Journals / Türk Anestezi ve Reanimasyon Dergisi / 2012 / Cilt: 40 - Sayı: 1

The effect of different oxygen concentratıons used for the ınductıon and maintenance of anesthesia on gas exchange in the lungs

Anestezi indüksiyon ve idamesinde kullanılan farklı oksijen konsantrasyonlarının akciğerdeki gaz değişimine etkisi

Pages
11–19
Publication Date
2022-11-05
DOI
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Except for thebaseline, the highest PaO2 /FiO2ratios were achieved with 0,4 FiO2in air at all estimated time intervals (p

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Objective & Hypothesis:Objective: In this study, we aimed to investigate the effects of different oxygen concentrations used in induction and maintanenceof anesthesia on pulmonary gas exchange in laparoscopic cholecystectomy which entertain the risk of atelectasis.Materials and Methods: After the approval of Ethics Committee of the Institution and informed written consent forms were obta- ined, 75 patients undergoing elective laparoscopic cholecystectomy aged between 19 to 76 years, were randomized into 3 groups.Preoxygenation was performed with 80 % O2to low FiO2groups (Groups A and N) and 100 % O2to high FiO2group (Group O) for 3minutes.
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Key Findings & Data:After induction and maintenance of anesthesia, patients in Group A ventilated with air + 0,4 FiO2 , Group N with N2 O + FiO2 0,4, and Group O with 1 FiO2 .
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Conclusion & Impact:Except for thebaseline, the highest PaO2 /FiO2ratios were achieved with 0,4 FiO2in air at all estimated time intervals (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we aimed to investigate the effects of different oxygen concentrations used in induction and maintanenceof anesthesia on pulmonary gas exchange in laparoscopic cholecystectomy which entertain the risk of atelectasis.Materials and Methods: After the approval of Ethics Committee of the Institution and informed written consent forms were obta- ined, 75 patients undergoing elective laparoscopic cholecystectomy aged between 19 to 76 years, were randomized into 3 groups.Preoxygenation was performed with 80 % O2to low FiO2groups (Groups A and N) and 100 % O2to high FiO2group (Group O) for 3minutes. After induction and maintenance of anesthesia, patients in Group A ventilated with air + 0,4 FiO2 , Group N with N2 O + FiO2 0,4, and Group O with 1 FiO2 . Patients’ blood gas samples were collected before preoxygenation, 30 minutes after CO2insufflation,at PACU and 24 hours after the end of surgery. At the same time intervals, PaO2 /FiO2and P(A-a) O2values were calculated to evaluatethe gas exchange in lungs.Results: Baseline PaO2 /FiO2ratios of patients ventilated with air+FiO20,4 were not different when compared with those obtainedat 30thmin of pneumoperitoneum, PACU, and postoperative 24thhours, respectively. PaO2 /FiO2ratios of Groups O and N weresignificantly worsened especially at the 30thmin of pneumoperitoneum when compared with the baseline values. Except for thebaseline, the highest PaO2 /FiO2ratios were achieved with 0,4 FiO2in air at all estimated time intervals (p

Özet

Amaç: Bu çalışmada, atelektazi açısından risk taşıyan laparoskopik kolesistektomi ameliyatlarında, anestezi indüksiyonunda veidamesinde kullanılan farklı oksijen konsantrasyonlarının, akciğerdeki gaz değişimine olan etkilerinin araştırılması amaçlandı.Gereç ve Yöntem: 19-76 yaş arasında, elektif laparoskopik kolesistektomi ameliyatı geçirecek 75 hasta, hastane etik kurul raporuve yazılı onam formları alındıktan sonra 3 gruba randomize olarak ayrıldı. Preoksijenizasyon, düşük FiO2 kullanılan gruplarda %80 O2 ile, yüksek FiO2kullanılan grupta %100 O2 ile uygulandı. Indüksiyon sonrası genel anestezi sırasında Grup A’daki hastalar hava + 0,4 FiO2 , Grup N’dekiler N2O + 0,4 FiO2, Grup O’daki hastalar ise 1,0 FiO2 , ile ventile edildi. Hastaların preoksijenizasyon öncesi 0. dk.’da,CO2 insüflasyonundan sonraki 30. dk.’da, ASBÜ’da ve operasyon bitiminden sonra 24. saatte kan gazları alındı. Bu zamanlarda PaO2/FiO2değerleri ve P(A-a) O2 değerleri hesaplanarak akciğerdeki gaz değişimleri değerlendirildi.Bulgular: Grup A’da, pnömoperitonyumun 30. dk.’sında, ASBÜ’de ve postoperatif 24. saatte PaO2/FiO2 oranında bazale göre belirgin fark gözlenmezken, Grup O ve Grup N’de özellikle pnömoperitonyumun 30. dk.’sında, PaO2 /FiO2 oranının bazale göre belirginolarak kötüleştiği görüldü (p

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Cite This Article

DİKMEN, B., UYSAL, H. Y., ACAR, H. V., ERUYAR, S., KORKULU, F. (2022). The effect of different oxygen concentratıons used for the ınductıon and maintenance of anesthesia on gas exchange in the lungs. Türk Anestezi ve Reanimasyon Dergisi, Cilt: 40 - Sayı: 1, 11–19. https://ajindex.com/articles/619792

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