Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2014 / Cilt: 25 - Sayı: 2

Microorganisms causing infection in congenital nasolacrimal duct obstruction and antibiotic sensitivity

Doğuştan nazolakrimal kanal tıkanıklığında enfeksiyona sebep olan mikroorganizmalar ve antibiyotik duyarlılıkları

Pages
107–111
Publication Date
2022-10-17
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Tetracyclines and quinolones were effective in vitro agents against infections caused by con genital nasolacrimal duct obstruction

📌 3 Key Takeaways

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Objective & Hypothesis:Background:The aim of this study was to evaluate the micro bial pathogens and their susceptibilities to antibiotics in chil dren aged 12 months and younger with congenital nasolacri mal duct obstruction.
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Key Findings & Data:Methods:Forty eyes of 40 children with congenital nasolac rimal duct obstruction were enrolled in the study.
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Conclusion & Impact:Tetracyclines and quinolones were effective in vitro agents against infections caused by con genital nasolacrimal duct obstruction
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background:The aim of this study was to evaluate the micro bial pathogens and their susceptibilities to antibiotics in chil dren aged 12 months and younger with congenital nasolacri mal duct obstruction. Methods:Forty eyes of 40 children with congenital nasolac rimal duct obstruction were enrolled in the study. Samples obtained from mucopurulent discharge were cultured onto blood, chocolate, and eosin-methylene blue agars. Gram stain ing was performed for positive cultures after twenty-four hours of incubation period. Identification of the microorganism and susceptibility test was done by Vitek device (BioMerieux, France). Minimal inhibitor concentration method was used for the susceptibility test. Results:Cultures were positive for bacteria in 26 (65%) of the samples. Twenty-three (85.2%) of the isolated microorganism were gram-positive and 4 (14.8%) were gram-negative. The most frequently isolated microorganisms were Streptecoccus pnemonia (29.6%) and Staphylococcus aureus (11.1%). The most effective drugs were vancomycine (100%), trimethoprim/ sulfamethoxazole (TMP-SMZ) (82.6%) and levofloxacin (78.2%) for Gram-positive bacteria and TMP-SMZ (100%), ciprofloxacin (100%) and gentamicin (100%) for Gram-negative bacteria. Conclusion:IIn our study, the most frequently isolated micro organisms were gram-positive. Tetracyclines and quinolones were effective in vitro agents against infections caused by con genital nasolacrimal duct obstruction

Özet

Amaç:Amaç; doğuştan nazolakrimal kanal tıkanıklığı olan bir yaş altı olgularda, enfeksiyona neden olan mikroorganiz maları ve antibiyotik duyarlılıklarını incelemektir. Gereç ve Yöntem: Doğuştan nazolakrimal kanal tıkanıklığı olan, bir yaş altındaki 40 olgunun 40 gözü çalışmaya alındı. Mükopürülan akıntıdan alınan örneklerden kanlı agar, çiko lata agar ve eozin-metilen mavili agara ekim yapıldı. Yirmi dört saatlik inkübasyon süresinden sonra pozitif kültürler den gram boyama yapıldı. Bakteri tanımlanması ve antibiyo tik duyarlılık testi Vitek cihazı (BioMerieux, Fransa) kullanıla rak yapıldı. Antibiyotik duyarlılık testi için minimal inhibitör konsantrasyon yöntemi kullanıldı. Bulgular:Kültür örneklerinin 26’sında (%65) üreme sap tandı. İzole edilen mikroorganizmaların 23’ü (%85.2) gram- pozitif, dördü (%14.8) gram-negatif idi. En fazla izole edilen mikroorganizma Streptecoccus pnemonia (%29.6) veStaphylococcus aureus (%11.1)’tu. Vankomisin (%100), tri metoprim/sulfometoksazol (TMP-SMZ) (%82.6), levofloksa sin (%78.2) gram-pozitif bakterilere en etkili antibiyotikler iken; TMP-SMZ (%100), siprofloksasin (%100) ve gentamisin (%100) gram-negatif bakterilere en etkili antibiyotikler ola rak tespit edildi. Sonuç:Çalışmamızda en sık gram-pozitif mikroorganizmalar izole edildi. Tetrasiklin ve kinolon grubu antibiyotiklerin nazolakrimal kanal tıkanıklığında oluşan enfeksiyonlarda invitro olarak etkili ajanlar olduğu belirlendi.

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Cite This Article

ÖZYAZICI, G., KEŞKEK, Ş. Ö., ŞAHİNOĞLU, N. K., CEVHER, S., KAYIKLIK, A. (2022). Microorganisms causing infection in congenital nasolacrimal duct obstruction and antibiotic sensitivity. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 25 - Sayı: 2, 107–111. https://ajindex.com/articles/571394

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