Journals / Türk Kardiyoloji Derneği Arşivi / 2002 / Cilt: 30 - Sayı: 10

Effect of acute blood pressure reduction on oxygen kinetic values in hypertensive cases

Hipertansif olgularda kan basıncındaki akut azalmanın oksijen kinetik değerlerine etkisi

Pages
612–615
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This is in support of the concept that the heart adapts to exercise more easily and performs the same amount of work with less energy and this underlines the importance of blood pressure control.

📌 3 Key Takeaways

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Objective & Hypothesis:Exercise tests performed at the submaximal level are valuable in the evaluation of complaints during daily activities.
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Key Findings & Data:Patients performed exercise tests with modified Bruce protocol for 6 minutes upon which blood pressures rose to 183±13 mmHg systolic and 94±9 mmHg diastolic levels.
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Conclusion & Impact:This is in support of the concept that the heart adapts to exercise more easily and performs the same amount of work with less energy and this underlines the importance of blood pressure control.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Exercise tests performed at the submaximal level are valuable in the evaluation of complaints during daily activities. Fatigue and shortness of breath are among the common complaints of most hypertensive patients during daily activities. We aimed to evaluate this the effects of blood pressure control on oxygen kinetic values. Twenty-eight patients with uncontrolled blood pressure were included. Patients performed exercise tests with modified Bruce protocol for 6 minutes upon which blood pressures rose to 183±13 mmHg systolic and 94±9 mmHg diastolic levels. Oral captopril administration reduced these readings to 133±8 mmHg and 84±5 mmHg, respectively. Variability in oxygen kinetic values (oxygen deficit and mean response time) between both tests was investigated. Oxygen deficit values and the mean response time measured during the exercise tests, which the patients performed at a constant velocity and when their blood pressures were high, were found to be 511±138 mililiters (ml) and 44±12 seconds (sec), respectively. During the second exercise tests performed after blood pressure reduction with captopril, oxygen deficit and mean response time to exercise were 397±126 ml and 36±9 sec respectively. The difference was statistically significant (p=0.0001, p=0.001). Hence, there is a significant improvement in oxygen kinetic values in the early period with normalization of blood pressure. This is in support of the concept that the heart adapts to exercise more easily and performs the same amount of work with less energy and this underlines the importance of blood pressure control.

Özet

Günlük aktivitelerimiz sırasında oluşan şikayetlerimizin değerlendirilmesinde submaksimal seviyede uygulanan egzersiz testleri değerlidir. Bilindiği gibi çoğu hipertansif olguda günlük aktiviteler sırasında çabuk yorulma ve nefes darlığı yakınması bulunmaktadır. Çalışmamızda kan basıncı kontrolünün oksijen kinetik değerleri üzerinde yarattığı etkileri değerlendirmeyi amaçladık. Kontrolsüz yüksek tansiyonlu toplam 28 olgu çalışmaya dahil edildi. Bu olgular kan basınç değerleri yüksek iken; sistolik kan basıncı (SKB): 183±13 mmHg, diyastolik kan basıncı (DKB): 94±9 mmHg ve kaptopril ile kan basıncı değerleri düşürüldükten sonra SKB: 133±8 mmHg, DKB:84±5mmHg modifiye Bruce protokolü 2. kademede iki kez birer saat arayla, 6 dakika süre ile yürütüldü. Olgularda her iki test arasındaki oksijen kinetik değerlerindeki (oksijen "defisit" ve ortalama yanıt süresi) değişkenlik araştırıldı. Olguların kan basıncı değerleri yüksek iken sabit hızda yaptıkları efor testi sırasında ölçülen oksijen "defisit" değeri 511±138 mililitre (ml), efora verilen ortalama yanıt süresi ise 44±12 saniye (sn) olarak bulundu. Kaptopril ile kan basıncı değerleri düşürüldükten sonra yapılan ikinci testte ölçülen oksijen "defisit" değeri 397±126 ml, ortalama yanıt süresi ise 36±9 sn bulundu. Aradaki fark istatistiki açıdan anlamlı bulundu (p=0.0001, p=0.001). Çalışma bulgularımıza göre kan basıncının normal seviyelere indirilmesi ile, erken dönemde oksijen kinetik değerlerinde belirgin iyileşme görülmektedir. Bu durum, egzersize kalbin daha kolay uyum sağladığını ve aynı iş yükünü daha düşük enerji ile gerçekleştirdiğini göstermekte ve kan basıncı kontrolünün önemini bir kez daha kanıtlamaktadır.

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Cite This Article

DAYİ, Ü. Ş., ZOR, A., TERZİ, S., TAYYARECİ, G., AKSOY, Ş., TANGÜREK, B., AKBULUT, T., AKGÖZ, H., DAĞ, Ö. (2022). Effect of acute blood pressure reduction on oxygen kinetic values in hypertensive cases. Türk Kardiyoloji Derneği Arşivi, Cilt: 30 - Sayı: 10, 612–615. https://ajindex.com/articles/633943

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