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Journals / Turkish Journal of Medical Sciences / 2016 / Cilt: 46 - Sayı: 4

Higher neutrophil to lymphocyte ratio is related to a lower ejection fraction in bicuspid aortic valve patients

Tahir DURMAZ
Abdullah Nabi ASLAN
Murat AKÇAY
Hüseyin AYHAN
Telat KELEŞ
Hacı Ahmet KASAPKARA
Zeynep Şeyma TURİNAY
Murat Can GÜNEY
Engin BOZKURT
Pages
1144–1150
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Results: When the results were compared, it was demonstrated that there was a positive correlation between NLR and ascending aorta diameter (r: 0.485, P = 0.026), whereas there was a negative correlation between NLR and left ventricular end-diastolic diameter (r: 0.475, P = 0.030), left ventricular end-systolic diameter (r: 0.482, P = 0.027), and left ventricular ejection fraction (r: 0.467, P = 0.033) in BAV patients with ascending aorta dilatation (group 1).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: Inflammation plays an important role in the pathophysiology of vascular disease.
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Key Findings & Data:The subjects were separated into two groups based on their ascending aorta diameter.
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Conclusion & Impact:Results: When the results were compared, it was demonstrated that there was a positive correlation between NLR and ascending aorta diameter (r: 0.485, P = 0.026), whereas there was a negative correlation between NLR and left ventricular end-diastolic diameter (r: 0.475, P = 0.030), left ventricular end-systolic diameter (r: 0.482, P = 0.027), and left ventricular ejection fraction (r: 0.467, P = 0.033) in BAV patients with ascending aorta dilatation (group 1).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: Inflammation plays an important role in the pathophysiology of vascular disease. In this study, we aimed to evaluate the associations of neutrophil to lymphocyte ratio (NLR; an indicator of inflammation) with left ventricular ejection fraction and ascending aorta diameter in patients with a bicuspid aortic valve (BAV). Materials and methods: One hundred and thirty-nine consecutive patients with the diagnosis of BAV were enrolled in the study. Complete blood counts were analyzed for neutrophil and lymphocyte levels and NLR. The subjects were separated into two groups based on their ascending aorta diameter. The patients with ascending aorta diameter equal to or above 3.9 cm were included in group 1 whereas those with ascending aorta diameter below 3.9 cm were included in group 2. Results: When the results were compared, it was demonstrated that there was a positive correlation between NLR and ascending aorta diameter (r: 0.485, P = 0.026), whereas there was a negative correlation between NLR and left ventricular end-diastolic diameter (r: 0.475, P = 0.030), left ventricular end-systolic diameter (r: 0.482, P = 0.027), and left ventricular ejection fraction (r: 0.467, P = 0.033) in BAV patients with ascending aorta dilatation (group 1).

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Cite This Article

DURMAZ, T., ASLAN, A. N., AKÇAY, M., AYHAN, H., KELEŞ, T., KASAPKARA, H. A., TURİNAY, Z. Ş., GÜNEY, M. C., BOZKURT, E. (2022). Higher neutrophil to lymphocyte ratio is related to a lower ejection fraction in bicuspid aortic valve patients. Turkish Journal of Medical Sciences, Cilt: 46 - Sayı: 4, 1144–1150. https://ajindex.com/articles/610698

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