SavedAdd your journal

Journals / Türk Oftalmoloji Dergisi / 2016 / Cilt: 46 - Sayı: 2

Retinal Nerve Fiber Layer Thicknesses in Three Different Optic Nerve Head Size Groups Measured by Cirrus Spectral Domain Optical Coherence Tomography

Cirrus Spektral Domain Optik Koherens Tomografi ile Ölçülen Optik Sinir Başı Büyüklüklerine göre Üç Farklı Grupta Retina Sinir Lifi Tabakası Kalınlıkları

Sirel GÜR GÜNGÖR
Meriç ÇOLAK
Ali KÜÇÜKÖDÜK
Ahmet AKMAN
Pages
58–61
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This correlation and difference may be the result of a varying distance between the circular scan and the ONH margin

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: To compare the retinal nerve fiber layer (RNFL) thicknesses in three different optic nerve head (ONH) size groups measured by Cirrus spectral domain optical coherence tomography (OCT).Materials and Methods: Between January and March 2013, 253 eyes of 253 healthy subjects were enrolled in this study (mean age: 42.7±7.4 years [28-62 years]; 121 men and 132 women).
📊
Key Findings & Data:The patients were divided into 3 groups according to ONH size: 77 patients in the "small ONH" group (ONH area 1.97 mm2).Results: There were significant differences in superior (p=0.008), inferior (p=0.004) and average RNFL thickness (p=0.001) between the small, medium and large ONH groups.
💡
Conclusion & Impact:This correlation and difference may be the result of a varying distance between the circular scan and the ONH margin
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: To compare the retinal nerve fiber layer (RNFL) thicknesses in three different optic nerve head (ONH) size groups measured by Cirrus spectral domain optical coherence tomography (OCT).Materials and Methods: Between January and March 2013, 253 eyes of 253 healthy subjects were enrolled in this study (mean age: 42.7±7.4 years [28-62 years]; 121 men and 132 women). The patients were divided into 3 groups according to ONH size: 77 patients in the "small ONH" group (ONH area 1.97 mm2).Results: There were significant differences in superior (p=0.008), inferior (p=0.004) and average RNFL thickness (p=0.001) between the small, medium and large ONH groups. Positive correlations between ONH size and inferior/average RNFL thicknesses were significant but very weak (r=0.150, p=0.017 and r=0.157, p=0.013 respectively). Conclusion: RNFL thickness as measured by Cirrus OCT is positively correlated with ONH size and the differences in RNFL thickness were statistically significant between groups. This correlation and difference may be the result of a varying distance between the circular scan and the ONH margin

Özet

Amaç: Cirrus spektral domain optik koherens tomografi (OKT) ile ölçülen optik sinir başı (OSB) büyüklüklerine göre belirlenmiş üç farklı grupta retina sinir lifi tabakası (RSLT) kalınlıklarını karşılaştırmaktır.Gereç ve Yöntem: Ocak-Mart 2013 tarihleri arasında, 253 sağlıklı olgunun 253 gözü çalışmaya alındı (ortalama yaş: 42,7±7,4 yıl [28-62 yıl]; 121 erkek ve 132 kadın). Olgular OSB ölçümüne göre 3 gruba ayrıldı. Yetmiş yedi hasta 'küçük OSB' grubunda (OSB 1,63 mm2'den küçük), 90 olgu 'orta OSB' grubunda (OSB 1,63 mm2 ve 1,97 mm2 arasında) ve 86 olgu 'büyük OSB' grubundaydı (OSB 1,97 mm2'den büyük).Bulgular: Küçük, orta ve büyük OSB gruplarında üst (p=0,008), alt (p=0,004) ve ortalama RSLT kalınlığı (p=0,001) istatistiksel yönden farklıydı. OSB büyüklüğü ile alt ve ortalama RSLT kalınlığı arasında düşük dereceli pozitif korelasyon tespit edildi (sırasıyla; r=0,150, p=0,017 ve r=0,157, p=0,013). Sonuç: Cirrus OKT ile ölçülen RSLT kalınlığı ile OSB büyüklüğü arasında pozitif korelasyon vardır ve gruplar arasında RSLT kalınlığı farklıdır. Bu korelasyon ve farklılığın nedeni dairesel halka ile OSB kenarı arasındaki değişken mesafe olabilir

🔖

Cite This Article

GÜNGÖR, S. G., ÇOLAK, M., KÜÇÜKÖDÜK, A., AKMAN, A. (2022). Retinal Nerve Fiber Layer Thicknesses in Three Different Optic Nerve Head Size Groups Measured by Cirrus Spectral Domain Optical Coherence Tomography. Türk Oftalmoloji Dergisi, Cilt: 46 - Sayı: 2, 58–61. https://ajindex.com/articles/637920

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Herrmann J, Funk J. Diagnostic value of nerve fibre layer photography in glaucoma. Ophthalmologe. 2005;102:778-782.
  2. Alencar LM, Zangwill LM, Weinreb RN, Bowd C, Vizzeri G, Sample PA, Susanna R Jr, Medeiros FA. Agreement for detecting glaucoma progression with the GDx guided progression analysis, automated perimetry, and optic disc photography. Ophthalmology. 2010;117:462-470.
  3. Leung CK, Cheung CY, Weinreb RN, Qiu Q, Liu S, Li H, Xu G, Fan N, Huang L, Pang CP, Lam DS. Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: a variability and diagnostic performance study. Ophthalmology. 2009;116:1257-1263.
  4. Sung KR, Kim DY, Park SB, Kook MS. Comparison of retinal nerve fiber layer thickness measured by Cirrus HD and stratus optical coherence tomography. Ophthalmology. 2009;116:1264-1270.
  5. Mikelberg FS, Yidegiligne HM, White VA, Schulzer M. Relation between optic nerve axon number and axon diameter to scleral canal area. Ophthalmology. 1991;98:60-63.
  6. Funaki S, Shirakashi M, Abe H. Relation between size of optic disc and thickness of retinal nerve fibre layer in normal subject. Br J Ophthalmol. 1998;82:1242-1245.
  7. Mikelberg FS, Yidegiligne HM, White VA, Schulzer M. Relation between optic nerve axon number and axon diameter to scleral canal area. Ophthalmol. 1991;98:60-63.
  8. Savini G, Zanini M, Carelli V, Sadun AA, Ross-Cisneros FN, Barboni P. Correlation between retinal nerve fibre layer thickness and optic nerve head size: an optical coherence tomography study. Br J Ophthalmol. 2005;89:489-492.
  9. Savini G, Barboni P, Carbonelli M, Zanini M. The effect of scan diameter on retinal nerve fiber layer thickness measurement using stratus optic coherence tomography. Arch Ophthalmol. 2007;125:901-905.
  10. Kaushik S, Pandav SS, Ichhpujani P, Gupta A. Fixed-diameter scan protocol preferable for retinal nerve fibre layer measurement by optic coherence tomography in all sizes of optic discs. Br J Ophthalmol. 2009;93:895-900.
  11. Schuman JS, Pedut-Kloizman T, Hertzmark E, Hee MR, Wilkins JR, Coker JG, Puliafito CA, Fujimoto JG, Swanson EA. Reproducibility of nerve fiber layer thickness measurements using optical coherence tomography. Ophthalmology. 1996;103:1889-1898.
  12. Jonas JB, Budde WM, Panda-Jonas S. Ophthalmoscopic evaluation of the parapapillary region of the optic nerve head. Klin Oczna. 2004;106(Suppl 1-2):279-289.
  13. Mansoori T, Viswanath K, Balakrishna N. Correlation between peripapillary retinal nerve fiber layer thickness and optic nerve head parameters