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Journals / Türk Oftalmoloji Dergisi / 2020 / Cilt: 50 - Sayı: 6

Impact of Platelet Count in Retinopathy of Prematurity

Prematüre Retinopatisi Gelişiminde Trombosit SayısınınEtkisi

Nedime ŞAHİNOĞLU KEŞKEK
Hande GÜLCAN
Gürsel YILMAZ
İmren AKKOYUN
Pages
351–355
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Lower platelet count in the first week after birth is a risk factor for ROP development in addition to the previouslyestablished factors of ventilation need, low BW, and low GA.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The aim of the study was to investigate the risk factors for retinopathy of prematurity (ROP), including platelet count.
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Key Findings & Data:Materials and Methods: This retrospective study analyzed 137 infants in 3 subgroups: no ROP; mild ROP, and severe ROP requiringlaser treatment (type 1 ROP).
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Conclusion & Impact:Conclusion: Lower platelet count in the first week after birth is a risk factor for ROP development in addition to the previouslyestablished factors of ventilation need, low BW, and low GA.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: The aim of the study was to investigate the risk factors for retinopathy of prematurity (ROP), including platelet count. Materials and Methods: This retrospective study analyzed 137 infants in 3 subgroups: no ROP; mild ROP, and severe ROP requiringlaser treatment (type 1 ROP). A retrospective review of records was performed and statistical analysis of possible risk factors for ROPincluding platelet count was evaluated by using logistic regression. Results: Birth weight (BW), gestational age (GA), and low platelet count in the first week after birth were significant risk factorsfor developing ROP (p=0.038, 0.02, and 0.004, respectively). BW, GA, ventilation, and lower platelet count were associated withprogression to type 1 ROP (p=0.004; 0.027, and 0.021, respectively). Conclusion: Lower platelet count in the first week after birth is a risk factor for ROP development in addition to the previouslyestablished factors of ventilation need, low BW, and low GA.

Özet

Amaç: Çalışmamızın amacı, prematüre retinopatisi (PR) gelişimine sebep olabilecek bilinen risk faktörlerine ek olarak trombosit sayısının PR gelişimine etkisini araştırmaktı.Gereç ve Yöntem: Retrospektif olarak planlanan çalışmada 137 yenidoğan, üç alt grupta incelendi: PR gelişmeyen; hafif PR ve lazer tedavisi gerektiren ağır PR (tip 1 PR). Hasta kayıtları retrospektif olarak incelendi ve trombosit sayısını da içeren PR gelişimi için olası risk faktörleri lojistik regresyon analizi kullanılarak istatistiksel olarak incelendi.Bulgular: Doğum ağırlığı (DA), doğum haftası (DH) ve doğumdan sonraki ilk hafta içinde düşük trombosit sayısı PR gelişimi için risk faktörleri olarak saptandı (sırasıyla; p=0,038, 0,02 ve 0,004). DA, DH, ventilasyon tedavisi ve düşük trombosit sayısı tip 1 PR gelişimi için risk faktörleri olarak belirlendi (sırasıyla; p=0,004; 0,027 ve 0,021).Sonuç: Prematüre retinopatisinde, doğumdan sonraki ilk haftada trombosit sayısının düşük olması, bilinen risk faktörleri olan ventilasyon gerekliliği, düşük DA ve düşük DH’ye ek bir risk faktörüdür.

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Cite This Article

KEŞKEK, N. Ş., GÜLCAN, H., YILMAZ, G., AKKOYUN, İ. (2022). Impact of Platelet Count in Retinopathy of Prematurity. Türk Oftalmoloji Dergisi, Cilt: 50 - Sayı: 6, 351–355. https://ajindex.com/articles/637668

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