Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2014 / Cilt: 54 - Sayı: 2

GASTRIC SIGNET-RING CELL LYMPHOMA; A CASE REPORT

GASTRİK TAŞLI YÜZÜK HÜCRELİ LENFOMA; OLGU SUNUMU

Pages
136–138
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Both cases, considered H &histochemical and immunohistochemical staining and in the light of clinical informationhigh grade diffuse large B-cell lymphomawas diagnosed. of in in of by E,

📌 3 Key Takeaways

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Objective & Hypothesis:Signet ring cell morphology is associated withclassicaladenocarcinoma.This morphologic pattern is a rare variantNon-Hodgkin lymphoma, more definedfollicular lymphoma.
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Key Findings & Data:The first case; 68 year old female patient pain in the left half of the periumblical region and constipation.
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Conclusion & Impact:Both cases, considered H &histochemical and immunohistochemical staining and in the light of clinical informationhigh grade diffuse large B-cell lymphomawas diagnosed. of in in of by E,
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Signet ring cell morphology is associated withclassicaladenocarcinoma.This morphologic pattern is a rare variantNon-Hodgkin lymphoma, more definedfollicular lymphoma. Frequently seenB cell follicular lymphomas, also in T cell lymphomas. Two gastric lymphoma cases with signet ring cell morphologic appearance were discussed according to the literatüre. The first case; 68 year old female patient pain in the left half of the periumblical region and constipation. Tumor markers (CA 125, CA 19 9, C 15 3, carcinoembryonic antigen (CEA)) were normal and she was made endoscopy prediagnosis by gastritis. The second patient, 64 years old male patient was admitted to our hospital with complaintsdyspepsia. At the lower end of the esophagus and cardia mass lesion is describedendoscopy. Both cases, considered H &histochemical and immunohistochemical staining and in the light of clinical informationhigh grade diffuse large B-cell lymphomawas diagnosed. of in in of by E,

Özet

Taşlı yüzük hücreli morfoloji klasik olarak adenokarsinom ile ilişkilidir. Non-Hodgkin lenfomanın ise nadir görülen bir varyantı olup, daha çok foliküler lenfomanın morfolojik bir paterni olarak tanımlanmıştır. Sıklıkla b hücreli foliküler lenfomanın bir varyantı olarak görülebilirken, t hücreli lenfomalarda da bu morfoloji olabilir1,3,6 . Taşlı yüzük hücreli morfolojik görünüme sahip iki gastrik lenfoma olgusu literatür bilgileri ışığında tartışılmıştır. İlk olgu; periumblikal bölge sol yarısında ağrı ve kabızlık şikayetleri olan 68 yaşında bayan hastadır. Tümör işaretleyicileri (CA 125, CA 19 9, CA 15 3,karsinoembriyonik antijen (CEA)) normal olan hastaya gastrit ön tanısıyla endoskopi yapılmıştır. İkinci olgu; 64 yaşında erkek hasta olup, hastanemize dispepsi yakınması ile başvurmuştur. Yapılan endoskopide özofagus alt uçta ve kardia da malign görünümlü kitlesel lezyon tariflenmiştir. Her iki vaka H&E , histokimyasal ve immünohistokimyasal boyamalar ve klinik bilgiler ışığında değerlendirildiğinde high grade diffüz büyük b hücreli lenfoma tanısı almıştır.

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Cite This Article

TOPAL, C. S., YILMAZ, M. S., KARABULUT, M. H., KIR, G., İHVAN, A. N. (2022). GASTRIC SIGNET-RING CELL LYMPHOMA; A CASE REPORT. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 54 - Sayı: 2, 136–138. https://ajindex.com/articles/535339

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References (1)

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