Only iridoid 2 exhibited weak cytotoxicity against all tested cell lines with IC50 values ranging from 60.19 to 69.14 μM.
📌 3 Key Takeaways
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Objective & Hypothesis:A phytochemical investigation of the stems of Myoporum bontioides (Sieb. et Zucc.) A.
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Key Findings & Data:Gray, a semimangrove plant distributed along coastlines of north-eastern Vietnam and some Asian countries led to the isolation of a new iridoid glucoside (1), named myobontioside E, together with fourteen known compounds (2- 15).
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Conclusion & Impact:Only iridoid 2 exhibited weak cytotoxicity against all tested cell lines with IC50 values ranging from 60.19 to 69.14 μM.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
A phytochemical investigation of the stems of Myoporum bontioides (Sieb. et Zucc.) A. Gray, a semimangrove plant distributed along coastlines of north-eastern Vietnam and some Asian countries led to the isolation of a new iridoid glucoside (1), named myobontioside E, together with fourteen known compounds (2- 15). Their structures were elucidated by means of HR ESI-MS, 1D and 2D NMR spectroscopy as well as comparison with the data reported in the literature. The cytotoxic effects on 8505C, MKN7, HT29, and T24 cell lines were assessed using SRB assay. Only iridoid 2 exhibited weak cytotoxicity against all tested cell lines with IC50 values ranging from 60.19 to 69.14 μM.
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Cite This Article
HOANG, V. D., MINH, T. T., THANH, N. T. V. (2022). A New Iridoid Glucoside from the Stems of Myoporum bontioides (Sieb.et Zucc.) A. Gray. Records of Natural Products, Cilt: 16 - Sayı: 5, 426–432. https://ajindex.com/articles/588742
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