SavedAdd your journal

Journals / Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research) / 2008 / Cilt: 32 - Sayı: 1

The effect of head and neck radiotherapy on trace elements of saliva

Baş ve boyun radyoterapisinin tükürük eser elementlerine etkisi

Sema DURAL
Duygu BÜYÜKKÖPRÜ
Pages
82–90
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Observed fluctuations during radiotherapy have no statistical significance.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: In this study evalution of total trace metals, in the stimulated saliva of 22 nasopharynx and 23 larynx carcinoma patients subjected to radiography, is aimed.
📊
Key Findings & Data:Concentrations of trace elements (Al, Fe, Pb, Se, Zn, Cu and Ni) are determined using an Atomic Absorption Spectroscopy instrument (Perkin Elmer 5100 PC) equipped with Zeeman correction, HGA graphite furnace, AS-60 auto sampler and Oksidata Microline 320 printer.
💡
Conclusion & Impact:Observed fluctuations during radiotherapy have no statistical significance.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: In this study evalution of total trace metals, in the stimulated saliva of 22 nasopharynx and 23 larynx carcinoma patients subjected to radiography, is aimed. Materials and Methods: Paraffin stimulated saliva collected at three phases of radiotherapy (before radiotherapy, in the middle of the therapy and at the end) for determination. Concentrations of trace elements (Al, Fe, Pb, Se, Zn, Cu and Ni) are determined using an Atomic Absorption Spectroscopy instrument (Perkin Elmer 5100 PC) equipped with Zeeman correction, HGA graphite furnace, AS-60 auto sampler and Oksidata Microline 320 printer. The results of the study statistically evaluated. Results: Evaluation of the trace elements concentrations results in saliva revealed no statistically significant difference among nasopharynx carcinoma patients. Only zinc concentration has increased among larynx carcinoma patients during radiotherapy. Conclusion: Radiotherapy treatment applied to head and neck had no significant effect on the concentrati-on of trace elements in saliva. Observed fluctuations during radiotherapy have no statistical significance.

Özet

Amaç: Bu çalışmada, baş ve boyun bölgesinden radyoterapi alan 22 nazofarenks ve 23 larenks karsinomalı hastanın parafin ile stimüle edilmiş toplam tükürüklerindeki eser elementlerin değerlendirilmesi amaçlanmıştır. Gereç ve yöntem: Tükürük ölçümleri için parafin ile stimüle edilen toplam tükürük kullanılarak, radyoterapinin üç aşamasında (radyoterapiden önce, radyoterapinin ortasında ve sonunda) ölçümler yapılmıştır. Eser elementlerin; (Al, Fe,Pb,Se, Zn, Cu ve Ni) derişimleri, Perkin-Elmer 5100 PC Atomik Absorpsiyon Spektrofotometresi, HGA Grafit Fırın, AS-60 Aotosampler, Zeeman Zemin Düzenleyici ile Oksidata Microline 320 yazıcıdan oluşan bir sistem kullanılarak belirlenmiştir. Elde edilen ölçüm sonuçları istatistiksel olarak değerlendirilmiştir. Bulgular: Bu ölçümlerin değerlendirilmesinde, nazofarinks karsinomalı hastaların, radyoterapi boyunca tükrük eser element konsantrasyonlarında istatistiksel olarak anlamlı bir değişiklik görülmemiştir. Larinks karsinomalı hastaların ise radyoterapi süresince tükürüklerinde sadece çinko konsantrasyonunun arttığı gözlenmiştir.Sonuç: Baş ve boyuna uygulanan radyoterapinin tükürük eser elemetlerinin miktarını çok fazla etkilemediği, radyoterapi boyunca değerlerde bir dalgalanma olduğu ancak , bunun istatistiksel olarak önemli olmadığı görülmüştür.

🔖

Cite This Article

DURAL, S., BÜYÜKKÖPRÜ, D. (2022). The effect of head and neck radiotherapy on trace elements of saliva. Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research), Cilt: 32 - Sayı: 1, 82–90. https://ajindex.com/articles/528395

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Mossman KL. Frequent Short Term Oral Complications of Head and Neck Radiotherapy. ENT Journal(1994) 316–320
  2. Glass JB, Langlais RP, Xerostomia: Diagnosis and Treatment Planning Consideration. Oral Surg. Oral Med. Oral Pathol. (1984) 58: 248–252 3. Andrews N, Griffiths C. Dental Complications of Head and Neck Radiotherapy. Part 2 Aut.Dent. J. (2001) 46: 174–182
  3. Zahir S,Sarkar S. Study of trace elements in mixed saliva of caries free and caries active children.J. İnd.Soc. Pedodon.and Preven.Dentis.(2006). 24: 27–29
  4. Reitznerova, E, Amarasiriwardena, D, Kopcakova M. Determination of trace elements in human tooth enamel. Fresenius J Anal Chem. (2000) 367: 748- 754
  5. İshi K, Sato M, Akita M. Localization of Zinc in the Rat Submandibular Gland and the Effect of Ist Deficiency on Salivary Secretion,Ann.Otol.Rhinol.Laryngol: (1999) 108:300-308
  6. Navazeh M. Methods For Collecting Saliva.,Saliva as a diagnostic fluid.,Editors Malamud D, Tabak L. Annals of the New York Academy of Sciences,.(1993) 694: 72-77
  7. Duggal MS,Chawia HS, Curzon M.E.J. A study of the relationship between trace elements in saliva and dental caries in children. Arch Oral Biol.:(1991) 36: 881–884
  8. Mathur A, Wallenius K, Abdulla M. Relation between zinc content in saliva and blood in healty human adults. Scand. J. Clin.Lab.İnvest. (1977).59: 469–472
  9. Henkin RL, Mueller CW, Wolf RO. Estimation of zinc concentration of parotid saliva by flamless atomic absorbtion spectrophotometry in normal subjects and in patients with idiophathic hypogeusia. J.Lab.Clin.Med.(1970) 86: 175–180
  10. Hadjimarkos DM, Shearer TR. Selenium concentration in human saliva. Am.J.Clin.Nutr.(1971) 24:1210-1211
  11. Eisenberg AD,Curson MEJ, Fernandez EJ. Interactions of selenium fluoride on growth, glicolysis and survival of streptecoccus mutans GS-5.Caries Res.(1990). 24: 306–311
  12. Dreizen S, Levy BM. Comparative concentraions of selected trace metals in human and marmoset saliva. Archs. Oral. Biol.(1970) 15: 179–188.