Journals / Türk Anestezi ve Reanimasyon Dergisi / 2008 / Cilt: 36 - Sayı: 3

The effects of bispectral index monitoring on end-tidal desflurane concentration and desflurane consumption

Bispektral indeks monitorizasyonunun end-tidal desfluran konsantrasyonu ve desfluran tüketimi üzerine etkisi

Pages
147–152
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The desflurane consumption was total 917.84±14.08 mL and 838.02±11.73 mL in Group I and II, respectively.Conclusion: These findings indicate that the use of BIS, as it decreases the end-tidal concentration of desflurane and desflurane consumption, has become a technique which determines the depth of anesthesia safely.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The Effects of Bispectral Index Monitoring on End-Tidal Desflurane Concentration and Desflurane ConsumptionAim: The aim of the study is to assess whether the concentration of end-tidal desflurane decreases or not with the use of bispectral index (BIS) monitoring to standard anesthetic practice.
📊
Key Findings & Data:Materials and Methods: In all patients anesthesia was induced with thiopental sodium 5 mg kg-1 and fentanyl 1 µg kg-1.
💡
Conclusion & Impact:The desflurane consumption was total 917.84±14.08 mL and 838.02±11.73 mL in Group I and II, respectively.Conclusion: These findings indicate that the use of BIS, as it decreases the end-tidal concentration of desflurane and desflurane consumption, has become a technique which determines the depth of anesthesia safely.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The Effects of Bispectral Index Monitoring on End-Tidal Desflurane Concentration and Desflurane ConsumptionAim: The aim of the study is to assess whether the concentration of end-tidal desflurane decreases or not with the use of bispectral index (BIS) monitoring to standard anesthetic practice. Materials and Methods: In all patients anesthesia was induced with thiopental sodium 5 mg kg-1 and fentanyl 1 µg kg-1. The trachea was intubated using vecuronium 0.1mg kg-1. Anesthesia was maintained with desflurane, in a mixture of nitrous oxide 1L min-1 and oxygen 1 L min-1. Desflurane with 4-6 % concentration was administered to patients for 5 min after tracheal intubation. Additional fentanyl 1 µg kg-1 was given before skin insicion and no more was given. The desflurane concentration was then changed as follows: In Group I; if the patients displayed clinical signs consistent with inadequate anesthesia, the inspired desflurane concentration was increased or decreased by 1 %. In Group II, the anesthesiologist adjusted the concentration of desflurane to achieve a target BIS in the range of 50±5. Results: The mean BIS value was 35.98±2.3 and 45.68±5.3 in Group I and II, respectively. BIS levels in Group I were significantly lower during surgery (p=0.001). The end tidal desflurane concentrations in Group I were significantly higher than Group II (Group I: 4.61±0.48, Group II: 3.92±0.61) (p=0.007). The desflurane consumption was total 917.84±14.08 mL and 838.02±11.73 mL in Group I and II, respectively.Conclusion: These findings indicate that the use of BIS, as it decreases the end-tidal concentration of desflurane and desflurane consumption, has become a technique which determines the depth of anesthesia safely.

Özet

Amaç: Bu çalışmada, genel anestezi uygulamalarında BIS monitorü kullanımı ile end-tidal desfluran konsantrasyonlarındaki değişimlerin araştırılması planlandı.Gereç ve Yöntem: Çalışmaya ASA I-II grubunda 40 hasta dahil edildi. Anestezi indüksiyonu tüm hastalarda 5 mg kg-1 tiyopental sodyum ve 1 µg kg-1 fentanil ile gerçekleştirildi. Kas gevşemesi ve entübasyon, 0.1 mg kg-1 veküronyum kullanılarak sağlandı. Anestezi idamesinde, 1 L dk-1 oksijen ve 1 L dk-1 nitröz oksit karışımı içinde desfluran kullanıldı. Hastalara entübasyon sonrasında 5 dk. süre ile % 4-6 desfluran verildi. Cilt insizyonu öncesinde ek olarak 1 µg kg-1 fentanil yapıldı ve ameliyat süresince başka opioid kullanılmadı. Desfluran konsantrasyonu; Grup I’de, hastalarda yetersiz anesteziyi gösteren klinik bulgular oluştuğunda, inspire edilen desfluran konsantrasyonu % 1 artırıldı veya azaltıldı. Grup II’de desfluran konsantrasyonunu BIS değerini 50±5 düzeylerinde tutacak şekilde ayarladı.Bulgular: BIS indeksi ortalama değerleri Grup I’de 35.98±2.3 ve Grup II’de 45.68±5.3 idi. Grup I’de BIS değerleri anlamlı derecede düşük bulundu. Grup I’de end-tidal desfluran konsantrasyonları, Grup II’ye göre anlamlı derecede yüksek bulundu (Grup I: 4.61±0.48, Grup II: 3.92±0.61, p=0.007). Total desfluran tüketimi Grup I’de 917.84±14.08 mL iken, Grup II’de 838.02±11.73 mL olarak hesaplandı.Sonuç: Bu çalışmada, genel anestezi alan hastalarda BIS monitörü kullanımının, desfluran konsantrasyonlarını ve tüketimini azaltmanın yanında, anestezi derinliğini ölçmede güvenilir bir yöntem olduğu sonucuna varıldı.

