlamlı olarak daha genç bulundu (p:0,003).Tartışma: Aile hikayesi olan ve olmayan PAAG hastalarında tanı esnasında optik disk topografik parametreleri arasında fark tesbit edilmemiştir. Ancak aile hikayesi olan PAAG olgularında daha erken yaşta tanı konulduğu gözlenmiştir.

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Cite This Article

ELGİN, U., ÖZAL, H., MALKOÇ, E. Ş., ÖNCÜL, H., KARA, C., ÖZTÜRK, F. (2022). A comparison of optic disc topographic parameters in primary open-angle glaucoma cases with or without family history of glaucoma. Türk Oftalmoloji Dergisi, Cilt: 40 - Sayı: 4, 205–208. https://ajindex.com/articles/638444

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References (13)

  1. Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol. 1996;80:389-93
  2. Wolfs RC, Borger PH, Ramrattan RS, et al. Changing views on open-angle glaucoma: definitions and prevalences The Rotterdam Study. Invest Ophthalmol Vis Sci. 2000;41:3309-21
  3. Sheldrick JH, Ng C, Austin DJ, Rosenthal AR. An analysis of referral routes and diagnostic accuracy in cases of suspected glaucoma. Ophthalmic Epidemiol. 1994;1:31-9
  4. Polo V, Larrosa JM, Pablo LE, Pinilla I, Honrubia FM. Correlation of functional and structural measurements in eyes suspected of having glaucoma. J Glaucoma. 1999;8:172-6
  5. Chauhan BC, McCormick TA, Nicolela MT, LeBlanc RP. Optic disc and visual field changes in a prospective longitudinal study of patients with glaucoma: comparison of scanning laser tomography with conventional perimetry and optic disc photography. Arch Ophthalmol. 2001;119:1492-9
  6. Gordon MO, Beiser JA, Brandt JD, et al. The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120:714-20
  7. Azuara-Blanco A, Katz LJ, Spaeth GL, Vernon SA, Spencer F, Lanzl IM. Clinical agreement among glaucoma experts in the detection of glaucomatous changes of the optic disc using simultaneous stereoscopic photographs. Am J Ophthalmol. 2003;136:949-50
  8. Mikelberg FS, Wijsman K, M. S. Reproducibility of topographic parameters obtained with the Heidelberg retina tomograph. J Glaucoma. 1993;2:101-103
  9. Rohrschneider K, Burk RO, Kruse FE, Volcker HE. Reproducibility of the optic nerve head topography with a new laser tomographic scanning device. Ophthalmology. 1994;101:1044-9
  10. Durukan AH, Yucel I, Akar Y, Bayraktar MZ. Assessment of optic nerve head topographic parameters with a confocal scanning laser ophthalmoscope. Clin Exp Ophthalmol. 2004;32:259-64
  11. Zangwill LM, Weinreb RN, Beiser JA, et al. Baseline topographic optic disc measurements are associated with the development of primary open-angle glaucoma: the Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment Study. Arch Ophthalmol. 2005;123:1188-97
  12. Wensor MD, McCarty CA, Stanislavsky YL, Livingston PM, Taylor HR. The prevalence of glaucoma in the Melbourne Visual Impairment Project. Ophthalmology. 1998;105:733-9
  13. Weih LM, Nanjan M, McCarty CA, Taylor HR. Prevalence and predictors of open-angle glaucoma: results from the visual impairment project. Ophthalmology. 2001;108:1966-72. 14.