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Journals / Turkish Journal of Immunology / 2018 / Cilt: 6 - Sayı: 1

The Relationship Between Serum Vitamin D (25(OH)D3), C-Peptide, and Interleukin-2 Level in Children with Type 1 Diabetes Mellitus

Tip 1 Diabetes Mellitus’lu Çocuklarda Serum D Vitamini (25(OH)D3), C-Peptid ve İnterlökin-2 Seviyeleri Arasındaki İlişki

Edi WİDJAJANTO
Andreas Budi WİJAYA
Harjoedi Adji TJAHJONO
Vivi RATNASARİ
Pages
16–22
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Serum level of vitamin D (25(OH)D3), C-Peptide, and Interleukin-2 between two groups were measured byusing Indirect ELISA.Results: Serum vitamin D (25(OH)D3), C-Peptide, and Interleukin-2 level between both groups were significantlydifferent (p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Vitamin D is very important for Type 1 diabetes mellitus (T1 DM) pathogenesis, and plays major role inthe regulation of pancreatic beta cells.
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Key Findings & Data:However, serum vitamin D (25(OH)D3) level related to inflammatory conditionin T1 DM has not been sufficiently investigated.
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Conclusion & Impact:Serum level of vitamin D (25(OH)D3), C-Peptide, and Interleukin-2 between two groups were measured byusing Indirect ELISA.Results: Serum vitamin D (25(OH)D3), C-Peptide, and Interleukin-2 level between both groups were significantlydifferent (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Vitamin D is very important for Type 1 diabetes mellitus (T1 DM) pathogenesis, and plays major role inthe regulation of pancreatic beta cells. However, serum vitamin D (25(OH)D3) level related to inflammatory conditionin T1 DM has not been sufficiently investigated. Therefore, we aimed to investigate the relationship between serumvitamin D (25(OH)D3), C-Peptide, and Interleukin-2 levels in children with T1 DM.Material and Methods: Blood samples from 20 subjects of T1 DM patients and healthy patients were collected, andanalyzed. Serum level of vitamin D (25(OH)D3), C-Peptide, and Interleukin-2 between two groups were measured byusing Indirect ELISA.Results: Serum vitamin D (25(OH)D3), C-Peptide, and Interleukin-2 level between both groups were significantlydifferent (p

Özet

Giriş: D vitamini, tip 1 diabetes mellitus (T1 DM) oluşumunda pankeasta beta hücre düzenlenmesinde çok önemlidir ve pankreastaki beta hücrelerini düzenler. Ancak, serumdaki D vitamini (25(OH)D3) seviyesinin T1 DM hastalarında, inflamatuvar durum ile ilişkisi yeterli düzeyde araştırılmamıştır. Bu nedenle, çalışmamızda T1 DM tanısı alan çocuklarda serum D vitamini, C-peptid ve İnterlökin-2 düzeyleri arasındaki ilişkinin saptanmasıı amaçlanmıştır. Gereçler ve Yöntemler: T1 DM olan 20 hastanın ve sağlıklı bireylerin kan örneklerini alarak irdeledik. Serum örneklerinde D vitamini (25(OH)D3), C-Peptid ve İnterlökin-2 düzeyleri inderekt ELISA tetsi ile ölçüldü. Bulgular: Her iki gruptaki serum D vitamini (25(OH)D3), C-peptid ve İnterlökin-2 düzeyleri anlamlı düzeyde birbirinden farklılık gösterdi (p

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Cite This Article

WİDJAJANTO, E., WİJAYA, A. B., TJAHJONO, H. A., RATNASARİ, V. (2022). The Relationship Between Serum Vitamin D (25(OH)D3), C-Peptide, and Interleukin-2 Level in Children with Type 1 Diabetes Mellitus. Turkish Journal of Immunology, Cilt: 6 - Sayı: 1, 16–22. https://ajindex.com/articles/607218

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