SavedAdd your journal

Journals / Türk Anestezi ve Reanimasyon Dergisi / 2009 / Cilt: 37 - Sayı: 1

The effects of ıntrathecal levobupivacaine and opioid combinations in caesarean operations

Sezaryen operasyonlarında intratekal levobupivakaine eklenen fentanil ve morfin kombinasyonlarının etkilerinin karşılaştırması

Işıl Özkoçak TURAN
B.Serhan YURTLU
R.Dilek OKYAY
Süleyman AKAY
Hilal AYOĞLU
Pages
25–34
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Parturients randomized into four groups and Group L received 12 mg 0.5% levobupivacaine, Group LF received 10 mg 0.5% + 12.5 µg fentanyl, Group LM received 11 mg 0.5% levobupivacaine + 100 µg morphine and Group LFM received 11 mg 0.5 % levobupivacaine + 5 µg fentanyl + 50 µg morphine intrathecally.Results: Haemodynamics were affected much more in groups which included fentanyl and sensorial block level raised up faster (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: We aimed to investigate the effects of levobupivacaine, fentanyl and morphine’s different intrathecal combinations on parturients planned to have elective caesarean operation with spinal anesthesia.
📊
Key Findings & Data:We have also investigated the effects of these combinations on newborns.
💡
Conclusion & Impact:Parturients randomized into four groups and Group L received 12 mg 0.5% levobupivacaine, Group LF received 10 mg 0.5% + 12.5 µg fentanyl, Group LM received 11 mg 0.5% levobupivacaine + 100 µg morphine and Group LFM received 11 mg 0.5 % levobupivacaine + 5 µg fentanyl + 50 µg morphine intrathecally.Results: Haemodynamics were affected much more in groups which included fentanyl and sensorial block level raised up faster (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: We aimed to investigate the effects of levobupivacaine, fentanyl and morphine’s different intrathecal combinations on parturients planned to have elective caesarean operation with spinal anesthesia. We have also investigated the effects of these combinations on newborns. Material and Methods: One hundred and twenty parturients of ASA physical status I-II planned to have Caesarean operation enrolled in the study. Parturients randomized into four groups and Group L received 12 mg 0.5% levobupivacaine, Group LF received 10 mg 0.5% + 12.5 µg fentanyl, Group LM received 11 mg 0.5% levobupivacaine + 100 µg morphine and Group LFM received 11 mg 0.5 % levobupivacaine + 5 µg fentanyl + 50 µg morphine intrathecally.Results: Haemodynamics were affected much more in groups which included fentanyl and sensorial block level raised up faster (p

Özet

Amaç: Çalışmamızda, spinal anestezi ile elektif sezaryen operasyonu planlanan gebelerde; levobupivakain, fentanil ve morfin kullanılarak hazırlanan farklı intratekal kombinasyonların anne ve yeni doğan üzerine etkilerinin araştırılması amaçlandı. Gereç ve Yöntem: Sezaryen operasyonu planlanan, ASA I-II grubundan 120 gebe çalışmaya alındı. Randomize, dört gruba ayrılan olgulardan Grup L’ye (n=30) 12 mg % 0,5 levobupivakain, Grup LF’ye (n=30) 10 mg % 0,5 levobupivakain + 12,5 µg fentanil, Grup LM’ye (n=30) 11 mg % 0,5 levobupivakain + 100 µg morfin, Grup LFM’ye (n=30) 11 mg % 0,5 levobupivakain + 5 µg fentanil + 50 µg morfin intratekal uygulandı. Bulgular: Fentanil eklenen gruplarda hemodinami daha fazla etkilendi ve duyusal blok düzeyi daha hızlı yükseldi (p

🔖

Cite This Article

TURAN, I. Ö., YURTLU, B., OKYAY, R., AKAY, S., AYOĞLU, H. (2022). The effects of ıntrathecal levobupivacaine and opioid combinations in caesarean operations. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 37 - Sayı: 1, 25–34. https://ajindex.com/articles/619942

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Tekin İ, Laçin S, Arıcan İ, Ok G. Sezaryen operasyonu geçirmiş olguların ‘‘anestezi yöntemi’’nin seçimi üzerine etkileri. Türkiye Klinikleri Anesteziyoloji Reanimasyon Dergisi 2005; 3:1-6
  2. Glaser C, Marhofer P, Zimpfer G, et al. Levobupivacaine versus racemic bupivacaine for spinal anesthesia. Anesth Analg 2002; 94:194-8
  3. Şahin Ş. Sezaryende postoperatif ağrı. In: Şahin Ş, Owen MD (eds). Ağrısız Doğum ve Sezaryende Anestezi. İstanbul: Nobel&Güneş Kitabevi 2006, 125-32
  4. Dahl JB, Jeppesen IS, Jorgensen H, Wetterslev J, Møiniche S. Intraoperative and postoperative analgesic efficacy and adverse effects of intrathecal opioids in patients undergoing cesarean section with spinal anesthesia: a qualitative and quantitative systematic review of randomized controlled trials. Anesthesiology 1999; 91:1919-27
  5. Rosaeq OP, Lui AC, Cicutti NJ et al. Peri-operative multi-modal pain therapy for ceasarean section: analgesia and fitness for discharge. Can J Anaesth 1997; 44:803-9
  6. Gadsden J, Hart S, Santos AC. Post-cesarean delivery analgesia. Anesth Analg 2005; 101:62-9
  7. Hamber EA, Viscomi CM. Intrathecal lipophilic opioids as adjuncts to surgical spinal anesthesia. Reg Anesth Pain Med 1999; 24:255-63
  8. Bogra J, Arora N, Srivastava P. Synergistic effect of intrathecal fentanyl and bupivacaine in spinal anesthesia for cesarean section. BMC Anesthesiol 2005; 5:5
  9. Wall PD, Mellzack R. Tedavi Yaklaşımları. In: Wall PD, Mellzack R (eds). Ağrı Tedavisi El Kitabı. Çeviri Editörü: Erdine S. Ankara: Churchill Livingstone & Güneş kitabevi; 2006, 341-544
  10. Kestin IG. Spinal anaesthesia in obstetrics. Br J Anaesth 1991; 66:596-607
  11. Hunt CO, Naulty JS, Bader AM et al. Perioperative analgesia with subarachnoid fentanyl-bupivacaine for cesarean delivery. Anesthesiology 1989; 71:535-40
  12. Belzarena SD. Clinical effects of intrathecally administered fentanyl in patients undergoing cesarean section. Anesth Analg 1992; 74:653-7
  13. Coda BA. Opioids. In: Barash PG, Cullen BF, Stoelting RK (eds). Clinic Anesthesia. Fourt edition. Philadelphia: Lippincott Williams&Wilkins 2001; 14:345-75
  14. Van de Velde M, Van Schoubroeck D, Jani J et al. Combined spinal-epidural anesthesia for cesarean delivery: dose-dependent effects of hyperbaric bupivacaine on maternal haemodynamics. Anesth Analg 2006; 103:187-90
  15. Dahlgren G, Hultstrand C, Jakobsson J et al. Intrathecal sufentanil, fentanyl, or placebo added to bupivacaine for cesarean section. Anesth Analg 1997; 85:1