Journals / Selçuk Tıp Dergisi / 2003 / Cilt: 19 - Sayı: 1

Comparison of recovery characteristics of desflurane and isoflurane in pediatric anesthesia

Çocuklarda desfluran ve isofluran anestezisinin derlenme özelliklerinin karşılaştırılması

Pages
27–32
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, desflurane provides a faster recovery than isoflurane in short-term surgery on children.

📌 3 Key Takeaways

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Objective & Hypothesis:The study compares the recovery charecteristics of desflurane and isoflurane in children undergoing tonsillectomy and/or adenoidectomy.
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Key Findings & Data:Forty children 4-12 year of age were studied and thirty minutes prior to the induction of anesthesia, all patients received 0.5 mg/kg midazolam orally.
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Conclusion & Impact:As a result, desflurane provides a faster recovery than isoflurane in short-term surgery on children.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Çocuk · Cerrahi işlemler · operatif

Abstract

The study compares the recovery charecteristics of desflurane and isoflurane in children undergoing tonsillectomy and/or adenoidectomy. Forty children 4-12 year of age were studied and thirty minutes prior to the induction of anesthesia, all patients received 0.5 mg/kg midazolam orally. They were randomly assigned to receive 1-1.5 % isoflurane (group I) and 6-7 % desflurane (group II) for maintenance of anesthesia after patients given 2-2.5 mg/kg propofol and 10 $mu$g/kg alfentanyl for anesthesia induction. Before surgery, patients received 20 mg/kg paracetamol rectally for postoperative analgesia. Dexamethasone 150 $mu$g/kg was given to reduce the incidence of postoperative nausea and vomiting. Administration of anesthetic agents was terminated at the end surgery. At the end of operation extubation and recovery time determined. Extubation time was defined as the time from discontinuation of anesthetics to extubation. Recovery time was measured from the time the anesthetics were discontinued until the patients achieved a score of 8 on the Aldrete score. Agitation was evaluated by using the three-point score. Extubation and recovery time were significantly faster in the desflurane group than isoflurane group (p<0.05). Incidence of agitation was similar for both groups. As a result, desflurane provides a faster recovery than isoflurane in short-term surgery on children.

Özet

Bu çalışmada tonsillektomi ve/veya adenoidektomi geçiren çocuklarda desfluran ve isofluranın derlenme özellikleri karşılaştırıldı. Yaşları 4-12 olan 40 çocuk çalışmaya alındı ve anestezi indüksiyonundan 30 dk. önce 0.5 mg/kg midazolam oral uygulandı. Anestezi indüksiyonu için 2;2.5 mg/kg propofol ve 10 $mu$g/kg alfentanil verildikten sonra hastalar randomize olarak iki gruba ayrıldı ve anestezi idamesi için % 1-1.5 isofluran (grup 1) ve % 6-7 desfluran (grup II) uygulandı. Cerrahi başlamadan önce, hastalara postoperatif analjezi için 20 mg/kg parasetamol rektal uygulandı. Postoperatif bulantı-kusma insidansını azaltmak için 150 $mu$g/kg deksametason verildi. Anestezik ajanlar operasyon bitiminde kesildi. Ekstübasyon ve derlenme zamanı saptandı. Ekstübasyon zamanı anestezik gazların kesiminden, ekstübasyona kadar geçen süre; derlenme zamanı anestezik gazların kesiminden Aldret skoru 8 oluncaya kadar geçen süre olarak tanımlandı. Ajitasyon üç puanlı skorlama ile değerlendirildi. Ekstübasyon ve derlenme zamanı desfluran grubunda isofluran grubuna göre anlamlı olarak kısa bulundu. Ajitasyon insidansı iki grupta benzerdi. Sonuç olarak, çocuklarda kısa süreli cerrahi girişimlerde desfluran, isoflurana göre daha hızlı derlenme sağlamaktadır.

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Cite This Article

TUNCER, S., YOSUNKAYA, A., TAVLAN, A., UZUN, S., REİSLİ, R., OTELCİOĞLU, Ş. (2003). Comparison of recovery characteristics of desflurane and isoflurane in pediatric anesthesia. Selçuk Tıp Dergisi, Cilt: 19 - Sayı: 1, 27–32. https://ajindex.com/articles/319388

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References (16)

  1. Roige J, Canet J. Desflurane: a new inhalation anesthetic. Rev Esp Anesthesiol Reanim 1996;43:249-54
  2. Dupant J, Tavemier B, Ghosez Y, et al. Recovery after anaesthesia for pulmonary surgery: deflurane, sevoflurane and isoflurane. Br J Anaesth 1999;82:355-9
  3. Rampil I, Lockhart S, Zwass M, Eger El II, Weiskopf RB, Damask MC. Clincal characteristics of desflurane in surgical patients: minimum alveolar concentration. Anesthesiology 1991;74:429-33
  4. Stevens W, Dolan W, Gibbons R, et al. Minimum alveoler concentrations (MAC) of isoflurane with and without nitrous oxide in patients of various ages. Anesthesioiogy 1975;42:197-200
  5. Olson GL. Inhalational anesthesia at the extremes of age: peadiatric anaesthesia. Anaesthesia 1995;50:34-6
  6. Cohen IT, Hannallah RS, Hummer KA. The incidence of emergence agitation associated with desfiurane anesthesia in children is reduced by fentanyl. Anesth Analg 2001;93:88-91
  7. Aldrete JA, Kroulik D. Postanestetic recovery score. Anesth Analg 1970;49:924-34
  8. Davis PJ, Cohen IT, McGowan FX Jr Latta K. Recovery characteristics of desfiurane versus halothane for maintenance of anesthesia in peadiatric ambulatory patients. Anesthesiology 1994;80:298-302
  9. Lerman J. Sevoflurane and desflurane in paediatric patients. Curr Opin Anaesth 1993;6:527-31
  10. Esener Z. Bebeklerde Anestezi. Anestezi Dergisi 1993;1:49-54
  11. Baykara N, Kılıçkan L, Indelen S, Karabey F, Toker K. Günübirlik ameliyatlarda Propofol ve Sevofluran anestezilerinin uyanma süresi ve postoperatif kusma insidansı yönünden karşılaştırılması. Türk Anest Rean Cem Mecmuası 1998;26:387-91
  12. Welborn LG, Hannallah RS, Norden JM, Ruttimann UE, Callan CM. Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in pediatric ambulatory patients. Anesth Analg 1996;83:917-20
  13. Tsai SK, Lee C, Kwan WF, Chen BJ. Recovery of cognitive functions after anaesthesia with desflurane or isofluraneand nitrous oxide. Br J Anaesth 1992;69:255-8
  14. Fletcher JE, Sebel PS, Murphy MR, Smith CA, Mick SA, Flister MP. Psychomotor performance after desflurane anesthesia: A comparison with isoflurane. Anesth Analg 1991;73:260-5
  15. Wilhelm W, BernerK, Grundmann U, PalzM, Larsen R. Desflurane or isoflurne for pediatric ENT anaesthesia. A comparison of intubating conditions and recovery profile Anaesthesist 1998;47:975-8
  16. Grundmann U, Uth M, Eichner A, Wilhelm W, Larsen R. Total intravenous anaesthesia with propofol and remifentanil