Journals / Türk Anestezi ve Reanimasyon Dergisi / 2008 / Cilt: 36 - Sayı: 2

A comparison of general anesthesia with general anesthesia plus epidural levobupivacaine or bupivacaine

Genel anestezi ve genel anestezi ile birlikte uygulanan epidural levobupivakain veya bupivakain anestezisinin karşılaştırılması

Pages
105–113
Publication Date
2022-11-05
DOI
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Total remifentanil, sevoflurane and neuromusculer blocker requirements were greater in Group III compared to other two groups (p

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Objective & Hypothesis:Aim: In this study, we aimed to compare the effects of general anesthesia and general anesthesia combined with epidural anesthesia, using two different local anesthesics levobupivacane or bupivakaine on the response to surgical stress, intraoperative hemodynamics, recovery, advers effects and postoperative analgesia.Materials and Methods: Fiftyfour patients scheduled for TAH-BSO were randomly divided into three groups,.
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Key Findings & Data:Anesthesia was induced in Group I and Group II, after T6 sensorial block were achieved.
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Conclusion & Impact:Total remifentanil, sevoflurane and neuromusculer blocker requirements were greater in Group III compared to other two groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: In this study, we aimed to compare the effects of general anesthesia and general anesthesia combined with epidural anesthesia, using two different local anesthesics levobupivacane or bupivakaine on the response to surgical stress, intraoperative hemodynamics, recovery, advers effects and postoperative analgesia.Materials and Methods: Fiftyfour patients scheduled for TAH-BSO were randomly divided into three groups,. General anesthesia+epidural bupivacaine group (Group I), general anesthesia+epidural levobupivacaine group (Group II) and general anesthesia group (Group III) were assigned. Lomber epidural catheter was placed in Group I and Group II. Anesthesia was induced in Group I and Group II, after T6 sensorial block were achieved. Anaesthesia induction was performed with propofol 2 mg kg-1, remifentanil 1 µ kg-1 min-1 and rocuronium 0.6 mg kg-1, in all groups. Anaesthesia maintanence was provided with in 50 % O2-air, 1 % sevoflurane and 0.1 µg kg-1 min-1 remifentanil infusion. Blood glucose, cortisol, insulin and CRP were measured. Preoperatively and postoperative 1st and 24th hours. All patients assessed in terms of hemodynamic values, the levels of sensorial and motor block, total dose of sevoflurane and remifentanil used intraoperatively, recovery, VAS and side effects. Epidural bupivacaine+morphine patient controlled analgesia (PCA) was used in Group I, epidural levobupivacaine+morphine PCA was used in Group II and iv morphine PCA was used in Group III, for postoperative pain management.Results: There were no significant diffirences between Group I and Group II in terms of time to reach to T6 dermatome, maximum sensorial block level, and motor block (p>0.05). Total remifentanil, sevoflurane and neuromusculer blocker requirements were greater in Group III compared to other two groups (p

Özet

Amaç: Cerrahi travmaya karşı oluşacak stres yanıtın baskılanması, intraoperatif hemodinami ve postoperatif analjezi kalitesi yönünden; genel anesteziye eklenen epidural bupivakain veya levobupivakain anestezisi ile genel anesteziyi karşılaştırılmayı amaçladık.Gereç ve Yöntem: Çalışmaya total abdominal histerektomi bilateral salpingoooferektomi (TAH-BSO) planlanan 54 vaka kabul edildi. Olgular genel anestezi+epidural bupivakain (Grup I), genel anestezi+epidural levobupivakain (Grup II) ve genel anestezi (Grup III) uygulanan grup şeklinde randomize olarak 3 gruba ayrıldı. Monitorizasyon sonrası Grup I ve Grup II’ye lomber epidural kateter yerleştirilerek, duyusal blok seviyesi T6 dermatomuna ulaştığında 2 mg kg-1 propofol, 1 µ kg-1 dk-1 remifentanil, 0.6 mg kg-1 rokuronyum ile genel anestezi uygulandı. Grup III’e de monitorizasyon sonrası aynı şekilde indüksiyon sağlandı. Anestezi idamesi tüm gruplarda % 50 O2-% 50 hava karışımı içinde %1 sevofluran ve 0.1 µg kg-1 dk-1 remifentanil infüzyonu ile sağlandı. Glukoz, kortizol, insülin, C reaktif protein (CRP) analizi için preoperatif, postoperatif 1. ve 24. saatlerde kan örnekleri alındı. Olgular; hemodinami, duyusal ve motor blok seviyeleri, kullanılan anestezik miktarları, anesteziden derlenme, postoperatif ağrı ve yan etkiler açısından takip edildi. Postoperatif ağrı tedavisi için; Grup I’e epidural bupivakain+morfin, Grup II’ye epidural levobupivakain + morfin ile hazırlanan hasta kontrollü analjezi (HKA), Grup III’e iv morfin HKA uygulandı.Bulgular: Grup I ve II arasında duyusal bloğun T6 dermatomuna ulaşma zamanı, duyusal blok üst seviyesi ve motor blok açısından farklılık tespit edilmedi (p>0.05). Perioperatif kullanılan remifentanil ve sevofluran toplam dozları ve ilave kas gevşetici gereksinimi Grup III’te, Grup I ve II’ye göre anlamlı olarak daha yüksekti (p

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Cite This Article

OTELCİOĞLU, Ş., ÇALIMLI, S., EROL, A., TAVLAN, A., TOPAL, A. (2022). A comparison of general anesthesia with general anesthesia plus epidural levobupivacaine or bupivacaine. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 36 - Sayı: 2, 105–113. https://ajindex.com/articles/619959

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