Kistik Fibrozis Dışı Bronşektazide Bronş Aşırı Duyarlılığı

Objective & Hypothesis:Aim: Bronchiectasis is an abnormal dilatation of bronchi and bronchiolesdue to repeated cycles of airway infection and inflammation.

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Key Findings & Data:In the present study we investigated the existence of BHRand possible factors that could affect the BHR in bronchiectasis patients.Matherial and Method: Study performed in bronchiectasis outpatient clinic.We included 69 patients in which the diagnosis of bronchiectasis was madeby high-resolution computed tomography (HRCT).

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Conclusion & Impact:Female gender and low FEV1value were found to be important two factors to influence the developmentof bronchial hyperreactivity (p

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Aim: Bronchiectasis is an abnormal dilatation of bronchi and bronchiolesdue to repeated cycles of airway infection and inflammation. There is alimited data that support the existence of bronchial hyperreactivity (BHR)in bronchiectasis. In the present study we investigated the existence of BHRand possible factors that could affect the BHR in bronchiectasis patients.Matherial and Method: Study performed in bronchiectasis outpatient clinic.We included 69 patients in which the diagnosis of bronchiectasis was madeby high-resolution computed tomography (HRCT). Patients with cysticfibrosis, immune deficiency and asthma were excluded. We evaluated therelationship between the results of bronchial provocation test (BPT) andgender, duration of disease, smoking history, lung function tests, degreeof radiologic distribution, type of bronciectasis, existence of bacterialcolonisation and atopy. Results: We found that, bronchial hyperreactivity wasdetected in a much smaller proportion (29%) of patients with the diagnosisof bronchiectasis than the existing literature. Female gender and low FEV1value were found to be important two factors to influence the developmentof bronchial hyperreactivity (p

Özet

Amaç: Bronşektazi tekrarlayan hava yolu enfeksiyon ve inflamasyonları nedeniyle, bronş ve bronşiollerin anormal dilatasyonudur. Bronşektazide bronşaşırı duyarlılığı (BHR) varlığını destekleyen sınırlı sayıda çalışma mevcuttur.Bu çalışmada biz bronşektazi hastalarında BHR varlığını ve bunu etkileyebilecek olası faktörleri araştırdık. Gereç ve Yöntem: Çalışma bronşektazi hastaları takip polikliniğinde gerçekleştirildi. Yüksek çözünürlüklü bilgisayarlı tomografi (HRCT) ile bronşektazi tanısı konulmuş 69 hasta çalışmaya alındı.Kistik fibrozis, immune yetmezlik ve astım tanılı hastalar çalışma dışı bırakıldı. Bronş provakosyon testi, cinsiyet, hastalık süresi, sigara öyküsü, solunum fonksiyon testleri, radyolojik dağılım derecesi, bronşektazi tipi, bakterial kolonizasyon varlığı ve atopi arasındaki ilişki araştırıldı. Bulgular: Bronşektazi tanılı hastalarda bronş aşırı duyarlılığı literatürde olduğundan çok dahadüşük oranda ( %29) saptandı. Kadın cinsiyet ve düşük FEV1 düzeyi bronş aşırı duyarlılığı gelişimini etkileyen iki önemli faktör olarak bulundu (p

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Cite This Article

ŞERMİN, B., BENAN, M., IŞIL, U., BÜLENT, T., GÖKHAN, A., HATİCE, Y., NİGAR, H., MÜZEYYEN, E. (2022). Kistik Fibrozis Dışı Bronşektazide Bronş Aşırı Duyarlılığı. Journal of Clinical and Analytical Medicine, Cilt: 4 - Sayı: 3, 224–227. https://ajindex.com/articles/561257

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