Journals / Türk Anestezi ve Reanimasyon Dergisi / 2008 / Cilt: 36 - Sayı: 4

The comparison of the effects of low and high flow desflurane anesthesia on hemodynamic effects and anesthetic gas consumption

Düşük ve yüksek akımlı desfluran anestezisinin hemodinamiye ve anestezik gaz tüketimine etkilerinin karşılaştırılması

Pages
222–229
Publication Date
2022-11-05
DOI
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The O2, N2O and desflurane consumptions of Group N were lower than those of Group N. (p

📌 3 Key Takeaways

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Objective & Hypothesis:We investigated the effects of desflurane anesthesia with high and low fresh gas flows on hemodynamic stability and desflurane consumption.
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Key Findings & Data:After obtaining ethical comittee approval, 60 patients in the ASA risk groups I-II were included in the study.
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Conclusion & Impact:The O2, N2O and desflurane consumptions of Group N were lower than those of Group N. (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

We investigated the effects of desflurane anesthesia with high and low fresh gas flows on hemodynamic stability and desflurane consumption. After obtaining ethical comittee approval, 60 patients in the ASA risk groups I-II were included in the study. After anesthesia induction, the anesthesia maintenance was performed during the first 10 minutes with 4,4 L min-1 fresh gas flow and desflurane (4-6 %) in all cases. The fresh gas flow was reduced to 1 L min-1 after 10 minutes whereas it was maintained as 4,4 L min-1 in Group N after the randomization of the patients into two groups. Heart rate (HR), mean arterial pressure (MAP), peripheral O2 saturation (SPO2), inspiratory desflurane (FiDes), expiratory desflurane (ETDes), inspiratory O2 (FiO2), inspiratory CO2 (FiCO2), expiratory O2 (ETO2), inspiratory N2O (FiN2O), expiratory N2O (ETN2O), end-tidal CO2 concentrations (ETCO2) and peak airway pressure (Pplateau) values were measured and recorded at 0., 2., 5., 7. and 10. minutes after intubation and every 5 minutes in first 60 minutes and every 15 minutes later on. The total amounts of fentanyl, desflurane, N2O and O2 were also recorded. There were no significant differences between the groups in terms of HR, MAP, FiDes, ETDes, ETCO2, Pplateau and total fentanyl consumption. The O2, N2O and desflurane consumptions of Group N were lower than those of Group N. (p

Özet

Çalışmada, düşük ve yüksek taze gaz akımları ile uygulanan desfluran anestezisinin hemodinami ve desfluran tüketimi üzerine etkileri araştırıldı. Etik Kurul onayı alındıktan sonra, çalışmaya, ASA I-II risk grubundaki 60 olgu alındı. Tüm olgularda anestezi indüksiyonundan sonra, anestezi uygulaması, ilk 10 dk. taze gaz akımı 4,4 L dk-1 ve % 4-6 desfluran ile sürdürüldü. Randomize olarak iki gruba ayrıldıktan sonra taze gaz akımı Grup N’de 4,4 L dk-1, Grup D’de ise 10. dk.’dan sonra 1 L dk-1’ya indirildi. Kalp atım hızı (KAH), ortalama arteriyel basınç (OAB), periferik O2 satürasyonu (SpO2), inspiratuvar desfluran (FiDes), ekspiratuvar desfluran (ETDes), inspiratuvar O2 (FiO2), inspiratuvar CO2 (FiCO2), ekspiratuvar O2 (ETO2), inspiratuvar N2O (FiN2O), ekspiratuvar N2O (ETN2O), soluk sonu karbondioksit (ETCO2) konsantrasyonları ve hava yolu plato basıncı (Pplato) değerleri entübasyon sonrası 0., 2., 5., 7., 10. dk.’larda ve sonrasında 5’er dk. arayla ve 60. dk.’dan sonra 15 dk. arayla kaydedildi. Ayrıca fentanil, desfluran, N2O ve O2’nin toplam tüketim miktarları da kaydedildi. KAH, OAB, FiDes, ETDes, ETCO2, Pplato değerleri ve fentanil tüketimi açısından gruplar arasında fark yoktu. Grup D’de O2, N2O ve desfluran tüketiminin Grup N’ye göre daha düşük olduğu saptandı (p

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Cite This Article

TURAN, I. Ö., AYOĞLU, H., YURTLU, S., ÖZER, Y., ÇUKDAR, G., HANCI, V. (2022). The comparison of the effects of low and high flow desflurane anesthesia on hemodynamic effects and anesthetic gas consumption. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 36 - Sayı: 4, 222–229. https://ajindex.com/articles/619967

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