🔖

Cite This Article

DİKMEN, B., TAKMAZ, A. S., ÖZCAN, O. A., GÜLHAN, Y., KAYMAK, Ç. (2022). The effects of bispectral index monitoring on end-tidal desflurane concentration and desflurane consumption. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 36 - Sayı: 3, 147–152. https://ajindex.com/articles/619958

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Eger EI II. Desflurane- An overwiev of its properties. Anesthesiology 1993; 20(3):87-92
  2. Smiley RM, Ornstein E, Matteo RS, Pantuck EJ, Pantuck CB. Desflurane and isoflurane in surgical patients: comparison of emergence time. Anesthesiology 1991; 74:425-428
  3. Kissin I. Depth of Anesthesia and Bispectral Index Monitoring. Anesth Analg 2000; 90:1114-1117
  4. Glass PS, Bloom M, Kearse L, Rosow C, Sebel P, Manberg P. Bispectral analysis measures sedation and memory effects of propofol, midazolam, isoflurane and alfentanil in healthy volunteers. Anesthesiology 1997; 86:836-847
  5. Drummond JC. Monitoring depth of anesthesia: with emphasis on the application of the Bispectral Index and the middle latency auditory evoked response to the prevention of recall. Anesthesiology 2000; 93:876-882
  6. Pomfrett CJ. Heart rate variability, BIS and depth of anaesthesia. Br J Anaesth 1999; 82:659-662
  7. Russell IF. Midazolam alfentanil an anesthetic? An investigation using the isolated forearm technique. Br J Anaesth 1996; 70:42-46
  8. Degoute CS, Macabeo C, Dubreuil C, Duclaux R, Banssillon V. EEG bispectral index and hypnotic component of anaesthesia induced by sevoflurane: comparison between children and adults. Br J Anaesth 2001; 86(2):209-212
  9. Chen X, Tang J, White PF, Wender RH, Ma H, Sloninsky A, Kariger R. A comparison of patient state index and bispectral index values during the perioperative period. Anesth Analg 2002; 95:1669-1674
  10. Balcı C, Arıkan Y, Baki E. İntraoperatif sedasyonda propofol ve deksmedetomidinin hemodinami üzerine etkisi ve eşdeğer sedasyon skorlarında bispektral indeks değerlerinin karşılaştırılması. Türk Anest Rean Der Dergisi 2006; 34(4):249-254
  11. Johansen JW, Sebel PS. Development and clinical application of electroencephalographic bispectrum monitoring. Anesthesiology 2000; 93:1336-1344
  12. Yli-Hankala A, Vakkuri A, Annila P, Korttila K. EEG bispectral index monitoring in sevoflurane or propofol anaesthesia: analysis of direct costs and immediate recovery. Acta Anaesth Scand 1999; 43:545-549
  13. Pavlin DJ, Hong JY, Freund PR, Koerschgen ME, Bower JO, Bowdle TA. The effect of bispectral index monitoring on end-tidal gas concentration and recovery duration after outpatient anesthesia. Anesth Analg 2001; 93:613-619
  14. Gan TJ, Glass PS, Windsor A, Payne F, Rosow C, Sebel P, Manberg P. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. Anesthesiolo